Search results for "plication"

showing 10 items of 8564 documents

AMH MEASUREMENT VERSUS OVARIAN ULTRASOUND IN THE DIAGNOSIS OF POLYCYSTIC OVARY SYNDROME IN DIFFERENT PHENOTYPES.

2015

This study was designed to assess the value of serum anti-Müllerian hormone (AMH) in the diagnosis of polycystic ovary syndrome (PCOS) in various phenotypes and to assess ovarian ultrasound parameters.We performed a retrospective matched controlled study of 113 females with various PCOS phenotypes and 47 matched controls. The diagnostic utility of AMH measurement and ovarian ultrasound were compared. Using receiver operating characteristic (ROC) curve analyses, the threshold for AMH (4.7 ng/mL) and ultrasound parameters (follicle number per ovary [FNPO]22 and ovarian volume [OV]8 cc) were established.In the entire cohort, AMH had a low sensitivity of 79%; while FNPO and OV were 93% and 68%,…

AdultAnti-Mullerian Hormoneendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismOvaryDiagnostic Techniques Endocrine03 medical and health sciencesFollicleYoung Adult0302 clinical medicineEndocrinologymedicineHumansRetrospective StudiesUltrasonographyGynecology030219 obstetrics & reproductive medicineReceiver operating characteristicbiologybusiness.industryUltrasoundOvaryCase-control studyAnti-Müllerian hormoneRetrospective cohort studyGeneral MedicinePolycystic ovaryfemale genital diseases and pregnancy complicationsmedicine.anatomical_structurePhenotypeROC CurveCase-Control Studiesbiology.proteinFemalebusinessPolycystic Ovary SyndromeEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
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Inhibition of tumor cell proliferation in human uterine leiomyomas by vitamin D via Wnt/β-catenin pathway.

2018

To assess the effect of vitamin D (VitD) on human uterine leiomyomas through Wnt/β-catenin pathway inhibition, apoptosis induction, and cell growth arrest.A prospective study comparing leiomyoma vs. myometrium tissues. Paired design study comparing human uterine leiomyoma primary (HULP) cells treated with or without VitD.University hospital.Human uterine leiomyoma and myometrium were collected from women (aged 35-52 years) without hormonal treatment.Samples were collected from women undergoing surgery due to symptomatic uterine leiomyoma pathology.Uterine leiomyoma and myometrium tissues were analyzed by western blot (WB) to determine proliferation, Wnt/β-catenin, and apoptosis pathways. HU…

AdultAntineoplastic AgentsApoptosisTumor Cells CulturedMedicineHumansVitamin DWnt Signaling PathwayCell ProliferationUterine leiomyomaLeiomyomabusiness.industryCell growthWnt signaling pathwayMyometriumObstetrics and GynecologyCell cycleMiddle Agedmusculoskeletal systemmedicine.diseasefemale genital diseases and pregnancy complicationsGene Expression Regulation NeoplasticLeiomyomaReproductive MedicineApoptosisCateninUterine NeoplasmsCancer researchFemalebusinessApoptosis Regulatory ProteinsFertility and sterility
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[Prevalence of pericardial effusion in subjects with rheumatoid arthritis: an echocardiographic study].

1994

We used echocardiography to determine the prevalence of pericardial effusion in rheumatoid arthritis (RA) patients without cardiac systems and compared our results to those obtained in a control group of age-matched subjects. Thirty-six patients with RA (6 men, 30 women; mean age 51 +/- 11 years) were selected from a patient population in treatment at our outpatient Rheumatology Clinic. None of the patients had any symptoms of cardiac disease, and all patients with signs and/or systems of extracardiac disease were excluded from the study. The control group consisted of 60 volunteers (mean age 51 +/- 12 years) randomly selected from a larger group of subjects with neither symptoms, signs and…

AdultArthritis RheumatoidMaleAdult Arthritis Rheumatoid/complications* Cross-Sectional Studies Echocardiography* Female Humans Male Middle Aged Pericardial Effusion/diagnosis Pericardial Effusion/epidemiology* Pericardial Effusion/etiology Time FactorsSettore MED/09 - Medicina InternaCross-Sectional StudiesTime FactorsEchocardiographyHumansFemaleMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolarePericardial EffusionAnnali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna
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Adaptive frequency decomposition of EEG with subsequent expert system analysis.

