Search results for "phenomena"
showing 10 items of 8379 documents
Two different posterior-stabilized mobile-bearing TKA designs: navigator evaluation of intraoperative kinematic differences
2020
Purpose: The purpose of this study was to compare two types of posterior-stabilized (PS) mobile-bearing (MB) total knee arthroplasties (TKAs). The hypothesis was that no major differences were going to be found among the two TKA designs. Methods: Two cohorts of patients who were divided according to implant design (Cohort A, new design gradually reducing radius PS MB TKA; Cohort B, traditional dual-radius PS MB TKA) were analyzed by means of intraoperative navigation. All operations were guided by a non-image-based navigation system that recorded relative femoral and tibial positions in native and implanted knees during the following kinematic tests: passive range of motion (PROM), varus–va…
Kinematics of the patellofemoral joint. Investigations on a computer model with reference to patellar fractures.
1990
Patellofemoral kinematics were studied on a computer model. The articulating point of the patella moves from distal to proximal during flexion, until the quadriceps tendon starts to turn around the femur tendo-femoral gliding. The pattern of patellofemoral movement consists of a gliding and rolling component, the latter at its maximum at the beginning of flexion. The pathway of the instant centers of motion moves from dorsal to ventral during flexion. Stress analysis shows that the contact area is at all times the area of maximum bending stress. The distal part of the patella is the part with mechanical stress at all angles of flexion. The conclusions to be drawn for treatment are that frac…
Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs).
2013
Abstract Inhibitors of Apoptosis (IAPs) are a family of proteins with various biological functions including regulation of innate immunity and inflammation, cell proliferation, cell migration and apoptosis. They are characterized by the presence of at least one N-terminal baculoviral IAP repeat (BIR) domain involved in protein-protein interaction. Most of them also contain a C-terminal RING domain conferring an E3-ubiquitin ligase activity. In drosophila, IAPs are essential to ensure cell survival, preventing the uncontrolled activation of the apoptotic protease caspases. In mammals, IAPs can also regulate apoptosis through controlling caspase activity and caspase-activating platform format…
Hippocampal event-related potentials to pitch deviances in an auditory oddball situation in the cat: experiment I.
1995
Hippocampal event-related potentials (ERP) in the areas CA1, CA3, and dentate fascia (Df) were recorded in cats during an oddball situation when pitch deviant tones occurred in a series of standard tones. When difference waves were calculated by subtracting ERPs to the standard tones from those to the deviant tones, no clear N40d, corresponding to a cat analogue of the human mismatch negativity (MMN) observed in earlier studies, could be detected. Instead, a prominent later negativity (N130d) was observed. A possible extra-hippocampal source of the process reflected by the MMN-like negativity, and a relation between an orienting response (OR) and the N130d are discussed.
Endocannabinoid Role in Synaptic Plasticity and Learning
2009
Endocannabinoids have recently emerged as versatile modulators of synaptic transmission and can act as retrograde neurotransmitters. As they cannot be stored in synaptic vesicles, endocannabinoid signaling is believed to start ‘on-demand,’ via a stimulus-dependent synthesis from membranous precursors at the postsynaptic site. After synthesis, endocannabinoids bind presynaptically to cannabinoid type 1 (CB1) receptors, leading to a short- or long-term suppression of neurotransmitter release. CB1 receptors are present in a plethora of different synaptic connections in the brain. Electrophysiological and behavioral analyses of mutant mice lacking CB1 receptors and of pharmacologically treated …
Pasyjne fenomeny mistyczne
2019
W doświadczeniach mistyków Kościoła ważne miejsce zajmuje fakt ich partycypacji w Męce Jezusa Chrystusa. Mistycy mogą otrzymać dary niewidzialnego przebicia serca i niewidzialnych stygmatów, również widzialnego udziału w biczowaniu, w ukoronowaniu cierniem i w ukrzyżowaniu Zbawiciela, co przyjmuje formę faktycznego przebicia ich dłoni, stóp i serca. Dopełnieniem są zjawiska krwawego potu i krwawych obrazów i napisów. Tak więc fenomeny pasyjne im udzielone są rzeczywistym odbiciem tajemnic Golgoty. Ich życie, przybiera formę żywej księgi pamięci o cenie Zbawienia, którą Jezus Chrystus zapłacił na drzewie Krzyża.
Women Scientists Who Made Nuclear Astrophysics
2019
Female role models reduce the impact on women of stereotype threat, i.e. of being at risk of conforming to a negative stereotype about one’s social, gender, or racial group (Fine in Delusion of Gender. W.W. Norton & Co. NY, p. 36, 2010 [1]; Steele and Aronson in J Pers Soc Psychol 69:797–811, 1995 [2]). This can lead women scientists to underperform or to leave their scientific career because of negative stereotypes such as, not being as talented or as interested in science as men. Sadly, history rarely provides role models for women scientists; instead, it often renders these women invisible (CafeBabel Homepage [3]). In response to this situation, we present a selection of twelve outst…
Observation of Astrophysical Neutrinos in Four Years of IceCube Data
2015
The spectrum of cosmic rays includes the most energetic particles ever observed. The mechanism of their acceleration and their sources are, however, still mostly unknown. Observing astrophysical neutrinos can help solve this problem. This update extends the data-taking period by one more year to four years from 2010 to 2014 for a total livetime of 1347 days.
IceCube-22 Solar WIMP Data: Searching for Muon Neutrinos from Dark Matter Annihilations in the Sun
2009
Relic dark matter in the galactic halo may become gravitationally trapped in the Sun and accumulate in its center, where it can annihilate each other, producing standard model particles, which may decay creating neutrinos. A search was performed using data from the IceCube detector in its 22 string configuration. The experimental dataset consists of 104.26 days livetime, corresponding to a set of runs recorded during the period when the Sun was below the horizon at the South Pole, between March 21st and September 23rd.
Astrophysical muon neutrino flux in the northern sky with 2 years of IceCube data
2015
Results from the IceCube Neutrino Observatory have recently provided compelling evidence for the existence of a high energy astrophysical neutrino flux utilizing a dominantly Southern Hemisphere data set consisting primarily of νe and ντ charged-current and neutral-current (cascade) neutrino interactions. Additionally, a fit for an astrophysical flux with an arbitrary spectral index is performed.