Search results for "phylogeny"

showing 10 items of 1398 documents

An outbreak of HBV and HCV infection in a paediatric oncology ward: Epidemiological investigations and prevention of further spread

2003

Hospital-acquired hepatitis B (HBV) and C virus (HCV) infections continue to occur despite increased awareness of this problem among the medical community. One hundred six patients were infected in a haematology oncology ward for children, over the time period 1996 to 2000. Serum samples from 45 such patients and 3 from infected medical personnel were used for nucleic acid amplification. HBV core, as well as HCV core and hypervariable region 1 (HVR1) nucleotide sequences, were analysed by phylogenetic tree analysis, in order to characterise the epidemiological pattern of viral transmission on the ward. Samples from 32 patients were positive for HBV-DNA or HCV-RNA by PCR. Ten patients were p…

Hepatitis B virusmedicine.medical_specialtyAdolescentMolecular Sequence DataHepacivirusmedicine.disease_causePediatricsPolymerase Chain ReactionDisease OutbreaksFlaviviridaeOncology Service HospitalVirologyEpidemiologymedicineHumansInfection controlChildPhylogenyHepatitis B virusCross InfectionbiologyTransmission (medicine)business.industryIncidence (epidemiology)virus diseasesSequence Analysis DNAHepatitis BHepatitis Bmedicine.diseasebiology.organism_classificationHepatitis CVirologydigestive system diseasesInfectious DiseasesChild PreschoolDNA ViralRNA ViralViral diseasebusinessJournal of Medical Virology
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Correction: Phylogeny of the Eurasian Wren Nannus troglodytes (Aves: Passeriformes: Troglodytidae) reveals deep and complex diversification patterns …

2020

The Mediterranean Basin represents a Global Biodiversity Hotspot where many organisms show high inter- and intraspecific differentiation. Extant phylogeographic patterns of terrestrial circum-Mediterranean faunas were mainly shaped through Pleistocene range shifts and range fragmentations due to retreat into different glacial refugia. Thus, several extant Mediterranean bird species have diversified by surviving glaciations in different hospitable refugia and subsequently expanded their distribution ranges during the Holocene. Such a scenario was also suggested for the Eurasian Wren (Nannus troglodytes) despite the lack of genetic data for most Mediterranean subspecies. Our phylogenetic mult…

HeredityBiochemistryGeographical LocationsSongbirdsPleistocene EpochAfrica NorthernEnergy-Producing OrganellesPhylogenyData ManagementMultidisciplinaryQuaternary PeriodGeographyFossilsQRPhylogenetic AnalysisGeologyBiodiversityBiological EvolutionFossil CalibrationMitochondriaPhylogeneticsEuropeGenetic MappingPhylogeographyBiogeographyMedicineCellular Structures and OrganellesResearch ArticleGenetic MarkersComputer and Information SciencesMitochondria ; Fossil calibration ; Haplotypes ; Europe ; Phylogenetic analysis ; Phylogeography ; Paleogenetics ; Pleistocene epochScienceBioenergeticsDNA MitochondrialGeneticsAnimalsEvolutionary SystematicsTaxonomyEvolutionary BiologyPopulation BiologyEcology and Environmental SciencesBiology and Life SciencesPaleontologyCorrectionGenetic VariationGeologic TimeCell BiologyHaplotypesPeople and PlacesEarth SciencesCenozoic EraPaleogeneticsPopulation Genetics
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Intraspecific and within-isolate sequence variation in the ITS rRNA gene region of Pythium mercuriale sp. nov. (Pythiaceae)

2008

Belbahri, Lassaad et al.

HeterozygoteNuclear geneGenotypeMolecular Sequence DataPythiumBiologyDNA RibosomalMicrobiologyDNA AlgalPeptide Elongation Factor 1Intergenic regionTubulinPhylogeneticsDNA Ribosomal SpacerGeneticsCluster AnalysisPythiumInternal transcribed spacerMolecular BiologyAllelesPhylogenyGeneticsPolymorphism GeneticPhylogenetic treeAlgal ProteinsGenes rRNASequence Analysis DNARibosomal RNAbiology.organism_classificationPythiaceaePhenotype
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A comparative analysis of genetic variation in rootstocks and scions of old olive trees – a window into the history of olive cultivation practices an…

