Search results for "pharmaceutical"

showing 10 items of 3243 documents

Supplemental Material, Table_S2 - Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish

2020

Supplemental Material, Table_S2 for Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish by Chuanrui Zheng, Letian Shan, Peijian Tong and Thomas Efferth in Dose-Response

110320 Radiology and Organ ImagingFOS: Clinical medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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Supplemental Material, Table_S1 - Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish

2020

Supplemental Material, Table_S1 for Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish by Chuanrui Zheng, Letian Shan, Peijian Tong and Thomas Efferth in Dose-Response

110320 Radiology and Organ ImagingFOS: Clinical medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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sj-pdf-2-imr-10.1177_0300060520982657 - Supplemental material for Evaluation of main functional dyspepsia symptoms after probiotic administration in …

2021

Supplemental material, sj-pdf-2-imr-10.1177_0300060520982657 for Evaluation of main functional dyspepsia symptoms after probiotic administration in patients receiving conventional pharmacological therapies by Lorenzo Drago, Gabriele Meroni, Dario Pistone, Luigi Pasquale, Giuseppe Milazzo, Fabio Monica, Salvatore Aragona, Leonardo Ficano, Roberto Vassallo and Gastrobiota Group in Journal of International Medical Research

111199 Nutrition and Dietetics not elsewhere classifiedCardiology170199 Psychology not elsewhere classified111799 Public Health and Health Services not elsewhere classified110604 Sports MedicineFOS: Health sciences110306 Endocrinology110308 Geriatrics and Gerontology111099 Nursing not elsewhere classified111708 Health and Community Services160807 Sociological Methodology and Research Methods111702 Aged Health Care111403 Paediatrics110904 Neurology and Neuromuscular Diseases110203 Respiratory Diseases110315 OtorhinolaryngologyFOS: Clinical medicine110319 Psychiatry (incl. Psychotherapy)FOS: SociologyFOS: Psychology110599 Dentistry not elsewhere classified110323 Surgery110305 Emergency Medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified111299 Oncology and Carcinogenesis not elsewhere classified110314 Orthopaedics
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sj-pdf-1-imr-10.1177_0300060520982657 - Supplemental material for Evaluation of main functional dyspepsia symptoms after probiotic administration in …

2021

Supplemental material, sj-pdf-1-imr-10.1177_0300060520982657 for Evaluation of main functional dyspepsia symptoms after probiotic administration in patients receiving conventional pharmacological therapies by Lorenzo Drago, Gabriele Meroni, Dario Pistone, Luigi Pasquale, Giuseppe Milazzo, Fabio Monica, Salvatore Aragona, Leonardo Ficano, Roberto Vassallo and Gastrobiota Group in Journal of International Medical Research

111199 Nutrition and Dietetics not elsewhere classifiedCardiology170199 Psychology not elsewhere classified111799 Public Health and Health Services not elsewhere classified110604 Sports MedicineFOS: Health sciences110306 Endocrinology110308 Geriatrics and Gerontology111099 Nursing not elsewhere classified111708 Health and Community Services160807 Sociological Methodology and Research Methods111702 Aged Health Care111403 Paediatrics110904 Neurology and Neuromuscular Diseases110203 Respiratory Diseases110315 OtorhinolaryngologyFOS: Clinical medicine110319 Psychiatry (incl. Psychotherapy)FOS: SociologyFOS: Psychology110599 Dentistry not elsewhere classified110323 Surgery110305 Emergency Medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified111299 Oncology and Carcinogenesis not elsewhere classified110314 Orthopaedics
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sj-pdf-1-imr-10.1177_03000605211073305 - Supplemental material for Guanidinoacetate���creatine in secondary progressive multiple sclerosis: a case re…

2022

Supplemental material, sj-pdf-1-imr-10.1177_03000605211073305 for Guanidinoacetate���creatine in secondary progressive multiple sclerosis: a case report by Sergej M. Ostojic, Jelena Ostojic, Dragana Zanini, Tatjana Jezdimirovic and Valdemar Stajer in Journal of International Medical Research

111199 Nutrition and Dietetics not elsewhere classifiedCardiology170199 Psychology not elsewhere classified111799 Public Health and Health Services not elsewhere classified110604 Sports MedicineFOS: Health sciences110306 Endocrinology110308 Geriatrics and Gerontology111099 Nursing not elsewhere classified111708 Health and Community Services160807 Sociological Methodology and Research Methods111702 Aged Health Care111403 Paediatrics110904 Neurology and Neuromuscular Diseases110203 Respiratory Diseases110315 OtorhinolaryngologyFOS: Clinical medicine110319 Psychiatry (incl. Psychotherapy)FOS: SociologyFOS: Psychology110599 Dentistry not elsewhere classified110323 Surgery110305 Emergency Medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified111299 Oncology and Carcinogenesis not elsewhere classified110314 Orthopaedics
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Synthesis, Stability and Relaxivity of TEEPO-Met: An Organic Radical as a Potential Tumour Targeting Contrast Agent for Magnetic Resonance Imaging

2018

Cancer is a widespread and life-threatening disease and its early-stage diagnosis is vital. One of the most effective, non-invasive tools in medical diagnostics is magnetic resonance imaging (MRI) with the aid of contrast agents. Contrast agents that are currently in clinical use contain metals, causing some restrictions in their use. Also, these contrast agents are mainly non-specific without any tissue targeting capabilities. Subsequently, the interest has notably increased in the research of organic, metal-free contrast agents. This study presents a new, stable organic radical, TEEPO-Met, where a radical moiety 2,2,6,6-tetraethylpiperidinoxide (TEEPO) is attached to an amino acid, methio…

