Search results for "porous material"

showing 10 items of 361 documents

Finely Tuned Temperature-Controlled Cargo Release Using Paraffin-Capped Mesoporous Silica Nanoparticles

2011

[EN] Trapped: Mesoporous silica nanoparticles were loaded with a fluorescent guest and functionalized with octadecyltrimethoxysilane. The alkyl chains interact with paraffins, which build a hydrophobic layer around the particle (see picture). Upon melting of the paraffin, the guest molecule is released, as demonstrated in cells for the guest doxorubicin. The release temperature can be tuned by choosing an appropriate paraffin. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Models MolecularINGENIERIA DE LA CONSTRUCCIONGuest moleculesParaffinsParaffin waxesNanoparticlemesoporous materialsMCM-41Phenazine derivativeFunctionalizedCell survivalNanoparticleQUIMICA ORGANICAChemical structureX-Ray DiffractionSafranin tSilicon dioxideControlled releaseAlkyl chainDrug CarriersMicroscopy ConfocalMolecular StructureOctadecyltrimethoxysilaneSurface propertyTemperatureSilicaGeneral MedicineChemistryAntineoplastic agentParaffinHeLa cellPorosityHumanMaterials scienceDrug carrierX ray diffractionSurface PropertiesMesoporous silica nanoparticlesNanotechnologyAntineoplastic AgentsMesoporousCatalysisDrug interactionsArticleMicroscopy Electron TransmissionHumansCell survivalDrug effectDelayed release formulationHydrophobic layersQUIMICA INORGANICAGeneral ChemistryMesoporous silicaMolecular gatesMesoporous materialsMcm 41Confocal microscopyDrug effectSolubilityDoxorubicinDelayed-Action Preparationsdrug deliveryDrug deliveryNanoparticlesPhenazinesnanoparticlesMesoporous materialcontrolled releasemolecular gatesTransmission electron microscopyHeLa CellsAngewandte Chemie
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Ion transport and selectivity in nanopores with spatially inhomogeneous fixed charge distributions

2007

Polymeric nanopores with fixed charges show ionic selectivity when immersed in aqueous electrolyte solutions. The understanding of the electrical interaction between these charges and the mobile ions confined in the inside nanopore solution is the key issue in the design of potential applications. The authors have theoretically described the effects that spatially inhomogeneous fixed charge distributions exert on the ionic transport and selectivity properties of the nanopore. A comprehensive set of one-dimensional distributions including the skin, core, cluster, and asymmetric cases are analyzed on the basis of the Nernst-Planck equations. Current-voltage curves, nanopore potentials, and tr…

Models MolecularMaterials scienceStatic ElectricityGeneral Physics and AstronomyIonic bondingNanotechnologyElectrolyteIon ChannelsNanoporous materialsIonQuantitative Biology::Subcellular ProcessesElectrolytesBiopolymersIonic conductivityStatic electricityCluster (physics)Ionic conductivityComputer SimulationPhysical and Theoretical Chemistry:FÍSICA::Química física [UNESCO]AnisotropyIon TransportUNESCO::FÍSICA::Química físicaNanostructuresNanoporeModels ChemicalPolymer solutionsChemical physicsNanoporous materials ; Polymer solutions ; Electrolytes ; Ionic conductivityAnisotropyIon Channel GatingPorosityThe Journal of Chemical Physics
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Identification of New Templates for the Synthesis of BEA, BEC, and ISV Zeolites Using Molecular Topology and Monte Carlo Techniques

2020

The presence of organic structure directing agents (templates) in the synthesis of zeolites allows the synthesis to be directed, in many cases, toward structures in which there is a large stabilization between the template and the zeolite micropore due to dispersion interactions. Although other factors are also important (temperature, pH, Si/Al ratio, etc.), systems with strong zeolite-template interactions are good candidates for an application of new computational algorithms, for instance those based in molecular topology (MT), that can be used in combination with large databases of organic molecules. Computational design of new templates allows the synthesis of existing and new zeolites …

