Search results for "pharmacy"

Oral drug therapy following bariatric surgery: an overview of fundamentals, literature and clinical recommendations

2016

Bariatric surgery is the most effective solution for severe obesity and obesity with comorbidities, and the number of patients going through bariatric surgery is rapidly and constantly growing. The modified gastrointestinal anatomy of the patient may lead to significant pharmacokinetic alterations in the oral absorption of drugs after the surgery; however, because of insufficient available literature and inadequate awareness of the medical team, bariatric surgery patients may be discharged from the hospital with insufficient instructions regarding their medication therapy. In this article, we aim to present the various mechanisms by which bariatric surgery may influence oral drug absorption…

Risk Factors for Secondary Cancer in a Case-Control Study on 1,259 Patients with Myeloproliferative Neoplasms

2018

Abstract INTRODUCTION The incidence of secondary cancer (SC) in patients with myeloproliferative neoplasms (MPN) is high and comparable to that of thrombosis. However, the identification of patient subgroups that might be at increased susceptibility of developing SC has not been systematically addressed. We report here the results of an international case-control study (MPN-K) aimed at comparing the frequency of exposure to possible causes of SC in patients with classical MPN, polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF). METHODS This European Leukaemia Network (ELN) study reports MPN patients from 28 sites of 5 European countries and Israel, diagnosed in th…

Haemoperfusion: a useful therapy for a severely poisoned patient?

1986

Although it is many years since a haemodialysis and haemoperfusion over uncoated and later coated charcoal columns have been used for the treatment of intoxicated patients, the clinical efficacy of these extracorporeal techniques in the treatment of severely poisoned patients remains a matter of debate. Some of the reasons for this controversy may be the indiscriminate use of haemoperfusion in any form of intoxication, the lack of well-controlled studies and the wrong interpretation of the high haemoperfusion clearance values sometimes obtained. Simple pharmacokinetic principles are applied to this type of treatment and some practical guidelines as to how and when haemoperfusion should be …

Role of the hospital pharmacist in an Italian antimicrobial stewardship programme

2020

The inappropriate use of antimicrobial agents is contributing to an increasing phenomenon of bacterial resistance. For this reason, there is a growing interest in ‘antimicrobial stewardship’, a series of coordinated and multidisciplinary interventions aimed to promote the safe and appropriate use of antimicrobials in which the pharmacist’s contribution is necessary for the optimal choice of drug, dose, duration of therapy and the implementation of cost containment strategies. AIM OF THE STUDY: We wanted to create a reference model and a specific training manual on antibiotic stewardship to introduce the role of the department pharmacist with specific infection disease skills in the Italian …

STUDY OF LIFE QUALITY AND TREATMENT SATISFACTION OF ROMANIAN DIABETIC PATIENTS

2019

In Romania, antidiabetic medication is free, based on a program of the Ministry of Public Health: “Treatment of patients with diabetes mellitus”. Since October 1, 2006, antidiabetic drugs have been delivered through open circuit pharmacies in contractual relationship with the National Health Insurance House, after four years of centralized delivery through hospital pharmacies.
 Objectives: This study aims to describe the influences of the diabetes treatment regarding patients’ quality of life and their satisfaction.
 Methods: A cross-sectional descriptive study was performed in pharmacies. The study includes 477 patients with diabetes mellitus from Cluj County, Romania. The interv…

Stressing the Importance of Adult Immunization: Suggestions for How to Change the Paradigm

2019

From 24 to 26 May 2017, the European Interdisciplinary Council on Ageing (EICA) and the European Union Geriatric Medicine Society (EUGMS) brought together a group of key opinion leaders and stakeholders from the healthcare field, for a conference entitled “Changing the Paradigm: Stressing the Importance of Adult Immunization”. The specific objectives of this meeting were to review vaccine-preventable diseases (VPDs) and vaccine performance in older adults and analyse the impact of the adult vaccination campaigns currently being implemented in Europe. The meeting aimed to improve our understanding of the challenge that vaccine hesitancy or scepticism represents, and how existing barriers to …

Health Tecnology Assessment: bisogni formativi teorici e pratici nelle Scuole di Specializzazione in Igiene e Medicina Preventiva

2010

Objective: The aim of our study was to perform a survey of Italian graduate students (medical doctors) attending Public Health Schools, in order to assess the importance and training needs concerning Health Technology Assessment (HTA) during their public health postgraduate education. Methods: In July 2010, we sent by e-mail a questionnaire to all graduate medical students attending Public Health Schools from four Italian Regions (representing Northern, Center and Southern Italy). The questionnaire included two sections: 1) knowledge on HTA; 2) assessment of the importance of HTA training during academic public health education. Main results: Eighty-two Public Health graduate students from …

Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes

2014

Objective The purpose of this study was to evaluate the contamination rate of media-fill products either prepared automated with a robotic system (APOTECAchemo™) or prepared manually at cytotoxic workbenches in the same cleanroom environment and by experienced operators. Media fills were completed by microbiological environmental control in the critical zones and used to validate the cleaning and disinfection procedures of the robotic system. Methods The aseptic preparation of patient individual ready-to-use injection solutions was simulated by using double concentrated tryptic soy broth as growth medium, water for injection and plastic syringes as primary packaging materials. Media fills w…

The causes of low adherence in patients with antihypertensive therapy

2016

Low adherence to antihypertensive therapy is a major cause of adverse cardiovascular outcomes by uncontrolled high blood pressure. If the most frequent causes of inappropriate taking of medicine are identified, possible improvements within the health care could be performed, promoting the safety and efficacy of antihypertensive therapy. The aim was to find the factors affecting patient's adherence during antihypertensive therapy. In the period from June to September 2014 a quantitative study was carried out including patients with diagnosed arterial hypertension who visited pharmacies in Riga to get the antihypertensive therapy. The study collected data of 152 patients with the mean antihyp…

2019

This study investigated the use of performance-enhancing substances in recreational triathletes who were competing in German races at distances ranging from super-sprint to long-distance, as per the International Triathlon Union. The use of legal drugs and over-the-counter supplements over the previous year, painkillers over the previous 3 months, and the potential three-month prevalence of physical doping and or cognitive doping in this group were assessed via an anonymous questionnaire. The Randomised Response Technique (RRT) was implemented for sensitive questions regarding “prescription drugs […] for the purpose of performance enhancement […] only available at a pharmacy or on the black…