Search results for "play"
showing 10 items of 706 documents
Internet and computer game addiction - a review of current neuroscientific research
2011
IntroductionA significant part computer game players and internet users show clinical features of abuse and addiction (loss of control, withdrawal symptoms, tolerance, continuation of game play even with increasing negative consequence in social and academic life). Similar mechanisms are suggested to underlie the pathogenesis and maintenance of internet and computer game addiction and substance-related addictions.ObjectivesNeuroscientific research on internet and computer game addiction is sparse, yet emerging. To review previous studies is the objective of the present project.AimsWe aim to identify common findings regarding the neurophysiological processes underlying internet and computer …
Virtualization of Remote Devices and Services in Residential Networks
2009
Lately solutions for remote access for residential services have been proposed. However, these solutions require modifications to the service controllers. In addition, remote access adds complexity to the client application. We propose here a solution for decoupling remote access from the client itself with an entity that creates virtual instances of remote services in a local network. Thereby, clients will be able to discover the virtual instance and use it. Moreover, client applications do not need to distinguish between local and remote services hence reducing complexity.
Three-dimensional ultrasonography in prenatal diagnosis
1995
Within the past five years, 3D ultrasonography has developed to the degree that it offers both the patient and the examiner an entirely new visual experience in prenatal diagnosis. With the system described here (Kretz-technik, Austria), any desired plane can be displayed within the stored volume, and within seconds a high-quality 3D surface or transparent image can be calculated and displayed on the ultrasound monitor without need for an external workstation. All of this can be performed routinely in the clinical setting. Since 1989 we have routinely examined a total of 458 fetuses (242 normal and 216 with anomalies) between 16 and 38 weeks of gestation, supplementing our conventional 2D u…
Sport and Quality of Life
2022
Negli ultimi trent’anni lo sport ha assunto un significato molto rilevante nella vita delle persone e, seppure con notevoli differenze, sia nei paesi a sviluppo economico avanzato, sia in quelli in via di sviluppo. A livello individuale, esso ha costituito un’area di investimento identitario quando ha assunto la forma di sport spettacolo del quale fruire, alimentando la pratica del tifo e il fandom o costituendo il modello di uno stile di vita vincente; ma anche quando ha assunto la forma di pratica del tempo libero attraverso la quale tenersi in forma, facendo crescere, in questo caso, la diffusione di una cultura della salute e del benessere. Si tratta di due modalità di approcciare al co…
Ambient Art : Creative Information Representation
2007
Ambient art is the aesthetic presentation of information, using artistic techniques to achieve a pleasing image that also contains hidden depths, where exposure to it over time allows a viewer to understand something about the information sources that it represents. This paper reviews the artistic and computational background of ambient systems, and presents two case studies of systems developed by our research team, from their initial design to the experiences of the people encountering them. The first case presents a photo mosaic of images based on the news headlines coupled with a structured picture based on the weather; the second presents stylistic perspectives on activity in a public …
Aktivitāšu izstrāde nozares angļu valodas apguvei
2019
Lai saglabātu konkurētspēju savā jomā, profesionāļiem ir jāattīsta jomai atbilstošu angļu valodas zināšanu apguve, bet aizvien pieaugošais pieprasījums pēc nozaru angļu valodas apmācībām rada pieprasījumu arī pēc kompetentiem pasniedzējiem un mācību materiāla izstrādātājiem. Šis darbs tika izstrādāts ar mērķi pētīt nozaru angļu valodas mācību materiālu izveides procesu, kā arī, apmācot studentus, radīt oriģinālu mācību materiālu konkrētai Finanšu menedžmenta programmas studentu grupai. Lai izveidotu šo materiālu, tika iegūti kvalitatīvie dati, analizējot nodarbību laikā novērotos procesus. Jaunizveidotais materiāls tika veiksmīgi izmantots praksē.
Two Overwatch Player Profiles
2022
AbstractWe pursue Overwatch player profiles via a statistical cluster analysis of survey data from the UK (N = 1089) and the USA (N = 417). The profiles are based on the players’ activity, challenge, and experiential preferences as well as motivations. Our analytical process produces six esports player clusters, two of which with Overwatch. The first (OW1) plays mainly Overwatch and Fortnite on a console, and they enjoy diverse types of non-competitive play elements more than other esports players. The second cluster (OW2) plays mainly Overwatch and League of Legends on a PC, and despite appearing more “competitive”, they did not report more competitive preferences. We suggest that the alle…
Type V collagen-induced upregulation of capn2 (large subunit of m-calpain) gene expression and DNA fragmentation in 8701-BC breast cancer cells
2011
Abstract Type V collagen is known to be over-deposited in the stroma of ductal infiltrating carcinomas of the breast. When used as a substrate, type V collagen restrains growth and invasion, and affects gene expression of 8701-BC ductal infiltrating carcinomas cells. Here we supplement existing data by demonstrating type V collagen dependent upregulation of capn2 gene expression in 8701-BC cells through differential display-PCR and Western blot assays. Furthermore, we suggest that our data obtained by centrifugal sedimentation and electrophoresis strongly suggest a correlation between calpain overproduction and DNA fragmentation, since the incubation with calpain inhibitor partly reverts th…
Molecular Design of the Cαβ Interface Favors Specific Pairing of Introduced TCRαβ in Human T Cells
2008
Abstract A promising approach to adoptive transfer therapy of tumors is to reprogram autologous T lymphocytes by TCR gene transfer of defined Ag specificity. An obstacle, however, is the undesired pairing of introduced TCRα- and TCRβ-chains with the endogenous TCR chains. These events vary depending on the individual endogenous TCR and they not only may reduce the levels of cell surface-introduced TCR but also may generate hybrid TCR with unknown Ag specificities. We show that such hybrid heterodimers can be generated even by the pairing of human and mouse TCRα- and TCRβ-chains. To overcome this hurdle, we have identified a pair of amino acid residues in the crystal structure of a TCR that …
In vivophage display: identification of organ-specific peptides using deep sequencing and differential profiling across tissues
2020
ABSTRACTIn vivophage display is widely used for identification of organ- or disease-specific homing peptides. However, the currentin vivophage biopanning approaches fail to assess biodistribution of specific peptide phages across tissues during the screen, thus necessitating laborious and time-consuming post-screening validation studies on individual peptide phages. Here, we adopted bioinformatics tools used for RNA sequencing for analysis of high throughput sequencing (HTS) data to estimate the representation of individual peptides during biopanningin vivo. The data fromin vivophage screen were analyzed using differential binding – relative representation of each peptide in the target orga…