Search results for "phospholipides"

showing 2 items of 2 documents

Physico-chimie des lipopolysaccharides et réponse inflammatoire : rôle des lipoprotéines

2014

LPS is a potent bacterial pro-inflammatory agent, consisting of hydrophilic, polysaccharide part and of a lipid A which is considered like active moiety. Nevertheless, the O chain of LPS influences their aggregation in aqueous media. Therefore, our goal has been to determine the role of O chain on the LPS biological and physiopathological effects. Our work was organized according to three main axes, and led to the following findings :- development of a new LPS assay by LC-MS/MS. The combination of this new technique with LAL test allowed us to calculate an inactivation ratio which reflects the ability of host organism to inactivate LPS, especially through their transfer to HDL by PLTP. The …

Innate immunityInflammationImmunité innéeTLR4 (Toll-Like Receptor 4)Lipopolysaccharide (LPS)Monocyte[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]Lipide ALipoprotéinePhosphoLipid Transfer Protein (PLTP)Aggregation[ SDV.BBM.BC ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]Agrégationlipids (amino acids peptides and proteins)[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]LC-MS/MS assayDosage LC-MS/MSLipoprotein[SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Protéine de Transfert des Phospholipides (PLTP)
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Evaluation of the toxicity of mussels from 2 sites of the Moroccan Atlantic Coast (Jorf Lasfar and Oualidia) used as bioindicators of contamination :…

2012

Toxic substances generated by various human activities are spilled on different area of the Moroccan coast. Shellfishes can concentrate pollutants and have some adverse effects on human health through the food chain. Despite the strengthening of food safety rules, the involvement of chemical pollution of food on metabolic disorders is not known. To predict the impact of pollutants on the aquatic ecosystem and human health, the development of appropriate biomonitoring tools is required.We quantified heavy metals (Cd, Cr and Pb) in mussels (Mytilus galloprovincialis) from two sites of Moroccan Atlantic coast (industrial site Jorf Lasfar (JL) and touristic site Oualidia (OL)) due to the proxim…

Lipides (acides grasphytosterolsLipids (fatty acidsCytométrie en flux[ SDV.TOX.ECO ] Life Sciences [q-bio]/Toxicology/EcotoxicologyCytomicToxicologie (in vivo[ SDV.BBM.BC ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]Β pancreatic murines (MIN-6) cellsMusselsin vitro)Flow cytometryMicroscopie[SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM][SDV.BC] Life Sciences [q-bio]/Cellular BiologyphospholipidsMoulesMétaux lourdsMicroscopyChromatography[SDV.TOX.ECO] Life Sciences [q-bio]/Toxicology/Ecotoxicology[ SDV.BC ] Life Sciences [q-bio]/Cellular BiologycholesterolToxicology (in vivoHeavy metalsCytomiqueChromatographieoxysterolsCellules β pancréatiques murines (MIN-6)phospholipides
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