2014

Background Past clonal propagation of olive trees is intimately linked to grafting. However, evidence on grafting in ancient trees is scarce, and not much is known about the source of plant material used for rootstocks. Here, the Simple Sequence Repeat (SSR) marker technique was used to study genetic diversity of rootstocks and scions in ancient olive trees from the Levant and its implications for past cultivation of olives. Leaf samples were collected from tree canopies (scions) and shoots growing from the trunk base (suckers). A total of 310 trees were sampled in 32 groves and analyzed with 14 SSR markers. Results In 82.7% of the trees in which both scion and suckers could be genotyped, t…

HeterozygotePlant ScienceBiologyPlant RootsTreesDomesticationOleaparasitic diseasesGenetic variationBotanySuckerCultivarIsraelMicrosatellitesPropagationAllelesPhylogenyPrincipal Component AnalysisGenetic diversityGraftingGeographyGenetic VariationOlive treesGenetic distanceGenetic LociGenetic markerOlive cultivarsRootstockPlant ShootsResearch ArticleMicrosatellite RepeatsBMC Plant Biology
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Evolutionary history of the OmpR/IIIA family of signal transduction two component systems in Lactobacillaceae and Leuconostocaceae

2011

15 pages, 3 tables, 7 figures.

Histidine KinaseEvolutionMolecular Sequence DataSignal transductionEvolution MolecularBacterial ProteinsPhylogeneticsQH359-425Lactic acid bacteriaAmino Acid SequenceGeneEcology Evolution Behavior and SystematicsPhylogenyGeneticsTwo component systemLeuconostocaceaebiologyPhylogenetic treeLactobacillalesfungiLactobacillaceaebiology.organism_classificationTwo-component regulatory systemResponse regulatorLactobacillaceaeMultigene FamilyLeuconostocaceaeProtein KinasesSequence AlignmentOmpR/IIIA familyResearch Article
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Cellular and tissue expression of DAPIT, a phylogenetically conserved peptide

2011

DAPIT (Diabetes Associated Protein in Insulin-sensitive Tissues) is a small, phylogenetically conserved, 58 amino acid peptide that was previously shown to be down-regulated at mRNA level in insulin-sensitive tissues of type 1 diabetes rats. In this study we characterize a custom made antibody against DAPIT and confirm the mitochondrial presence of DAPIT on cellular level. We also show that DAPIT is localized in lysosomes of HUVEC and HEK 293T cells. In addition, we describe the histological expression of DAPIT in several tissues of rat and man and show that it is highly expressed especially in cells with high aerobic metabolism and epithelial cells related to active transport of nutrients …

HistologyCellular respirationProtein subunitBiophysicsPeptideV-ATPaseBiologyMitochondrionAntibodiesMitochondrial ProteinsHuman Umbilical Vein Endothelial CellsV-ATPaseAnimalsHumansmitochondrionta315lcsh:QH301-705.5PhylogenyDAPIT mitochondrion V-ATPase type 1 diabeteschemistry.chemical_classificationRegulation of gene expressionOriginal Papertype 1 diabetes.HEK 293 cellsMembrane ProteinsCell BiologyProton PumpsCell biologyMitochondriaRatsHEK293 CellsMembrane proteinchemistryBiochemistryGene Expression Regulationlcsh:Biology (General)Organ SpecificityLysosomesDAPITEuropean Journal of Histochemistry
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Sequence, evolution and tissue expression patterns of an epidermal type I keratin from the shark Scyliorhinus stellaris.

2004

From the shark Scyliorhinus stellaris we cloned and sequenced a cDNA encoding a novel type I keratin, termed SstK10. By MALDI-MS peptide mass fingerprinting of cytoskeletal proteins separated on polyacrylamide gels, we assigned SstK10 to a 46-kDa protein which is the major epidermal type I (“IE”) keratin in this fish and is specifically expressed in stratified epithelia. In a phylogenetic tree based on type I keratin sequences and with lamprey keratins applied as outgroup, SstK10 branches off in a rather basal position. This tree strongly supports the concept that teleost keratins and tetrapod keratins resulted from two independent gene radiation processes. The only exception is human K18 b…