Models MolecularQuantitative structure–activity relationshipMaterials science010304 chemical physicsGeneral Chemical EngineeringMonte Carlo methodGeneral ChemistryMicroporous materialLibrary and Information Sciences01 natural sciences0104 chemical sciencesComputer Science Applications010404 medicinal & biomolecular chemistryIdentification (information)Template0103 physical sciencesZeolitesMoleculeMinificationMolecular topologyBiological systemMonte Carlo MethodJournal of Chemical Information and Modeling
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Magnesium Exchanged Zirconium Metal−Organic Frameworks with Improved Detoxification Properties of Nerve Agents

2019

UiO-66, MOF-808 and NU-1000 metal-organic frameworks exhibit a differentiated reactivity toward [Mg(OMe)2(MeOH)2]4 related to their pore accessibility. Microporous UiO-66 remains unchanged while mesoporous MOF-808 and hierarchical micro/mesoporous NU-1000 materials yield doped systems containing exposed MgZr5O2(OH)6 clusters in the mesoporous cavities. This modification is responsible for a remarkable enhancement of the catalytic activity toward the hydrolytic degradation of P-F and P-S bonds of toxic nerve agents, at room temperature, in unbuffered aqueous solutions.

Models MolecularSurface PropertiesQuímica organometàl·licachemistry.chemical_element010402 general chemistry01 natural sciencesBiochemistryCatalysisCatalysisColloid and Surface ChemistryPolymer chemistryReactivity (chemistry)MagnesiumParticle SizeMaterialsMetal-Organic FrameworksZirconiumAqueous solutionMagnesiumHydrolysisTemperatureGeneral ChemistryMicroporous material0104 chemical scienceschemistryMetal-organic frameworkZirconiumMesoporous materialNerve AgentsOxidation-ReductionPorosity
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Delivery modulation in silica mesoporous supports via alkyl chain pore outlet decoration

2012

This article focuses on the study of the release rate in a family of modified silica mesoporous supports. A collection of solids containing ethyl, butyl, hexyl, octyl, decyl, octadecyl, docosyl, and triacontyl groups anchored on the pore outlets of mesoporous MCM-41 has been prepared and characterized. Controlled release from pore voids has been studied through the delivery of the dye complex tris(2,2¿-bipyridyl)ruthenium(II). Delivery rates were found to be dependent on the alkyl chain length anchored on the pore outlets of the mesoporous scaffolding. Moreover, release rates follow a Higuchi diffusion model, and Higuchi constants for the different hybrid solids have been calculated. A decr…

Models MolecularTrisINGENIERIA DE LA CONSTRUCCIONSurface Propertieschemistry.chemical_elementMolecular Dynamics SimulationMolecular dynamicschemistry.chemical_compoundQUIMICA ORGANICAOrganometallic CompoundsElectrochemistryOrganic chemistryGeneral Materials ScienceParticle SizePorositySpectroscopyAlkylchemistry.chemical_classificationQUIMICA INORGANICASurfaces and InterfacesSilicon DioxideCondensed Matter PhysicsControlled releaseRutheniumChemical engineeringchemistryParticle sizeMesoporous materialPorosity
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Controlling the molecular diffusion in MOFs with the acidity of monocarboxylate modulators.

2021

The catalytic performance of metal-organic frameworks (MOFs) is related to their physicochemical properties, such as particle size, defect-chemistry and porosity, which synthetic control can be potentially achieved by coordination modulation. By combining PXRD, 1HNMR, FT-IR, N2 uptake measurements we have found insights that the different types of defects (missing linker or missing clusters consequence of the spatial distribution of missing linkers, and the combination of both) could be controlled by the type of modulator employed. We show that the molar percent of defects, either as missing linkers or as part of missing cluster defects, is related to the modulator’s acidity and subse…

