Search results for "plastica"

showing 10 items of 197 documents

Different Hydraulic Constructs to Optimize the Venous Drainage of DIEP Flaps in Breast Reconstruction: Decisional Algorithm and Review of the Literat…

2020

 Venous congestion is the most common perfusion-related complication of deep inferior epigastric artery perforator (DIEP) flap. Several hydraulic constructs can be created for venous superdrainage in case of flap venous engorgement or as a preventive measure. These can be classified based on the choice of the draining vein of the flap, either a second deep inferior epigastric vein (DIEV) or a superficial inferior epigastric vein (SIEV), and of the recipient vein, either a vein of the chest or the DIEV. Background Venous congestion is the most common perfusion-related complication of deep inferior epigastric artery perforator (DIEP) flap. Several hydraulic constructs can be created for venou…

MammaplastyreviewSettore MED/19 - Chirurgia PlasticaAnastomosissuperdrainageStandard anatomical positionDIEP flap superdrainage algorithm reviewDIEP flapDIEP flap; superdrainage; algorithm; reviewmedicineHumansVeinalgorithmbusiness.industryDeep Inferior Epigastric ArteryDIEP flapVenous drainageEpigastric ArteriesInferior epigastric veinmedicine.anatomical_structuremedicine.veincardiovascular systemDrainageSurgerybusinessBreast reconstructionPerforator FlapAlgorithmAlgorithms
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Characterization of Human γδ T Lymphocytes Infiltrating Primary Malignant Melanomas

2012

T lymphocytes are often induced naturally in melanoma patients and infiltrate tumors. Given that gamma delta T cells mediate antigen-specific killing of tumor cells, we studied the representation and the in vitro cytokine production and cytotoxic activity of tumor infiltrating gamma delta T cells from 74 patients with primary melanoma. We found that gamma delta T cells represent the major lymphocyte population infiltrating melanoma, and both V delta 1(+) and V delta 2(+) cells are involved. The majority of melanoma-infiltrating gamma delta cells showed effector memory and terminally-differentiated phenotypes and, accordingly, polyclonal gamma delta T cell lines obtained from tumor-infiltrat…

MelanomasCytotoxicity ImmunologicMaleRENAL-CELL CARCINOMA OVERCOMING IMMUNOLOGICAL-TOLERANCE METASTATIC MELANOMA TUMOR-CELLS PHASE-I MEVALONATE PATHWAY TARGETING CTLA-4 LYMPH-NODES IMMUNOTHERAPY CANCERAnatomy and PhysiologySkin NeoplasmsTUMOR-CELLSLymphocytemedicine.medical_treatmentT-LymphocytesSettore MED/19 - Chirurgia PlasticaTARGETING CTLA-4Interleukin 21T-Lymphocyte SubsetsImmune PhysiologyMETASTATIC MELANOMACytotoxic T cellIL-2 receptorSkin TumorsMelanomaOVERCOMING IMMUNOLOGICAL-TOLERANCEAged 80 and overMultidisciplinaryT CellsMelanomaMalignant MelanomaQRReceptors Antigen T-Cell gamma-deltaMiddle AgedCANCERPHASE-Imedicine.anatomical_structureCytokinePhenotypeOncologyCytokinesMedicineFemaleResearch ArticleTumor ImmunologyAdultScienceT cellImmune CellsImmunologyMalignant Skin NeoplasmsDermatologyBiologyImmunophenotypingImmune systemLymphocytes Tumor-InfiltratingmedicineHumansIMMUNOTHERAPYBiologyAgedNeoplasm StagingSettore MED/04 - Patologia GeneraleLYMPH-NODESCancers and NeoplasmsImmunologic Subspecialtiesmedicine.diseaseImmune SystemImmunologyOVERCOMING IMMUNOLOGICAL-TOLERANCE; METASTATIC MELANOMA; TUMOR-CELLS; PHASE-I; MEVALONATE PATHWAY; TARGETING CTLA-4; LYMPH-NODES; IMMUNOTHERAPY; CANCERClinical ImmunologyImmunologic MemoryMEVALONATE PATHWAYPLoS ONE
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Skewed Differentiation of Circulating Vγ9Vδ2 T Lymphocytes in Melanoma and Impact on Clinical Outcome

