Search results for "ponti"

Silica as a morphogenetically active inorganic polymer.

2013

At present the scaffolds used for bioprinting of cells do not elicit morphogenetic responses in the cells. In the present study we approached a solution by studying the effect of an inorganic silica supplement added to an Na-alginate matrix. Bone- and osteoblast-like SaOS-2 cells were embedded into this organic polymeric matrix which was additionally enriched with 400 μM prehydrolyzed TEOS [tetra-ethoxy-silane], a source of ortho-silicate. In this silica-based matrix the cells synthesized hydroxyapatite crystallites after exposure to a mineralization activation cocktail composed of β-glycerophosphate, ascorbic acid and dexamethasone. The degree of hydroxyapatite synthesis, determined by sta…

Pragmatica, que su Magestad ha mandado publicar, para que de oy en adelante no se dè curso à Breve, Bulla, Rescripto, ò Carta Pontificia, que esta…

1762

Escut reial xil. a la port. Caplletra ornada ; Fris Sign.: [ ]1, A4 Reclams

Keratinocytes Determine Th1 Immunity during Early Experimental Leishmaniasis

2010

Experimental leishmaniasis is an excellent model system for analyzing Th1/Th2 differentiation. Resistance to Leishmania (L.) major depends on the development of a L. major specific Th1 response, while Th2 differentiation results in susceptibility. There is growing evidence that the microenvironment of the early affected tissue delivers the initial triggers for Th-cell differentiation. To analyze this we studied differential gene expression in infected skin of resistant and susceptible mice 16h after parasite inoculation. Employing microarray technology, bioinformatics, laser-microdissection and in-situ-hybridization we found that the epidermis was the major source of immunomodulatory mediat…

Urbanus P.P. VIII. Ad perpetuam rei memoriam ... Sanè delectus filius Dydacus de Sancto Raymūdo Procurator Generalis Ordinis Fratrum Discalceatorum…

1625

Tres escuts grav. en la parte superior del f.

Por el derecho de la Corona, en el aumento de los Diezmos, y en los Novales del Arzobispado de Valencia. Contra el M. R. Arzobispo, su Cabildo, difer…

1762

Precedeix al tít.: "J. M. J." Inclou Butlles de Gregori VII i Urbà II i Carta d'Alfons V d'Aragó Caplletres ornades Sign.: [A]2, B-Ii2, a-d2 Text amb postil·les i notes marginals i envoltant el text Reclams Les Butlles i la Carta a dues col. separades per banda, les butlles bilingües: llatí i castellà

Gio Ponti dalla scena al grattacielo. Un unico modo

2012

Bitecten. Beatificationis, et Canonizationes servi Dei Iacobi Illyrici, vulgò de Bitecto nuncupati, Laici Ordinis Minorum Observantium Sancti Franci…

1701

Tít. al marge lateral del text sobre Giacomo da Bitetto: Decretum S. Cong. Rituum cum approbatione ... Clementis XI super Cultu immemorabili B. Iacobi Illyrici Minor. Observ. S. Francisci Com a tít. del Breu (a la part inferior del f.), el que va al marge lateral Inclou: Breve ... Clementis XI Pro Indulge[n]tia plenaria perpetua in Ecclesijs Fratrum, & Monialium Ministro Generali Ordinis Minorum de Observa[n]tia subiectis, tàm erectis, quàm erigendis in toto Orbe. Pro Festo S. Rosae Virginis Viterbiensis eiusdem Ordinis die 4. Septembris [Dat. Romae ... die 14. Ianuarij 1701 Caplletres ornades

Nature and origin of natural Zn clay minerals from the Bou Arhous Zn ore deposit: Evidence from electron microscopy (SEM-TEM) and stable isotope comp…

2016

International audience; Zn-clay minerals have been found in the non-sulfide deposit of Bou Arhous (High Atlas, Morocco). They occur as white or ochre clays embedding willemite (Zn2SiO4) and are commonly associated to red detrital clays in karstic cavities. Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD) and Transmission Electron Microscopy (TEM) with Energy Dispersive X-ray (EDX) analyses were combined in order to characterize the clay minerals and to determine the mechanism of their formation. XRD patterns on oriented and powdered clays and Fourier Transform Infrared (FTIR) spectroscopic analyses suggest that fraipontite is the major Zn clay phase (with some smectite interstrat…

Influence of different approaches to the cerebellopontine angle on the function of the intermediate nerve

2007

Object Surgery in the cerebellopontine angle (CPA) is a standard procedure at many centers. Outcome is focused mainly on preservation of hearing and facial function postoperatively. The nonmotor part of the facial nerve, the intermediate nerve, is nearly neglected nowadays. Methods A retrospective study was designed, including a questionnaire that was sent to 178 patients who had undergone surgery between 2000 and 2004. Data were obtained in 156 cases. The questionnaire was divided into five parts assessing the presence of increased tearing, reduced tearing, salivation disturbances, increased nasal secretions, and abnormalities in taste. Finally, a self-assessment of patient symptoms was a…

Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells

2004

AbstractThis study describes the molecular mechanism by which treatment with 3-AB, a potent inhibitor of PARP, allows human osteosarcoma MG-63 cells to restrict growth and enter differentiation. Our findings show that in MG-63 cells, aberrant gene expression keeps Rb protein constitutively inactivated through hyperphosphorylation and this promotes uncontrolled proliferation of the cells. After 3-AB-treatment, the poly(ADP-ribosyl)ation of nuclear proteins markedly decreases and this results in an increase in both the hypophosphorylated active form of Rb and pRb/E2F complexes. These effects are accompanied by G1 arrest, downregulation of gene products required for proliferation (cyclin D1, β…