Search results for "pine"
showing 10 items of 2022 documents
Cooked and raw. Fruits and seeds in the Iberian Palaeolithic
2022
Fruits, seeds, leaves and underground storage organs were all consumed by human groups during the Palaeolithic. These plant foodstuffs provided humans with minerals, vitamins and nutrients essential for optimal health. In this sense, fire control was a crucial human achievement since cooking allowed the physical and chemical modification of these elements by eliminating toxins, enhancing the digestion of foodstuffs and increasing their energy value. The use of fire during plant processing increases the potential preservation of archaeobotanical remains, as well. Based on the preserved plant elements and their characteristics, the chaîne opératoire of plant consumption can be reconstructed. …
Clinical and radiological features of Forestier's disease presenting with dysphagia
2018
Background Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier's disease, is a rheumatologic condition characterized by ossification of the spinal ligaments and tendons. Large anterior osteophytes are typically present in the lower cervical levels, while upper cervical ossification resulting in dysphagia is very rare. Methods Here, we presented a patient with Forestier's disease involving massive ossification of the anterior longitudinal ligament extending from C3 to C4 downward contributing to severe dysphagia. Results A 65-year-old male presented with cervical pain and dysphagia. The computed tomography of the cervical spine demonstrated massive anterior longitudinal …
The GABAergic effect of low doses of lorazepam on social behavior
2002
The aim of this work was to test the antiaggressive effects of lorazepam and to determine whether these effects were mediated by benzodiazepine receptors. In a first experiment, male mice were injected with lorazepam in a range of low doses (0.05, 0.1, 0.2, and 0.6 mg/kg) or saline solution. In a second experiment, 1 mg/kg of Ro 15-1788, a benzodiazepine receptor antagonist, and a saline solution were injected before the behavioral test. Results showed that 0.6 mg/kg of lorazepam was the only dose that decreased the total duration of threat ( P < .01) and social investigation ( P < .05) and that 1 mg/kg of Ro 15-1788 had no effects. In the third experiment, animals received two injec- tions…
Spatiotemporal and gender-specific parasitism in two species of gobiid fish
2018
Parasitism is considered a major selective force in natural host populations. Infections can decrease host condition and vigour, and potentially influence, for example, host population dynamics and behavior such as mate choice. We studied parasite infections of two common marine fish species, the sand goby (Pomatoschistus minutus) and the common goby (Pomatoschistus microps), in the brackish water Northern Baltic Sea. We were particularly interested in the occurrence of parasite taxa located in central sensory organs, such as eyes, potentially affecting fish behavior and mate choice. We found that both fish species harbored parasite communities dominated by taxa transmitted to fish through …
Benzodiazepine receptor interactions may be involved in the neurotoxicity of various penicillin derivatives
1980
The interaction of seven penicillin derivatives with specific [3H]flunitrazepam binding to benzodiazepine receptors was investigated. The affinities of the penicillins for benzodiazepine receptor seemed to depend on the lipophilia of the derivatives. The concentrations of the penicillins which inhibit specific [3H]flunitrazepam binding are consistent with penicillin levels found in the central nervous system of patients developing penicillin induced convulsions. The results suggest that penicillins inhibit GABAergic transmission not only at the GABA receptor, but also at the benzodiazepine receptor, which is thought to be part of a neuronal system facilitating GABAergic transmission. Both m…
Divergent Macroparasite Infections in Parapatric Swiss Lake-Stream Pairs of Threespine Stickleback (Gasterosteus aculeatus)
2015
Spatial heterogeneity in diversity and intensity of parasitism is a typical feature of most hostparasite interactions, but understanding of the evolutionary implications of such variation is limited. One possible outcome of infection heterogeneities is parasite-mediated divergent selection between host populations, ecotypes or species which may facilitate the process of ecological speciation. However, very few studies have described infections in populationpairs along the speciation continuum from low to moderate or high degree of genetic differentiation that would address the possibility of parasite-mediated divergent selection in the early stages of the speciation process. Here we provide…
The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes.
1998
The amino acid gamma-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotransmitter that mediates most of its effects through fast GABA-gated Cl(-)-channels (GABAAR). Molecular biology uncovered the complex subunit architecture of this receptor channel, in which a pentameric assembly derived from five of at least 17 mammalian subunits, grouped in the six classes alpha, beta, gamma, delta, sigma and epsilon, permits a vast number of putative receptor isoforms. The subunit composition of a particular receptor determines the specific effects of allosterical modulators of the GABAARs like benzodiazepines (BZs), barbiturates, steroids, some convulsants, polyvalent cations, and et…
Potential Functional Significance of Brain-Type and Muscle-Type Nitric Oxide Synthase I Expressed in Adventitia and Media of Rat Aorta
1999
Abstract —Skeletal muscle and myocardium express μNOS I, an elongated splice variant of neuronal-type nitric oxide (NO) synthase (NOS I), and NOS III, endothelial-type NO synthase, respectively. This study was designed to elucidate whether vascular smooth muscle also contains a constitutively expressed NO synthase isoform. In the rat, μNOS I contains an insert of 102 nucleotides after nucleotide 2865 of the cDNA, yielding a protein of 164 kd. Reverse transcription-polymerase chain reaction with primers flanking this insert and with insert-specific primers indicated that endothelium-denuded rat aorta expresses both brain-type NOS I and μNOS I. RNase protection analyses with an antisense RNA…
Synthesis and host properties of tetragonal Li2Mn2O4 and Li2Co0.4Mn1.6O4
2000
Abstract This paper presents synthesis and electrochemical properties of tetragonal lithium manganese dioxide, Li2Mn2O4 and its cobalt doped analogue Li2Co0.4Mn1.6O4. The materials are compared as host materials for lithium insertion and the behavior during the initial lithium extraction as well as on repeated cycling is presented. These materials show an initial lithium extraction capacity between 200 and 270 mAh/g. On repeated cycling, they are converted into spinel-like lattices with reversible capacities in the range 82–90 mAh/g. As they are chemically compatible with the manganese spinel, they will be well suited as additives compensating for the capacity loss during the initial formin…
Populetum pamiricae ass. nova – an endemic forest association to Pamir in Tajikistan (Middle Asia)
2015
Abstract The floristic structure, distribution and habitat requirements of a forest syntaxon, Populetum pamiricae ass. nova is described. The potential range of the Populetum pamiricae association comprises the mountains of eastern Tajikistan (Pamir Alai Mts), Kashgaria in western China (Kunlun Shan Mts) and north-eastern Afghanistan (Hindu Kush Mts) in Middle Asia. The biotope of this community comprises of high mountain river valleys situated at elevations between 2,500 and 3,200 m above sea level. Phytocoenoses of the Populetum pamiricae association are characterized by the apparent domination in the tree layer of a diagnostic species, Populus pamirica. The tree stand has a mean cover ar…