2016

OBJECTIVE:The aim of this study was to evaluate over time circulating γδ T lymphocytes in melanoma patients in terms of frequency, effector functions, and relationship with clinical stage and evolution, by comparing preoperative values to those obtained at a mean follow-up of 36 months or in the event of recurrence or disease progression, and to those of healthy controls. Also, we correlated the presence of tumor-infiltrating γδ T lymphocytes with clinical evolution of melanoma. RESULTS:Mean frequencies of circulating γδ T cells before and after melanoma removal were very similar and comparable to healthy subjects, but patients who progressed to stage III or IV showed a significantly decrea…

MelanomasMale0301 basic medicineSkin NeoplasmsCellular differentiationmedicine.medical_treatmentSettore MED/19 - Chirurgia Plasticalcsh:MedicineWhite Blood Cells0302 clinical medicineAnimal CellsMedicine and Health SciencesMedicineCytotoxic T cellStage (cooking)lcsh:ScienceMelanomaγδ T lymphocytes melanoma prognostic biomarkerCultured Tumor CellsAged 80 and overMultidisciplinaryT CellsEffectorMelanomaCell DifferentiationReceptors Antigen T-Cell gamma-deltaMiddle AgedPrognosisPhenotypeSurgical OncologyPhenotypeCytokineOncology030220 oncology & carcinogenesisCutaneous MelanomaMelanoma CellsFemaleImmunotherapyBiological CulturesCellular TypesResearch ArticleAdultDeath RatesImmune CellsImmunologyMalignant Skin NeoplasmsSurgical and Invasive Medical ProceduresDermatologyResearch and Analysis Methods03 medical and health sciencesLymphocytes Tumor-InfiltratingPopulation MetricsHumansDemographyAgedNeoplasm StagingSettore MED/04 - Patologia GeneraleBlood CellsPopulation Biologybusiness.industrylcsh:RCase-control studyBiology and Life SciencesCancers and NeoplasmsCell BiologyCell Culturesmedicine.disease030104 developmental biologyCase-Control StudiesPeople and PlacesImmunologylcsh:QClinical ImmunologyClinical MedicinebusinessPLOS ONE
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VENOUS THROMBOSIS IN FREE FLAPS: A STUDY OF THE PHENOMENOLOGY, HISTORY AND CLINICAL SIGNS IN AN EXPERIMENTAL MODEL OF RATS.

2013

Microsurgeryvenous thrombosiSettore MED/19 - Chirurgia Plasticaflap monitoringfree flap
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DE HOMO RODANS DE REMEDIOS VARO. UN DIALOGO LUDICO Y LUCIDO ENTRE ESCULTURA Y ESCRITURA

2017

EN ESTE ARTICULO SE ANALIZA EL TEXTO NARRATIVO "DE HOMO RODANS" DE LA ARTISTA MEXICANA REMEDIOS VARO, UN TEXTO QUE NACE A RAIZ DE SU ESCULTURA QUE LLEVA EL MISMO NOMBRE.

NARRATIVA LATINOAMERICANA SIGLO XXREMEDIOS VAROSettore L-LIN/06 - Lingua E Letterature Ispano-AmericaneLITERATURA Y ARTES PLASTICAS
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A systematic review of animal models for experimental neuroma

2015

Summary Peripheral neuromas can result in an unbearable neuropathic pain and functional impairment. Their treatment is still challenging, and their optimal management is to be defined. Experimental research still plays a major role, but - although numerous neuroma models have been proposed on different animals - there is still no single model recognised as being the reference. Several models show advantages over the others in specific aspects of neuroma physiopathology, prevention or treatment, making it unlikely that a single model could be of reference. A reproducible and standardised model of peripheral neuroma would allow better comparison of results from different studies. We present a…