116 Chemical sciencesPharmaceutical ScienceContrast Media01 natural sciencesAnalytical Chemistrylaw.inventionGLUCOSENuclear magnetic resonancePiperidineslawHeterocyclic CompoundsNeoplasmsDrug DiscoveryMoietymagneettitutkimusSpin labelElectron paramagnetic resonanceta116orgaaniset yhdisteetmedicine.diagnostic_testMolecular StructureChemistryPhantoms ImagingRelaxation (NMR)radicalsMagnetic Resonance Imaging3. Good healthChemistry (miscellaneous)Molecular MedicineMRIRadical010402 general chemistryvapaat radikaalitImaging phantomArticleCyclic N-OxidesvarjoainetutkimusnitroxidesmedicineAnimalsHumanscontrast agentstyppiyhdisteetPhysical and Theoretical Chemistrymethionine010405 organic chemistryOrganic ChemistryElectron Spin Resonance SpectroscopyMagnetic resonance imagingIN-VITRO3126 Surgery anesthesiology intensive care radiologynitroxides; radicals; methionine; contrast agents; MRI; NMR; EPRIn vitroNMRTRANSPORT0104 chemical sciencesREDUCTIONSPIN-LABEL1182 Biochemistry cell and molecular biologyEPRMolecules; Volume 23; Issue 5; Pages: 1034
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Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-(thi)one derivatives.

2002

Several 2,3-diaryl-1,3-thiazolidine-4-thione derivatives and 2,3-diaryl-1,3-thiazolidin-4-ones bearing a methyl group at C-5 position have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.

23-Diaryl-13-thiazolidine-4-thioneAnti-HIV activity23-Diaryl-13-thiazolidin-4-oneStereochemistryAnti-HIV AgentsCell SurvivalPharmaceutical ScienceVirus ReplicationChemical synthesischemistry.chemical_compoundInhibitory Concentration 50Structure-Activity RelationshipThiadiazolesDrug DiscoveryThiadiazolesmedicineTumor Cells CulturedStructure–activity relationshipHumansAnti hiv activityReverse-transcriptase inhibitorGeneral MedicineSettore CHIM/08 - Chimica FarmaceuticaIn vitrochemistryNNRTIsLactamHIV-1EpimerMethyl groupmedicine.drugFarmaco (Societa chimica italiana : 1989)
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NO donors. Part 16: investigations on structure-activity relationships of organic mononitrates reveal 2-nitrooxyethylammoniumnitrate as a high potent…

2007

The vasoactive properties of 14 organic mononitrates were investigated in vitro using PGF(2alpha)-precontracted porcine pulmonary arteries. A surprisingly wide range of vasorelaxant potencies was observed (pD(2): 3.36-7.50). Activities showed to be highly sensitive to the molecular structure and the substituents at the molecular carrier of the nitrate group. A correlation between lipophilicity and vasorelaxant potency could not be recognized. 2-Nitrooxyethylammoniumnitrate (1) was found to be slightly superior to the high potency trinitrate GTN.

2-nitrooxyethylammoniumnitrateNitratesChemistryStereochemistryVasodilator AgentsOrganic ChemistryClinical BiochemistryPharmaceutical ScienceVasodilationBiochemistryChemical synthesisIn vitroNo donorsQuaternary Ammonium CompoundsStructure-Activity RelationshipDrug DiscoveryLipophilicityMolecular MedicinePotencyStructure–activity relationshipNitric Oxide DonorsMolecular BiologyBioorganicmedicinal chemistry letters
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Nanotechnology against COVID-19: Immunization, diagnostic and therapeutic studies.

2021

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020 soon led to the global pandemic of Coronavirus Disease 2019 (COVID-19). Since then, the clinical and scientific communities have been closely collaborating to develop effective strategies for controlling the ongoing pandemic. The game-changing fields of recent years, nanotechnology and nanomedicine have the potential to not only design new approaches, but also to improve existing methods for the fight against COVID-19. Nanomaterials can be used in the development of highly efficient, reusable personal protective equipment, and antiviral nano-coatings in public settings could prevent the spread of SAR…

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pharmaceutical ScienceNanotechnology02 engineering and technologyReview Article03 medical and health sciencesPandemicDiagnosisMedicineHumansNanotechnologyPandemics030304 developmental biology0303 health sciencesbusiness.industrySARS-CoV-2COVID-19021001 nanoscience & nanotechnologyClinical trialNanovaccineImmunizationNanomedicineImmunizationNanocarriers0210 nano-technologybusinessJournal of controlled release : official journal of the Controlled Release Society
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Zinc(II)—The Overlooked Éminence Grise of Chloroquine’s Fight against COVID-19?

2020

The authors would like to thank Agnieszka Michalczuk for providing us with her artistic vision of SARS-CoV-2.

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)lcsh:Medicinelcsh:RS1-441Pharmaceutical Sciencechemistry.chemical_elementZincReviewlcsh:Pharmacy and materia medicachloroquine03 medical and health scienceschemistry.chemical_compoundChloroquineRNA polymeraseDrug Discoverymedicine030304 developmental biology0303 health sciences030306 microbiologybusiness.industrySARS-CoV-2lcsh:RCOVID-19HydroxychloroquineChloroquinehydroxy- chloroquineVirologychemistry2019-nCoVMolecular MedicinebusinessZn(II) ionophoresmedicine.drugHydroxychloroquinePharmaceuticals
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