Search results for "phenolic"

showing 10 items of 200 documents

Metabolite profile and in vitro activities of Phagnalon saxatile (L.) Cass. relevant to treatment of Alzheimer’s disease

2009

The present study describes for the first time the in vitro properties (inhibition of NO production and anticholinesterase) of Phagnalon saxatile (L.) Cass. (Asteraceae). The methanolic extract showed antioxidant activity that was measured by DPPH assay and beta-carotene bleaching test. The same extract inhibited NO production in the murine monocytic macrophage cell line RAW 264.7. Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition was assessed by modifications of Ellman's method. Purification of the MeOH extract of P. saxatile allowed the isolation of phenolic compounds. Among them, the compounds that most effectively inhibited lipopolysaccharide-induced NO production …

AntioxidantDPPHmedicine.medical_treatmentMetaboliteAsteraceaePharmacologyNitric OxideInhibition of NO productionCell LineMicechemistry.chemical_compoundPhagnalon saxatileAlzheimer DiseaseDrug DiscoverymedicineCaffeic acidAnimalsHumansSettore BIO/15 - Biologia FarmaceuticaIC50ButyrylcholinesterasePharmacologyPlant Extractsinhibition of NO production Alzheimer's diseaseSettore CHIM/06 - Chimica OrganicaGeneral MedicineAcetylcholinesterasePhenolic compoundsAlzheimers diseasechemistryBiochemistryPhagnalon saxatile asteraceae phenolic compoundButyrylcholinesteraseAcetylcholinesteraseCholinesterase InhibitorsLuteolinJournal of Enzyme Inhibition and Medicinal Chemistry
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Valorization of Wastewater from Table Olives: NMR Identification of Antioxidant Phenolic Fraction and Microwave Single-Phase Reaction of Sugary Fract…

2021

The table olive industry is producing a huge amount of wastewater, which is a post-processing cost and an environmental concern. The present study aims to valorize this processing by-product to obtain a value-added product, thereby enhancing resource efficiency and contributing to achieving sustainable development goals (SDGs). In this sense, a chemical reaction-based platform was developed to obtain valuable components, such as levulinic acid (LA) and 5-hydromethylfurfural (HMF). The products were then analyzed using NMR identification of the antioxidant phenolic fraction and microwave single-phase reaction of the sugary fraction. According to the results, the highest concentration of phen…

AntioxidantPhysiologymedicine.medical_treatmentClinical Biochemistrytable olive wastewaterFraction (chemistry)RM1-950phenolic compoundslevulinic acidBiochemistryChemical reactionArticlechemistry.chemical_compoundmedicineLevulinic acidresource efficiencySingle phaseHMFMolecular BiologyNutricióChemistryCell BiologyPulp and paper industryNMRwaste valorizationWastewaterMicrowave irradiationTherapeutics. PharmacologyMicrowaveAntioxidants
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Polyphenols pattern and correlation with antioxidant activities of berries extracts from four different populations of SicilianSambucus nigraL.

2014

Sambucus nigra L. (Caprifoliaceae) is wide spread in temperate and sub-tropical zones. The consumption of its berries has been associated with health benefits especially for its high content of natural antioxidants such as polyphenols, in particular anthocyanins. In this work we investigated the polyphenolic composition and the in vitro antioxidant activities (ABTS, DPPH, BCB and FRAP-ferrozine (FRAP-FZ) assays) of S. nigra berries, collected in four different Sicilian areas (Italy). Elderberries are considered one of the fruits with highest anthocyanins content, the amount of phenolic compounds, other than anthocyanins, is approximately 1.5 times greater than the latter. The LC–MS analyses…

AntioxidantSettore AGR/05 - Assestamento Forestale E SelvicolturaDPPHmedicine.medical_treatmentantioxidant activityPlant ScienceSambucus nigraBiochemistryAntioxidantsAnalytical ChemistryAnthocyaninschemistry.chemical_compoundSambucus nigrapolyphenolic compositionBotanymedicineSambucus nigra berries polyphenolic composition antioxidant activitySettore BIO/15 - Biologia FarmaceuticaFood scienceCaprifoliaceaeChromatography High Pressure LiquidABTSMolecular StructurebiologyChemistryOrganic ChemistryPolyphenolsSettore CHIM/06 - Chimica Organicabiology.organism_classificationlanguage.human_languageItalySambucusPolyphenolFruitlanguageComposition (visual arts)Oxidation-ReductionSicilianberrieNatural Product Research
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Effect of ferulic acid and α-tocopherol antioxidants on properties of sodium caseinate edible films

