Search results for "plasticity"
showing 10 items of 765 documents
An Application of Spike-Timing-Dependent Plasticity to Readout Circuit for Liquid State Machine
2007
Liquid state machine (LSM) is a neural system based on spiking neurons that implements a mapping between functions of time. A typical application of LSM is classification of time functions obtained observing the state of the liquid by using a memoryless readout circuit, usually implemented by a linear perceptron. Due to the high number of neurons in the liquid the training of the readout is difficult. In this paper we show that using the Spike-Timing-Dependent Plasticity (STDP) a single neuron with short training session can be used to recognize the state of the liquid due to an input signal. Using STDP it is possible to identify the spikes timing of the neurons in the liquid and this allow…
Recurrence Quantification Analysis as a Methodological Innovation for School Improvement Research
2021
Contains fulltext : 240653.pdf (Publisher’s version ) (Closed access) School improvement and educational change can be facilitated by learning through reflection, as this allows teachers to discover ways to develop and adapt to change. Higher levels of engagement in reflection have been found to be beneficial, but it is unclear from which everyday routine in engagement in reflection higher levels arise, and thus whether occasions to make knowledge explicit should be organized with a certain constancy. In this study, we therefore used a conceptualization of teacher learning through reflection as a situated and dynamic process in which available environmental information, learning activities,…
Isotopic Niche and Trophic Position of the Invasive Portunid Portunus segnis Forskål, (1775) in Elounda Bay (Crete Island, Eastern Mediterranean)
2022
There is a growing recognition that an advanced understanding of the trophic characteristics of an invasive consumer can provide important information on its ecological impact. In recent years, the blue swimming crab Portunus segnis, one of the earliest Lessepsian invaders, has considerably expanded its distribution range in the Mediterranean Sea, yet, its trophic habits in invaded areas remain scarcely investigated. In this study, we used carbon and nitrogen stable isotopes analysis (SIA) to determine the trophic position and isotopic niche of the crab compared with other representatives of the flora and fauna occurring in Elounda Bay (Crete). P. segnis showed a trophic position of 3.9, hi…
Evidence of neuroplasticity in the human visual cortex following beneficial anti-VEGF treatment in exudative age-related macular degeneration
2012
Purpose Anti-vascular endothelial growth factor (VEGF) agents have been shown to improve visual acuity and prevent vision loss in exudative age-related macular degeneration (AMD). As the vision improves relatively quickly in response to intravitreal injections, we wanted to know whether this improvement is reflected in electrophysiolocal markers of visual cortical processing. Methods Our interventional case series included 6 elderly patients who underwent injection treatment to the affected eye. Their visual acuity, tomographic images of retinal thickness and visual evoked potentials (VEP) were assessed before of the treatment and six weeks after the last injection. Results All patients sho…
The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically
2011
Abstract Background Mutations in the gene for Usher syndrome 2A (USH2A) are causative for non-syndromic retinitis pigmentosa and Usher syndrome, a condition that is the most common cause of combined deaf-blindness. To gain insight into the molecular pathology underlying USH2A-associated retinal degeneration, we aimed to identify interacting proteins of USH2A isoform B (USH2AisoB) in the retina. Results We identified the centrosomal and microtubule-associated protein sperm-associated antigen (SPAG)5 in the retina. SPAG5 was also found to interact with another previously described USH2AisoB interaction partner: the centrosomal ninein-like protein NINLisoB. Using In situ hybridization, we foun…
The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity.
2012
The ascending midbrain 5-HT neurons to the forebrain may be dysregulated in depression and have a reduced trophic support. Within situproximity ligation assay (PLA) and supported by coimmunoprecipitation and colocation of the FGFR1 and 5-HT1A immunoreactivities in the midbrain raphe cells, evidence for the existence of FGFR1–5-HT1A receptor heterocomplexes in the dorsal and median raphe nuclei of the Sprague Dawley rat as well as in the rat medullary raphe RN33B cells has been obtained. Especially after combined FGF-2 and 8-OH-DPAT treatment, a marked and significant increase in PLA clusters was found in the RN33B cells. Similar results were reached with the FRET technique in HEK293T cells,…
Active macro-zones algorithm via multidomain SBEM for strain-hardening elastoplastic analysis
2010
In this paper a strategy to perform strain-hardening elastoplastic analysis by using the Symmetric Boundary Element Method (SBEM) for multi-domain type problems is shown. The procedure has been developed inside Karnak.sGbem code by introducing an additional module.
Elastoplastic analysis for active macro-zones via multidomain symmetric Galerkin BEM
2010
In this paper a strategy to perform elastoplastic analysis by using the Symmetric Boundary Element Method (SBEM) for multidomain type problems is shown. This formulation uses a self-stresses equation to evaluate the trial stress in the predictor phase, and to provide the elastoplastic solution in the corrector one. Since the solution is obtained through a return mapping involving simultaneously all the plastically active bem-elements, the proposed strategy does not depend on the path of the plastic strain process and it is characterized by computational advantages due the considerable decrease of the plastic iterations number. This procedure has been developed inside Karnak.sGbem code [1] b…
A Variationally Consistent Time Modelling of Elastic-Plastic Constitutive Equations
1991
A general energy-based time discretization method for evolutive analysis is presented. Most known time integration procedures (mid-point rule, backward difference, etc.) are shown to be particular cases of it. For space continuous systems, a sequence of weighted boundary value problems of deformation-theory plasticity are obtained, each characterizable by a number of variational principles useful for finite element discretization.
Transcranial magnetic stimulation and neuroplasticity
1998
We review past results and present novel data to illustrate different ways in which TMS can be used to study neural plasticity. Procedural learning during the serial reaction time task (SRTT) is used as a model of neural plasticity to illustrate the applications of TMS. These different applications of TMS represent principles of use that we believe are applicable to studies of cognitive neuroscience in general and exemplify the great potential of TMS in the study of brain and behavior. We review the use of TMS for (1) cortical output mapping using focal, single-pulse TMS; (2) identification of the mechanisms underlying neuroplasticity using paired-pulse TMS techniques; (3) enhancement of th…