2001

We present a hybrid system for automatic analysis of clinical routine EEG, comprising a spectral analysis and an expert system. EEG raw data are transformed into the time-frequency domain by the so-called adaptive frequency decomposition. The resulting frequency components are converted into pseudo-linguistic facts via fuzzification. Finally, an expert system applies symbolic rules formulated by the neurologist to evaluate the extracted EEG features. The system detects artefacts, describes alpha rhythm by frequency, amplitude, and stability and after artefact rejection detects pathologic slow activity. All results are displayed as linguistic terms, numerical values and maps of temporal exte…

AdultBiometryAdolescentComputer scienceFuzzy setStability (learning theory)Health InformaticsExpert SystemsElectroencephalographycomputer.software_genreFuzzy logicFuzzy LogicmedicineHumansSensitivity (control systems)Diagnosis Computer-AssistedTheta RhythmAgedAged 80 and overSignal processingBrain Diseasesmedicine.diagnostic_testbusiness.industryPattern recognitionElectroencephalographyMiddle AgedExpert systemComputer Science ApplicationsAlpha RhythmDelta RhythmHybrid systemArtificial intelligencebusinesscomputerAlgorithmComputers in biology and medicine
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Factors associated with epiphora following orbital‐sparing maxillectomy via modified Weber–Ferguson incision with lower blepharoplasty

2021

Purpose The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). Methods We performed a retrospective cohort study enrolling a sample derived from the patient population undergoing OSM-MWFILB over a 7-year period. The predictor variables were grouped into demographic, related health status, anatomic, tumor-specific, and therapeutic categories. The primary outcome variable was the presence of postmaxillectomy epiphora (PME). Descriptive, univariate, and multivariate regression mixed-effect models were computed. Results The …

AdultBlepharoplastyMaleBlepharoplastymedicine.medical_specialtyMultivariate statisticsmedicine.medical_treatment03 medical and health sciences0302 clinical medicineNeoplasmsMaxillamedicineOperating timeHumansIn patientAgedRetrospective StudiesAged 80 and overLacrimal Apparatus DiseasesTumor sizebusiness.industryUnivariateRetrospective cohort studyGeneral MedicineMiddle AgedPrognosisSurgeryOncology030220 oncology & carcinogenesisCarcinoma Squamous CellFemale030211 gastroenterology & hepatologySurgerybusinessComplicationOrbitOrgan Sparing TreatmentsFollow-Up StudiesJournal of Surgical Oncology
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Glucose control in the older patient: from intensive, to effective and safe.

2009

Older adults represent an extensive proportion of Type 2 diabetic patients. Managing diabetes in this population is challenging, because complex comorbidity and disability often mean that guidelines are not suitable on an individual basis. Recent evidence has raised animated discussion of the possibility that intensive glucose control may cause more harm than benefit, especially in older adults. The benefit of glycemic control on microvascular diabetic complications has been consistently demonstrated, but the evidence of benefit on macrovascular disease is not uniform in all studies. Glycemic control appears to prevent the development of cardiovascular events, but is less helpful in seconda…

AdultBlood GlucoseMaleAgingmedicine.medical_specialtyPopulationType 2 diabetesHypoglycemiaDiabetes ComplicationsDiabetes mellitusNeoplasmsmedicineDementiaHumansHypoglycemic AgentsInsulinIntensive care medicineeducationMacrovascular diseaseGlycemicAgedRandomized Controlled Trials as Topiceducation.field_of_studybusiness.industryAge FactorsMiddle Agedmedicine.diseaseComorbidityHypoglycemiaDiabetes Mellitus Type 2Accidental FallsDementiaFemaleGeriatrics and GerontologybusinessAging clinical and experimental research
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Capillary measurement of lactate and glucose for free flap monitoring.

2014

Summary Background It is reported that the salvage rate of free flaps is inversely related to the time interval between the onset of pedicle impairments and their clinical recognition. Monitoring of free flaps is therefore of major importance and clinical monitoring remains the most used technique because of lack of low-cost and non-invasive techniques. The authors suggested an efficient, simple and cheap technique to detect early thrombotic events in monitoring free flaps with skin paddle. Methods In this multicentre prospective study, measurements of capillary glucose and lactate in the flaps were done. These parameters were compared to standardized clinical monitoring during the first fi…

AdultBlood GlucoseMalemedicine.medical_specialtyScreening testFree flapFree Tissue FlapsYoung AdultMedicineHumansLactic AcidProspective StudiesProspective cohort studyAgedMonitoring PhysiologicAged 80 and overbusiness.industryMiddle AgedSkin paddlemedicine.diseaseSurgeryCapillariesVenous thrombosisAnesthesiaSurgeryFemalebusinessComplicationAnnales de chirurgie plastique et esthetique
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Prevalence of diabetes mellitus and impaired glucose tolerance in cystic fibrosis.

