Search results for "points"
showing 10 items of 415 documents
Chromosome 15q BP4-BP5 Deletion in a Girl with Nocturnal Frontal Lobe Epilepsy, Migraine, Circumscribed Hypertrichosis, and Language Impairment
2020
The 15q13.3 microdeletion (microdel15q13.3) syndrome (OMIM 612001) has been reported in healthy subjects as well as in individuals with a wide spectrum of clinical manifestations ranging from mild to severe neurological disorders, including developmental delay/intellectual disability, autism spectrum disorder, schizophrenia, epilepsy, behavioral problems and speech dysfunction. This study explored the link between this genomic rearrangement and nocturnal frontal lobe epilepsy (NFLE), which could improve the clinical interpretation. A clinical and genomic investigation was carried out on an 8-year-girl with a de novo deletion flanking the breakpoints (BPs) 4 and 5 of 15q13.3 detected by arra…
Three solutions for a mixed boundary value problem involving the one-dimensional p-Laplacian
2004
AbstractThis paper deals with two mixed nonlinear boundary value problems depending on a parameter λ. For each of them we prove the existence of at least three generalized solutions when λ lies in an exactly determined open interval. Usefulness of this information on the interval is then emphasized by means of some consequences. Our main tool is a very recent three critical points theorem stated in [Topol. Methods Nonlinear Anal. 22 (2003) 93–104].
On a mixed boundary value problem involving the p-Laplacian
2011
In this paper we prove the existence of infinitely many solutions for a mixed boundary value problem involving the one dimensional p-Laplacian. A result on the existence of three solutions is also established. The approach is based on multiple critical points theorems.
A Mixed Methods Study to Examine the Influence of CLIL on Physical Education Lessons: Analysis of Social Interactions and Physical Activity Levels
2020
Physical Education is often selected for applying multilingual initiatives through the use of a content and language integrated learning (CLIL) approach. However, it is still unclear whether the introduction of such an approach might entail losing the essence of physical education and distorting its basic purposes. The aim of this study is to analyze the impact of CLIL on physical education lessons. Given the purpose of this study, a mixed methodological approach based on a sequential exploratory design divided into two different phases is used. We begin with initial qualitative data collection (phase I), consisting of the analysis of interviews with 12 participants (8 teachers and 4 studen…
Geometric quality and appearance of surfaces : local and global approaches
2012
Accounting for customers' perception of manufactured goods has become a major challenge for the industry. This process is to be established from early design to retail. Customers are nowadays more aware and detail oriented about perceived quality of products. This allows one to set not only an estimated price but also the expected quality of the product. Surface appearance analysis has therefore become a key industrial issue. Two approaches are proposed here to formalize the detection methodology and provide objective criteria for experts to evaluate surface anomalies. The first proposed approach is based on surface metrology. It consists in analyzing the measured topologies in order to bin…
Chimeric Genomes of Natural Hybrids of Saccharomyces cerevisiae and Saccharomyces kudriavzevii
2009
11 pages, 6 figures.-- PMID: 19251887 [PubMed].-- Printed version published Apr 2009.
FISH mapping of the sex-reversal region on human chromosome 9p in two XY females and in primates
2000
Accumulating evidence suggests that haploinsufficiency of a dosage-sensitive gene(s) in human chromosome 9p24.3 is responsible for the failure of testicular development and feminisation in XY patients with monosomy for 9p. We have used molecular cytogenetic methods to characterise the sex-reversing 9p deletions in two XY females. Fluorescence in situ hybridisation (FISH) with YACs from the critical 9p region containing an evolutionarily conserved sex-determining gene, DMRT1, is a very fast and reliable assay for patient screening. Comparative YAC mapping on great ape and Old and New World monkey chromosomes demonstrated that the critical region was moved from an interstitial position on the…
Ser uno mismo. Repensando la autonomía y la responsabilidad como coordenadas de la educación actual
2012
One of the main goals of education in the 21st Century is developing students’ autonomy and responsibility. The first is to guarantee the shaping of each individual’s identity, which at the same time entails a pledge to one’s self, to others and to the surrounding reality. The second is in response to our ability to make commitments. To this end we must first immerse ourselves in the concepts of individuality and freedom, which are at the heart of the subject’s awakening and the development of his or her identity. Second, we must outline to all people their rights and duties which will act as permanent reference points that are valid for any situation of interaction. This will finally allow…
Fair Executive Compensation: Is Kalai-Smorodinsky More Just than Nash ?
2015
By considering Phelps' curve, the best disagreement point (BATNA) and the gains of negotiation, we examine what a fair distribution of executive wages should be. Beyond equality and Rawls' maximin, we focus on equality-of-gains (Nash) and on relative-equality-of-gains (Kalai-Smorodinsky). Equality-of-gains is close to maximin; executives may not accept to bargain. Relative-equality-of-gains allows executives and workers to obtain equal gains in percentage; executive compensation is not intolerably high to the price of a higher total payroll.
Remark on a nonlocal isoperimetric problem
2017
Abstract We consider isoperimetric problem with a nonlocal repulsive term given by the Newtonian potential. We prove that regular critical sets of the functional are analytic. This optimal regularity holds also for critical sets of the Ohta–Kawasaki functional. We also prove that when the strength of the nonlocal part is small the ball is the only possible stable critical set.