Search results for "pilot projects"
showing 10 items of 488 documents
Administration of a Synbiotic to Free-Living Elderly and Evaluation of Serum Cytokines. A Pilot Study
2010
Ten free-living elderly were administered with a synbiotic [fermented milk containing Lactobacillus rhamnosus Gorbach and Goldin (LGG)] and oligofructose as a prebiotic for one month. Serum cytokines were evaluated before (T(0)) and after (T(1)) synbiotic administration. At T(0), values of Interleukin (IL)-12, IL-6, IL-10, IL-1beta and Tumor Necrosis Factor (TNF)-alpha were lower than normal controls, with the exception of IL-8, thus confirming previous results on the impairment of both innate and adaptive responses in elderly. At T(1), the synbiotic was able to significantly increase, depressed values of IL-1, IL-6 and IL-8 with a trend to a modest increase for the restant cytokines. In co…
Peri-implant parameters in head and neck reconstruction: influence of extraoral skin or intraoral mucosa.
2009
Objective: This study is designed to assess dental implants supporting overdentures in edentulous patients with operated head and neck malignancies using parameters to detect peri-implant disease. Material and methods: Thirty-four implants supporting overdentures in 34 oral cancer patients were examined. Clinical parameters [plaque index, probing depth, bleeding on probing (BOP), origin of peri-implant soft tissue, and amount of irradiation] were recorded, and microbiological identification of periodontal pathogens was carried out by DNA–DNA hybridization. To identify yeast species, the samples were cultivated on Sabouraud agar plates and subsequently identified by API 20C AUX plates. An im…
Fast and low-cost decentralized surveillance of transmission of tuberculosis based on strain-specific PCRs tailored from whole genome sequencing data…
2015
Molecular epidemiology has transformed our knowledge of how tuberculosis (TB) is transmitted. Whole genome sequencing (WGS) has reached unprecedented levels of accuracy. However, it has increased technical requirements and costs, and analysis of data delays results. Our objective was to find a way to reconcile speed and ease of implementation with the high resolution of WGS. The targeted regional allele-specific oligonucleotide PCR (TRAP) assay presented here is based on allele-specific PCR targeting strain-specific single nucleotide polymorphisms, identified from WGS, and makes it possible to track actively transmitted Mycobacterium tuberculosis strains. A TRAP assay was optimized to track…
Primary loading of palatal implants for orthodontic anchorage--a pilot animal study.
2006
Summary Objectives This study aimed at evaluating the clinical performance and osseointegration of short orthodontic implants immediately loaded with orthodontic forces. Material and methods The investigation was designed as an experimental animal study. Eight palatal implants of the Ortho-system® were immediately loaded with 100 cN after palatal insertion in 4 female german shepherd dogs. Xylene orange and calcein green were used for polychrome sequential labelling. Histological preparation utilized the cutting and grinding technique. Outcome variables were clinical implant success, histological osseointegration and bone-to-implant contact rates. Results All (8/8) implants were clinically …
Korkeakouludiplomi : kokeiluhankkeen seuranta- ja arviointitutkimuksen väliraportti
2015
Korkeakouludiplomi on opetus- ja kulttuuriministeriön käynnistämä koulutuskokeilu, jonka tarkoituksena on selvittää nykyisiä korkeakoulututkintoja suppeampien koulutusten käyttökelpoisuutta työelämän ja opiskelijoiden kannalta. Korkeakouludiplomikoulutus alkoi syksyllä 2014 pilottihankkeena Jyväskylän ammattikorkeakoulussa ainoana korkeakouluna Suomessa. Tämä julkaisu on väliraportti kokeilun seuranta- ja arviointitutkimuksesta. Siinä kerrotaan opiskelijavalinnasta, koulutuksen organisoinnista, opetussisällöistä ja pedagogista ratkaisuista sekä havainnoista koulutuksen alkuvaiheessa. Raportti perustuu koulutuksen järjestäjien haastatteluihin, raportteihin ja dokumentteihin sekä opiskelijo…
Is backward disequilibrium in the elderly caused by an abnormal perception of verticality? A pilot study
2007
International audience; OBJECTIVE: We hypothesised that backward disequilibrium (BD), defined by a posterior position of the centre of mass with respect to the base of support, could be caused by a backward tilt in the perception of verticality. METHODS: The relationship between BD, the perception of verticality, and the history of falls in 25 subjects aged 84.5+/-7.4 years was analysed. An original ordinal scale, the BD scale (BDS), was used to quantify BD. Postural (PV) and haptic verticals (HV) were measured in sagittal plane. RESULTS: BDS scores closely correlated with the number of falls (r = 0.81, p =10(-5)). The more the PV was tilted backward, the greater the BDS scores (r = -0.95, …
New Prospectives in the Delivery of Galantamine for Elderly Patients Using the IntelliDrug Intraoral Device: In Vivo Animal Studies
2009
The transbuccal delivery of drugs could assist several categories of chronic, especially elderly, patients in adhering to a correct dosage regimen. In particular, patients suffering from dementia have several difficulties in following the prescribed dosage, in addition to problems associated with swallowing tablets. Galantamine is currently used for treating patients with mild to moderate Alzheimer's-type dementia. The transbuccal delivery of this drug could be an interesting non- invasive and safe administration route. Several studies have been performed in vitro and ex vivo within the framework of a European Commission funded Project (IntelliDrug-FP6), aimed at developing a device which w…
Adaptation and implementation of the German social-emotional learning programme Papilio in Finland : A pilot study
2019
This study investigated the cross‐national adaptation and implementation of Papilio, a German social–emotional learning programme, in Finnish early childhood education and care (ECEC) centres. Papilio is a developmentally focused, scientifically based intervention programme focused on preventing behavioural problems and fostering social–emotional competence in children aged 3–7. The aim of this study was to investigate and evaluate the cross‐national adaptation and cross‐cultural adaptation and implementation of Papilio in the Finnish ECEC context. Results from qualitative interviews with one Finnish Papilio trainer, 11 early childhood education (ECE) teachers, two ECE special education tea…
Effects of pulsed electromagnetic fields on cognitive processes - a pilot study on pulsed field interference with cognitive regeneration.
2004
Background – Due to the ubiquitous use of cellular phones much has been speculated on secondary effects of electromagnetic irradiation emitted by those. Additionally, several studies have reported vegetative alterations as well as effects on the neuronal and molecular levels in humans. Here, using a psycho–physiological test paradigm, we examined effects of exposure to pulsed electromagnetic fields on cognitive performance. Materials and methods – In 11 volunteers, we tested cognitive processing under field exposure (GSM standard) and under field-free conditions. To examine the hypothesized effect of pulsed fields, we applied an auditory discrimination task and determined the participant's …
Modelling of hybrid moving bed biofilm reactors: a pilot plant experiment.
2007
In recent years there has been an increasing interest in the development of hybrid biofilm reactors, especially in the upgrading of existing WWTP that are no longer able to respect concentration limits. In fact, today's challenge is the achievement of a good aquatic state for the receiving water bodies according to the Water Framework Directive requirements, which indeed limit even more the continuous emissions, i.e. coming from WWTP. This paper presents the setting up of a mathematical model for the simulation of a hybrid MBBR system; the model calibration/validation has been carried out considering a field gathering campaign on an experimental pilot plant. The main goal is to gain insight…