2011

Edible films, based on sodium caseinate containing three different concentrations of ferulic acid or alpha-tocopherol (20, 40 and 60 mg/g sodium caseinate), were obtained in order to evaluate the effect of these compounds on properties of the caseinate matrices. Special emphasis was placed on their effect on the films' oxygen barrier properties, which are decisive in the prevention of the oxidation of foods containing lipids. Films were characterized as to their tensile, optical and surface properties as well as their barrier properties to water vapor, oxygen and aroma compounds (n-hexanal and n-hexanol). Ferulic acid was more efficient at reducing oxygen and n-hexanal permeability than alp…

AntioxidantTECNOLOGIA DE ALIMENTOSGeneral Chemical Engineeringmedicine.medical_treatmentInorganic chemistrychemistry.chemical_elementOxygenFerulic acidchemistry.chemical_compoundUltimate tensile strengthmedicineTocopherolAromabiologyFerulic acidAlpha-TocopherolGeneral ChemistryPhenolic acidbiology.organism_classificationEdible filmsSodium caseinatechemistryalpha-TocopherolFood ScienceNuclear chemistryFood Hydrocolloids
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Effect of high levels of CO 2 on the electrochemical behavior and the enzymatic and non‐enzymatic antioxidant systems in black and white table grapes…

2019

[Bakghround]: In this study, we analyzed the effect of the application of high levels of CO2 (20 kPa CO2  + 20 kPa O2  + 60 kPa N2 ) for 3 days at low temperature on a white table-grape cultivar (Superior Seedless) in comparison with a black one (cv. Autumn Royal) in terms of quality parameters. We also used a solid-state voltammetry methodology to analyze the effect of the 3-day gaseous treatment in berry tissues from both cultivars in the first stage of storage. We determined the role of the non-enzymatic (total phenols, total anthocyanins, and antioxidant activity) and the enzymatic antioxidant (catalase (GCAT), ascorbate peroxidase (VcAPX) gene expression) systems in the behaviors of bo…

AntioxidantTotal phenolics030309 nutrition & dieteticsTotal anthocyaninsmedicine.medical_treatmentBerryengineering.material03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologymedicineFood sciencePhenolsCultivar0303 health sciencesNutrition and DieteticsbiologyPulp (paper)fungiTable grapeSolid state voltammetryfood and beverages04 agricultural and veterinary sciencesCatalase040401 food sciencechemistryCatalaseVitis viniferabiology.proteinengineeringAscorbate peroxidaseAgronomy and Crop ScienceFood ScienceBiotechnologyPeroxidaseJournal of the Science of Food and Agriculture
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In vitro bioaccessibility, transepithelial transport and antioxidant activity of Urtica dioica L. phenolic compounds in nettle based food products

2016

Nettle (Urtica dioica L.) is a well-known plant with a wide historical background use of stems, roots and leaves. Nettle leaves are an excellent source of phenolic compounds, principally 3-caffeoylquinic acid (3-CQA), caffeoylmalic acid (CMA) and rutin. The aim of this work was to evaluate the bioaccessibility (BAC), the bioavailability (BAV) and the antioxidant activity of nettle phenolic compounds present in foods and supplements. The BAC of nettle phenolics was evaluated with an in vitro dynamic digestion of real food matrices: the type of food matrix and chemical characteristic affected the kinetics of release and solubilization, with the highest BAC after duodenal digestion. A study of…

Antioxidantfood.ingredientFree Radicalsmedicine.medical_treatmentphenolicsBiological AvailabilityAntioxidantsNOchemistry.chemical_compoundRutinnettle phenolics HPLC-MS0404 agricultural biotechnologyfoodSuperoxidesmedicineHumansFood scienceUrtica dioicaUrticaUrtica dioicaBiological Transport04 agricultural and veterinary sciencesGeneral Medicinenettle040401 food scienceCaffeoylmalic acidBioavailabilityHPLC-MSBiochemistrychemistryFermentationCaco-2 CellsDigestionFood AnalysisFood Science
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Alternariol-induced cytotoxicity in Caco-2 cells. Protective effect of the phenolic fraction from virgin olive oil.

2014

The extra virgin olive oil (EVOO) has been associated to antioxidant effects. The mycotoxin alternariol (AOH) can contaminate olives. The aims of this work were to determine the cytotoxic effects and reactive oxygen species (ROS) produced by AOH, tyrosol and oleuropein (two polyphenols of olive oil) and a real EVOO extract in Caco-2 cells. The MTT assay and the ROS production by the H2-DCFDA probe were used. Results demonstrated that AOH reduces cellular proliferation depending on concentration, whereas tyrosol and oleuropein did not (12.5-100 μM). The combination of AOH + oleuropein (50 μM) increased cell proliferation (24%) whereas, AOH + tyrosol decreased (47%) it. Besides, AOH increased…