HistologyDNA ComplementaryType I keratinMolecular Sequence Datamacromolecular substancesMass SpectrometryPathology and Forensic MedicineSequence Analysis Proteinbiology.animalKeratinAnimalsAmino Acid SequenceCloning MolecularPhylogenychemistry.chemical_classificationintegumentary systemPhylogenetic treebiologyLampreyVertebrateCell BiologyGeneral MedicineGnathostomataKeratin 6AAnatomybiology.organism_classificationImmunohistochemistryCell biologychemistryEpidermal CellsGene Expression RegulationOrgan SpecificitySharksKeratinsElectrophoresis Polyacrylamide GelEpidermisScyliorhinus stellarisEuropean journal of cell biology
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Vimentin and desmin of a cartilaginous fish, the shark Scyliorhinus stellaris: Sequence, expression patterns and in vitro assembly

2002

In the shark Scyliorhinus stellaris we have biochemically identified and cDNA-cloned orthologs of human vimentin and desmin, SstV and SstD, as deduced from immunoblotting and sequence alignment with teleost, frog and human vimentin and desmin, respectively. This allowed us to further clarify the relationship of previously identified lower vertebrate intermediate filament proteins to mammalian vimentin and desmin. Immunofluorescence microscopy with antibodies H5 and VIM13.2 showed vimentin expression in shark eye and brain and absence in epithelia, which resembles the situation in higher vertebrates. In addition, SstV is expressed in many mesenchymal cell types which corresponds to the case …

HistologyNeurofilamentMolecular Sequence DataIntermediate FilamentsGene ExpressionVimentinmacromolecular substancesDesminPathology and Forensic MedicineEvolution MolecularProtein filamentKeratinAnimalsVimentinIntermediate filamentPhylogenychemistry.chemical_classificationSequence Homology Amino AcidbiologyProtein primary structureCell BiologyGeneral Medicinebiology.organism_classificationMolecular biologyMicroscopy ElectronchemistrySharksbiology.proteinDesminScyliorhinus stellarisEuropean Journal of Cell Biology
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Differentiation capacity of epithelial cells in the sponge Suberites domuncula.

2004

Sponges (phylum Porifera) represent the oldest metazoans. Their characteristic metazoan adhesion molecules and transcription factors enable them to establish a complex "Bauplan" ; three major differentiated cell types (epithelial cells, skeletal cells/sclerocytes, and contractile cells) can be distinguished. Since no molecular markers are as yet available to distinguish these somatic cells or the corresponding embryonic cells from which they originate, we have selected the following three genes for their characterization: noggin (a signaling molecule in development), a caspase that encodes an apoptotic molecule, and silicatein. Silicatein is an enzyme that is involved in the synthesis of si…

HistologySuberites domuncula; sponges; cell differentiationCellular differentiationMolecular Sequence DataPinacodermBiologyPathology and Forensic MedicineEvolution MolecularDemospongeMesohylAnimalsAmino Acid SequenceNogginCloning MolecularPhylogenySclerocyteCell AggregationSequence Homology Amino AcidSilicatesProteinsCell DifferentiationCell BiologyAnatomybiology.organism_classificationCell biologySuberites domunculaSpongeCaspasesCarrier ProteinsSuberitesCell and tissue research
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Sponge Bcl-2 homologous protein (BHP2-GC) confers distinct stress resistance to human HEK-293 cells

2001

It is established that sponges, the phylogenetically oldest still extant phylum of Metazoa, possess key molecules of the apoptotic pathways, that is members from the Bcl-2 family and a pro-apoptotic molecule with death domains. Here we report on transfection studies of human cells with a sponge gene, GCBHP2. Sponge tissue was exposed to heat shock and tributyltin, which caused an upregulation of gene expression of GCBHP2. The cDNA GCBHP2 was introduced into human HEK-293 cells and mouse NIH-3T3 cells; the stable transfection was confirmed by the identification of the transcripts, by Western blotting as well as by immunofluorescence using antibodies raised against the recombinant polypeptide…

Hot Temperatureanimal structuresCell SurvivalvirusesMolecular Sequence DataDrug ResistanceApoptosisAntibodiesCell LineMiceComplementary DNAGene expressionAnimalsHumansAmino Acid SequenceRNA MessengerCloning MolecularMolecular BiologyPhylogenySequence Homology Amino AcidbiologyCaspase 3ChemistryfungiHEK 293 cellsCell BiologyTransfectionbiology.organism_classificationMolecular biologyPoriferaProtein Structure TertiaryUp-RegulationEnzyme ActivationBlotSpongeProto-Oncogene Proteins c-bcl-2Cell cultureCaspasesembryonic structuresbiology.proteinTrialkyltin CompoundsAntibodySequence AlignmentHeat-Shock ResponseCell Death & Differentiation
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