Search results for "pharmaceutical"
showing 10 items of 3243 documents
Increasing Yield and Antioxidative Performance of Litchi Pericarp Procyanidins in Baked Food by Ultrasound-Assisted Extraction Coupled with Enzymatic…
2018
Extraction with organic solvents is a traditional method to isolate bioactive compounds, which is energy-wasting and time-consuming. Therefore, enzyme and ultrasound treatments were combined to assist the extraction of oligomeric procyanidins from litchi pericarp (LPOPC), as an innovative approach to replace conventional extraction methods. Under optimum conditions (enzyme concentration 0.12 mg/mL, ultrasonic power 300 W, ultrasonic time 80 min, and liquid/solid ratio 10 mL/g), the yield of LPOPC could be improved up to 13.5%. HPLC analysis indicated that the oligomeric procyanidins (OPC) content of LPOPC from proposed extraction was up to 89.6%, mainly including (&minus
Hormesis: Decoding Two Sides of the Same Coin
2015
In the paradigm of drug administration, determining the correct dosage of a therapeutic is often a challenge. Several drugs have been noted to demonstrate contradictory effects per se at high and low doses. This duality in function of a drug at different concentrations is known as hormesis. Therefore, it becomes necessary to study these biphasic functions in order to understand the mechanistic basis of their effects. In this article, we focus on different molecules and pathways associated with diseases that possess a duality in their function and thus prove to be the seat of hormesis. In particular, we have highlighted the pathways and factors involved in the progression of cancer and how t…
Impact of Ageing on Pea Protein Volatile Compounds and Correlation with Odor
2022
Vegetal proteins are of high interest for their many positive aspects, but their ‘beany’ off-flavor is still limiting the consumer’s acceptance. The aim of this work was to investigate the conservation of pea protein isolate (PPI) during time and especially the evolution of their organoleptic quality under two storage conditions. The evolution of the volatile compounds, the odor and the color of a PPI has been investigated during one year of storage. PPI was exposed to two treatments mimicking a lack of control of storage conditions: treatment A with light exposition at ambient temperature (A—Light 20 °C) and treatment B in the dark but with a higher temperature …
Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine C…
2021
Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present work, the two mentioned approaches were coupled by conjugating ocular permeation enhancers (PEG2000, carnitine, creatine, taurine) to an inulin-based co-polymer (INU-EDA-RA) in order to obtain self-assembling biopolymers with permeation enhancer properties for the hydrophobic drug dexamethasone (DEX). Inulin derivatives were properly synthetized, were found to expose about 2% mol/mol of enhancer molecules in the side chain, and resulted abl…
Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019)
2021
© 2021 by the authors.
Reklāmas ietekme uz klienta izvēli iepirkties interneta aptiekā
2017
Interneta aptiekas ir ieguvušas plašu izplatību pasaulē, jo mūsdienās patērētājs vēlas iepirkties ērti un izdevīgi. Tādējādi rodas nepieciešamība meklēt jaunus instrumentus komunikācijas veidošanai, tai skaitā, reklāmas kā komunikācijas veida radīšanas gaitā. Farmācijas tirgus apstākļos reklāma ir obligāts nosacījums preču realizēšanai un svarīgs instruments konkurences cīņā. Sakarā ar nepārtrauktām izmaiņām farmācijas industrijas jomā, ir nepieciešamas jaunas ārstniecības līdzekļu virzīšanas metodes. Praktiskā darba rezultātā tika noteikti respondentu galvenie interneta aptiekas iepirkšanas iemesli, reklāmas informācijas ieguves avoti, visbiežāk pirktās preces interneta aptiekā reklāmas ie…
The Particularities of Pharmaceutical Care in Improving Public Health Service during the COVID-19 Pandemic
2021
Nowadays, humanity is confronted with one of the most difficult challenges. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was identified for the first time in Hubei, China in December 2019 and produced the COVID-19 pandemic, a devastating disease that led to many complications and deaths. The authorities and the global healthcare system have been alerted regarding the prevention and treatment of this pathology. Even though worldwide quarantine was declared, health care professionals, including pharmacists, have been at the frontline in this war. Since the beginning of the pandemic, the authorities relied on the involvement of the community, hospital, or clinical pharmacists i…
Scientific Methodology. Pharmacy degree
2021
El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València La asignatura "Documentación y Metodología Científica", impartida en el primer cuatrimestre de primero del grado de farmacia, combina diversas áreas de conocimiento entre las que se incluyen historia de la ciencia, antropología, sociología o epistemología. Pensada desde la óptica del plan Bolonia, la asignatura ha sido reformada gracias a un proyecto de innovación docente, basado en la construcción del conocimiento por parte del alumnado y un trabajo de reflexión y participación en clase continuo. Esta presentación incluye las guías de cada uno de los t…
Pharmacy Practice and Education in Latvia
2018
Pharmacies in Bulgaria have a monopoly on the dispensing of medicinal products that are authorized in the Republic of Bulgaria, as well as medical devices, food additives, cosmetics, and sanitary/hygienic articles. Aptekari (pharmacists) act as responsible pharmacists, pharmacy owners, and managers. They follow a five year Masters of Science in Pharmacy (M.Sc. Pharm.) degree course with a six month traineeship. Pomoshnik-farmacevti (assistant pharmacists) follow a three year degree with a six month traineeship. They can prepare medicines and dispense OTC medicines under the supervision of a pharmacist. The first and second year of the M.Sc. Pharm. degree are devoted to chemical sciences, ma…
Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspec…
2019
Abstract Corylus avellana (hazelnut) is one of the most popular tree nuts on a worldwide basis. The main products of C. avellana are kernels, a nutritious food, with a high content of healthy lipids, contained in a hard shell. In recent years, along with the ongoing research carried out on hazelnut kernels, a growing interest has been addressed to the hazelnut byproducts including hazelnut skin, hazelnut hard shell, and hazelnut green leafy cover as well as hazelnut tree leaf. These byproducts deriving from the roasting, cracking, shelling/hulling, and harvesting processes have been found as a source of “phytochemicals” with biological activity. The aim of this review is to provide a compre…