Neuroma in continuitymedicine.medical_specialtySettore MED/19 - Chirurgia Plastica610 Medicine & healthPeripheral neuromaTerminal neuromaNeurosurgical ProcedureNeurosurgical ProceduresNeuromaPeripheral Nervous System NeoplasmsEvaluation methodsotorhinolaryngologic diseasesmedicineAnimalsHumans10266 Clinic for Reconstructive SurgeryExperimental neuromaAnimalbusiness.industryMedicine (all)Neoplasms ExperimentalGold standard (test)Nerve injuryNeuromamedicine.diseaseExperimental researchOptimal management2746 SurgerySurgeryAllodyniaGait analysisPeripheral Nervous System NeoplasmSurgerymedicine.symptombusinessNeuroma modelHumanJournal of Plastic, Reconstructive & Aesthetic Surgery
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Criteri di selezione dei pazienti affetti da OSAS da sottoporre a palatofaringoplastica

2009

OSAS Palatofaringoplastica Ipertrofia tonsillare
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Uvulopalatofaringoplastica associata a tonsillectomia nel trattamento dell'OSAS severa

2009

OSAS palatofaringoplastica tonsillectomia
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Sentinel node biopsy for malignant melanoma: a staging procedure only?

2010

Sentinel node biopsy (SNB) is an established staging tool for malignant melanoma. It allows identification of patients with metastatic disease at a very early stage and to collect accurate and complete prognostic information for these patients. Having noted that in a relevant percentage of patients the sentinel node is the only site of metastases, some authors have postulated a therapeutic role for SNB. In this paper, the possibility of a therapeutic role of SNB is evaluated. Relevant literature on the topic has been analyzed. Several findings suggest that not all patients with a positive SNB have further lymph node involvement. The prognostic indicators currently available do not significa…

OncologyBiologic markermedicine.medical_specialtymedicine.diagnostic_testbusiness.industryMelanomaSettore MED/19 - Chirurgia PlasticaDiseaseSentinel nodemedicine.diseasemedicine.anatomical_structureSentinel lymph node biopsy melanoma . Melanoma lymph node metastases . Melanoma prognosis . Prognostic false positivity . Melanoma lymphadenectomyInternal medicineStaging procedureBiopsymedicineSurgeryStage (cooking)businessLymph nodeEuropean Journal of Plastic Surgery
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Prediction of Non-sentinel Node Status in Patients with Melanoma and Positive Sentinel Node Biopsy: An Italian Melanoma Intergroup (IMI) Study

2018

Background and Purpose: Approximately 20% of melanoma patients harbor metastases in non-sentinel nodes (NSNs) after a positive sentinel node biopsy (SNB), and recent evidence questions the therapeutic benefit of completion lymph node dissection (CLND). We built a nomogram for prediction of NSN status in melanoma patients with positive SNB. Methods: Data on anthropometric and clinicopathological features of patients with cutaneous melanoma who underwent CLND after a positive SNB were collected from nine Italian centers. Multivariate logistic regression was utilized to identify predictors of NSN status in a training set, while model efficiency was validated in a validation set. Results: Data …

OncologyMaleSkin NeoplasmsSettore MED/19 - Chirurgia PlasticaLogistic regressionSurgery; Oncology; Sentinel Node Biopsy; Melanoma0302 clinical medicineRisk FactorsMedicine030212 general & internal medicineLymph nodeMelanomaSurgery Oncology lymphnodes melanoma metastasis dissection biomarkerslymphnodesMelanomaTorsoSentinel nodeMiddle AgedTumor Burdenmedicine.anatomical_structuredissectionItalyOncologyHead and Neck Neoplasms030220 oncology & carcinogenesisArea Under CurveLymphatic MetastasisSurgery; OncologyFemalemedicine.medical_specialtyNO03 medical and health sciencesSentinel Node BiopsyInternal medicinemetastasisHumansAgedRetrospective StudiesReceiver operating characteristicbusiness.industrySentinel Lymph Node BiopsybiomarkersExtremitiesNomogrammedicine.diseaseConfidence intervalNomogramsROC CurveCutaneous melanomaLymph Node ExcisionSurgeryLymph Nodesbusiness
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