Antioxidantmedicine.medical_treatmentAlternariolAlternariol; Caco-2 cells; Cytotoxic and cytoprotective effect; Extra virgin olive oil; Phenolic compounds; ROS generationTetrazolium SaltsToxicologychemistry.chemical_compoundLactonesPhenolsOleuropeinExtra virgin olive oilmedicineHumansPlant OilsMTT assayPhenolsOlive OilCell Proliferationchemistry.chemical_classificationReactive oxygen speciesAnalysis of VariancePlant ExtractsPhenolic compoundsTyrosolAlternariolThiazoleschemistryBiochemistryPolyphenolROS generationCaco-2 CellsReactive Oxygen SpeciesCytotoxic and cytoprotective effectToxicon : official journal of the International Society on Toxinology
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Screening of antioxidant potentials and bioactive properties of the extracts obtained from two Centaurea L. species (C. kroumirensis coss. and C. sic…

2020

Herbal medicines, dietary supplements, or infusions with health promoting effects can note strong consumer demand. Hence, researchers and scientists have been increasingly focusing on the promotion of medicinal plants. In this respect, the present study has the evaluation of the biological properties of different extracts (hexane, chloroform, methanol, ultrasonic, essential oil, and supercritical) obtained from two Centaurea species (C. kroumirensis (Coss.) and C. sicula L. subsp sicula) as purpose. Antioxidative activities were assessed by in vitro assays including total phenolic content, free radical scavenging assay and ferric ion reducing power. Among the fourteen extracts examined, the…

Antioxidantphenolicsmedicine.medical_treatmentSonicationmedicine.disease_causelcsh:Technology01 natural scienceslaw.inventionProtective effectlcsh:Chemistrychemistry.chemical_compound0404 agricultural biotechnologyNutraceutical<i>Centaurea</i> spp.lawmedicineGeneral Materials ScienceFood scienceHydrogen peroxideMedicinal plantslcsh:QH301-705.5InstrumentationEssential oilFluid Flow and Transfer Processesbiologylcsh:TProcess Chemistry and TechnologyGeneral Engineering04 agricultural and veterinary sciencesbiology.organism_classification040401 food sciencelcsh:QC1-9990104 chemical sciencesComputer Science ApplicationsPlant extract010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999chemistryPhenoliclcsh:TA1-2040CentaureaCentaurea sppAntioxidantlcsh:Engineering (General). Civil engineering (General)lcsh:PhysicsOxidative stress
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Authentication of phacelia honeys (Phacelia tanacetifolia) based on a combination of HPLC and HPTLC analyses as well as spectrophotometric measuremen…

2019

Abstract The growing interest in the quality of honey affects customer preferences and consumption trends. Generally, monofloral honeys are more expensive than multifloral honeys, and the price strictly depends on its botanical origin. The increasing popularity of a variety of monofloral brands has led to the increasing number of adulterations and therefore for the need to develop new analytical methods for assessing honey authenticity. The purpose of the present study was to develop a method for the authentication of phacelia honeys on the basis of HPLC and HPTLC analyses and spectrophotometry. The results obtained by spectrophotometric analysis indicated significant differences only betwe…

Authentication of monofloral honeysbiologyHigh-performance thin-layer chromatographyPhacelia honeyContext (language use)biology.organism_classificationmedicine.disease_causeHigh-performance liquid chromatographyHoney samplesPhenolic compoundsHigh-performance liquid chromatographyPhacelia tanacetifoliaPhaceliaPollenmedicineFood scienceFood ScienceMathematicsLWT
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Pulsed electric fields (PEF), pressurized liquid extraction (PLE) and combined PEF + PLE process evaluation: Effects on Spirulina microstructure, bio…

2022

This study aims at evaluating the impact of different processes-pulsed electric fields (PEF), pressurized liquid extraction (PLE) and a multistep process combining PEF + PLE on the yield of antioxidant compounds (protein, polyphenols, chlorophyll a, chlorophyll b, and carotenoids) from Spirulina. Firstly, the effects of PEF or PLE treatment on the extraction yield of Spirulina biomolecules were evaluated. To further increase the extraction yield, PEF + PLE was used, as an innovative extraction approach. The results showed that PEF + PLE greatly improved the extraction yield compared with the PEF or PLE treatments alone. Compared with Folch extraction (conventional control technique), PEF + …

BiomoleculesTriple TOF-LC-MS-MSPhenolic profileGeneral Chemistryrespiratory systemPulsed electric fields (PEF)Pressurized liquid extraction (PLE)Industrial and Manufacturing EngineeringAntioxidantsrespiratory tract diseasesimmune system diseasesAlguesMicroalgaeCell structureFood Sciencecirculatory and respiratory physiologyInnovative Food Science & Emerging Technologies
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