1990

The aim of this study was to evaluate the prevalence of impaired glucose tolerance or diabetes mellitus in 99 patients (53 M, 46 F; mean age 10.5 +/- 6.9 years), with cystic fibrosis. Glucose tolerance was evaluated in all patients without overt diabetes using the oral glucose tolerance test (OGTT). Six patients showed a pathological OGTT and 2 patients had insulin-requiring diabetes mellitus. The mean age of the patients with impaired glucose tolerance was significantly higher than that of the subjects with normal glucose metabolism (p less than 0.0001). Patients with overt diabetes mellitus were the oldest subjects in the study group.

AdultBlood GlucoseMalemedicine.medical_specialtyendocrine system diseasesAdolescentCystic FibrosisEndocrinology Diabetes and MetabolismStatistics as TopicCarbohydrate metabolismGastroenterologyCystic fibrosisImpaired glucose toleranceEndocrinologyInternal medicineDiabetes mellitusEpidemiologyInternal MedicinemedicineDiabetes MellitusPrevalenceHumansChildPathologicalGlucose tolerance testmedicine.diagnostic_testbusiness.industrynutritional and metabolic diseasesInfantGeneral MedicineGlucose Tolerance Testmedicine.diseaseEndocrinologyChild PreschoolFemalebusinessComplicationActa diabetologica latina
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Classical cardiovascular risk factors according to fasting plasma glucose levels

2007

To compare the prevalence of classical cardiovascular risk factors (CVRF) and metabolic syndrome (MetS) in our population according to fasting plasma glucose levels (FPG).We have studied 344 subjects between 20-70 years of age, recruited in a Primary Care Clinic. Subjects were divided into four groups according to their fasting plasma glucose (FPG) values: normal plasma glucose (NG) when FPG5.6 mmol/L; FPG between 5.6 and 6.0 mmol/L (FPG1); FPG between 6.1-6.9 mmol/L (FPG2); and diabetes (DM) FPGor = 7 mmol/L or previous diagnosis of diabetes. Cardiovascular risk factors (hypertension, TC/HDL-C index and Apo B values), presence of the MetS and indirect measure of insulin resistance (HOMA) w…

AdultBlood GlucoseMalemedicine.medical_specialtyendocrine system diseasesPopulationCardiovascular risk factorsComorbiditySeverity of Illness IndexRisk FactorsInternal medicinePrevalenceInternal MedicinemedicineHumanseducationPractical implicationsAgedMetabolic Syndromeeducation.field_of_studyPlasma glucosebusiness.industrynutritional and metabolic diseasesType 2 Diabetes MellitusFastingMiddle AgedImpaired fasting glucosemedicine.diseasePrimary care clinicCross-Sectional StudiesEndocrinologyDiabetes Mellitus Type 2Cardiovascular DiseasesSpainFemaleMetabolic syndromebusinessEuropean Journal of Internal Medicine
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Placental infiltration of inflammatory markers in gestational diabetic women.

2013

Gestational diabetes mellitus (GDM) is pathology of glucose intolerance during pregnancy. It is influenced by maternal hyperglycemia and insulinemia through placental circulation. The study was undertaken to investigate the implication of pro-inflammatory factors in the placenta of GDM women. Thirty GDM women have delivered macrosomic babies, and 30 healthy age-matched pregnant women have delivered non macrosomic babies, were recruited in the study. The mRNAs encoding for IL-6, TLR4, TGF-β, CD68, CD14, EMR-1, CCL2, TCR-α, T-bet, GATA-3, leptin and adiponectin were quantified in placental samples by using RT-qPCR. The mRNA expression of the pro-inflammatory factors, i.e., IL-6, TLR4 and TGF-…

AdultBlood Glucosemedicine.medical_specialtyendocrine system diseasesAdolescentPhysiologyPlacentaBiophysicsBiologyYoung AdultPregnancyInternal medicinePlacentaDiabetes mellitusmedicineHumansInsulinRNA Messengerreproductive and urinary physiologyGlycated HemoglobinInflammationPregnancyAdiponectinPlacental CirculationLeptinnutritional and metabolic diseasesGeneral Medicinemedicine.diseasefemale genital diseases and pregnancy complicationsGestational diabetesDiabetes GestationalEndocrinologymedicine.anatomical_structureGene Expression Regulationembryonic structuresGestationFemaleBiomarkersGeneral physiology and biophysics
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