Search results for "pig"
showing 10 items of 2235 documents
Reflexividad y narratividad en Ricardo Piglia: de Macedonio a Fitzgerald
2013
Resumen: Este articulo analiza algunos rasgos de la narrativa reciente del argentino Ricardo Piglia con relacion a las poeticas de Macedonio Fernandez y del estadounidense Francis Scott Fitzgerald. La primera parte trabaja la relacion conflictiva de Piglia con el llamado posmodernismo; la segunda parte explica el vinculo entre Piglia y Macedonio, a traves de la poetica de la autonomia de lo literario; la tercera parte aborda la relacion con Fitzgerald, por medio de un analisis de sus respectivas busquedas de formas narrativas, para concluir en una cuarta parte ciertos cambios dentro de la propia obra novelesca de Piglia. Palabras clave: Piglia, Fitzgerald, Macedonio, posmodernismo, narrativ…
Rewriting antiquity, renewing Rome. The Identity of the Eternal City through Visual Art, Monumental Inscriptions and the Mirabilia
2011
AbstractDuring the eleventh and twelfth centuries the Church began a process of renovation (renovatio) and the city of Rome was given new meanings. Antiquity is part of the identity of the Eternal City; the reuse or reframing of aspects of antiquity inevitably transformed the image of Rome. Public spaces, architecture and objects were given new Christian readings. Inscriptions, present both in sacred and secular settings, played an important role. A similar rewriting can also be found in travel literature and descriptions of the city, such as in the Mirabilia urbis Rome, where ancient monuments were re-interpreted to demonstrate the superiority of Christianity. Inscriptions were used as sym…
UV-C as an Efficient Means to Combat Biofilm Formation in Cultural Heritage Monument. Biodiversity and Impact on Prehistoric Pigments?
2018
Caves are considered oligotrophic habitats exhibiting constant temperature and relative humidity throughout the year. While darkness inhibits photosynthetic microorganism growth, introducing artificial lights to promote touristic activity can induce algae and cyanobacteria proliferation. Besides the aesthetic problem, microorganisms are responsible of physical and chemical degradation of limestone wall with possibly a degradation of prehistoric painting of cultural value. In our studies, we identified lampenflora with new-generation sequencing (NGS) in five French show caves and also on a 180, 000 years old contaminated bear bones (Ursus deningeroides). Afterward, we attempted to find an ec…
Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescence
2020
AbstractTranscriptional regulation of DNA repair is of outmost importance for the restoration of DNA integrity upon genotoxic stress. Here we report that the potent environmental carcinogen benzo[a]pyrene (B[a]P) activates a cellular DNA damage response resulting in transcriptional repression of mismatch repair (MMR) genes (MSH2, MSH6, EXO1) and of RAD51, the central homologous recombination repair (HR) component, ultimately leading to downregulation of MMR and HR. B[a]P-induced gene repression is caused by abrogated E2F1 signalling. This occurs through proteasomal degradation of E2F1 in G2-arrested cells and downregulation of E2F1 mRNA expression in G1-arrested cells. Repression of E2F1-me…
The Effect of Vanadium on the Content of Chlorophyll, P-700 and Cytochrome f at Different Light Intensities in Chlorella fusca
1980
Summary Cells of Chlorella fusca, were grown in liquid medium supplemented ,vith O.2% glucose and varied concentrations of vanadium both at 5 different light intensities and in the dark. \Vith increasing concentrations of vanadium the content of chlorophyll, P-700 and cytochrome f increased as well, each, however, in a different way. At the saturating concentration of 20 µg vanadium per litre the pigment content per dry weight was double as high as that of the vanadium-free control; the ratio of chlorophyll a/chlorophyll b increased from 2.1 to 2.9. The content of P-700 at saturating vanadium concentration was four times higher than that of the control when based on dry weight and double as…
The Yeast RNA Polymerase II-associated Factor Iwr1p Is Involved in the Basal and Regulated Transcription of Specific Genes
2009
RNA polymerase II (RNA pol II) is a multisubunit enzyme that requires many auxiliary factors for its activity. Over the years, these factors have been identified using both biochemical and genetic approaches. Recently, the systematic characterization of protein complexes by tandem affinity purification and mass spectroscopy has allowed the identification of new components of well established complexes, including the RNA pol II holoenzyme. Using this approach, a novel and highly conserved factor, Iwr1p, that physically interacts with most of the RNA pol II subunits has been described in yeast. Here we show that Iwr1p genetically interacts with components of the basal transcription machinery …
Modification of the monoaminergic neurotransmitters in frontal cortex and hippocampus by dietary trans alpha linolenic acid in piglets
2002
International audience; The effect of partial isomerization of dietary α-linolenic acid on the monoaminergic neurotransmitters in piglets was studied. After feeding the animals for 14 days with diets containing or not trans α-linolenic acid, neurotransmitters related to the monoaminergic function were quantified in the frontal cortex and in the hippocampus. The partial isomerization of dietary α-linolenic acid resulted in increasing endogenous monoamine levels in the frontal cortex (+55% for dopamine) and was related to a very low incorporation of trans polyunsaturated fatty acids. However, feeding animals with a diet in which the imbalance generated by the isomerization of α-linolenic acid…
Transcription of genes in the biosynthetic pathway for fumonisin mycotoxins is epigenetically and differentially regulated in the fungal maize pathog…
2012
ABSTRACT When the fungal pathogen Gibberella moniliformis (anamorph, Fusarium verticillioides ) colonizes maize and maize-based products, it produces class B fumonisin (FB) mycotoxins, which are a significant threat to human and animal health. FB biosynthetic enzymes and accessory proteins are encoded by a set of clustered and cotranscribed genes collectively named FUM, whose molecular regulation is beginning to be unraveled by researchers. FB accumulation correlates with the amount of transcripts from the key FUM genes, FUM1 , FUM21 , and FUM8 . In fungi in general, gene expression is often partially controlled at the chromatin level in secondary metabolism; when this is the case, the deac…
Synthesis, chemical characterization, computational studies and biological activity of new DNA methyltransferases (DNMTs) specific inhibitor. Epigene…
2015
This work deals with the synthesis, the chemical characterization of dibutyltin(IV) complex of caffeic acid (Bu2Sn(IV)HCAF, caf1) and its cytotoxic action on tumor cells. The coordination environment at the tin center was investigated by FTIR, (119)Sn{(1)H} cross polarization magic angle spinning, electrospray ionization mass spectroscopy in the solid state and UV-vis, fluorescence and (1)H, (13)C and (119)Sn NMR spectroscopy in solution phases. Density functional theory study confirmed the proposed structures in solution phase and indicated the most probably stable conformation. The effects on viability of breast cancer MDA-MB231, colorectal cancer HCT116, hepatocellular carcinoma HepG2 an…
Sex-specific windows for high mRNA expression of DNA methyltransferases 1 and 3A and methyl-CpG-binding domain proteins 2 and 4 in human fetal gonads
2006
DNA methyltransferases (DNMTs) and 5-methyl-CpG-binding domain proteins (MBDs) are involved in the acquisition of parent-specific epigenetic modifications in human male and female germ cells. Reverse Northern blot analyses demonstrated sex-specific differences in mRNA expression for the maintenance DNMT1 and the de novo DNMT3A in developing testis and ovary. In fetal testis DNMT1 and DNMT3A expression peaked in mitotically arrested spermatogonia around 21 weeks gestation. In fetal ovary transcriptional upregulation of DNMT1 and DNMT3A occurred during a very brief period at 16 weeks gestation, when the oocytes proceeded through meiotic prophase. Fetal gonads showed several fold higher DNMT3A…