Molecular diffusionMetal-Organic Frameworks Defects Coordination modulation Heterogeneous Catalysis010405 organic chemistryChemistry010402 general chemistry01 natural sciences0104 chemical sciencesCatalysisInorganic ChemistryChemical engineeringCluster (physics)Particle sizePorosityMesoporous materialLinkerPowder diffractionDalton transactions (Cambridge, England : 2003)
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ChemInform Abstract: Hybrid Materials Based on Magnetic Layered Double Hydroxides: A Molecular Perspective

2015

ConspectusDesign of functional hybrids lies at the very core of synthetic chemistry as it has enabled the development of an unlimited number of solids displaying unprecedented or even improved properties built upon the association at the molecular level of quite disparate components by chemical design. Multifunctional hybrids are a particularly appealing case among hybrid organic/inorganic materials. Here, chemical knowledge is used to deploy molecular components bearing different functionalities within a single solid so that these properties can coexist or event interact leading to unprecedented phenomena. From a molecular perspective, this can be done either by controlled assembly of orga…

Molecular levelChemistryIntercalation (chemistry)Layered double hydroxidesengineeringInorganic materialsNanotechnologyGeneral Medicineengineering.materialHybrid materialMesoporous materialChemical designChemInform
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Flow-through pore characteristics of monolithic silicas and their impact on column performance in high-performance liquid chromatography

2008

Abstract In order to elucidate the role of the flow-through characteristics with regard to the column performance in high-performance liquid chromatography (HPLC) native and n -octadecyl bonded monolithic silica rods and columns, respectively of 100 mm length and 4.6 mm ID with mesopores in the range between 10 and 25 nm and macropores in the range between 0.7 and 6.0 μm were examined by mercury intrusion/extrusion, scanning electron microscopy, image analysis and permeability. The obtained data of the flow-through pore sizes and porosity values as well as surface-to-volume ratio of the stationary phase skeleton enabled to predict their influence to the chromatographic separation efficiency…

Monolithic HPLC columnChromatographyChemistryScanning electron microscopeSilica gelOrganic ChemistryAnalytical chemistryGeneral MedicinePorosimetryReversed-phase chromatographySilicon DioxideBiochemistryAnalytical ChemistrySeparation processchemistry.chemical_compoundMicroscopy Electron ScanningPorosityMesoporous materialPorosityChromatography High Pressure LiquidJournal of Chromatography A
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Comprehensive pore structure characterization of silica monoliths with controlled mesopore size and macropore size by nitrogen sorption, mercury poro…

2005

The porosity of monolithic silica columns is measured by using different analytical methods. Two sets of monoliths were prepared with a given mesopore diameter of 10 and 25 nm, respectively and with gradated macropore diameters between 1.8 and 7.5 microm. After preparing the two sets of monolithic silica columns with different macro- and mesopores the internal, external and total porosity of these columns are determined by inverse size-exclusion chromatography (ISEC) using polystyrene samples of narrow molecular size distribution and known average molecular weight. The ISEC data from the 4.6 mm analytical monolithic silica columns are used to determine the structural properties of monolithi…

Monolithic HPLC columnChromatographyMacroporeScanning electron microscopeChemistryOrganic ChemistrySize-exclusion chromatographyAnalytical chemistrySilica GelMercuryGeneral MedicinePorosimetrySilicon DioxideBiochemistryAnalytical ChemistryAdsorptionMicroscopy Electron TransmissionChromatography GelMicroscopy Electron ScanningAdsorptionMesoporous materialPorosityGelsPorosityJournal of Chromatography A
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Textural characterization of native and n-alky-bonded silica monoliths by mercury intrusion/extrusion, inverse size exclusion chromatography and nitr…

2008

Native and n-alkyl-bonded (n-octadecyl) monolithic silica rods with mesopores in the range between 10 and 25 nm and macropores in the range between 1.8 and 6.0 microm were examined by mercury intrusion/extrusion, inverse size exclusion chromatography (ISEC) and nitrogen sorption. Our results reveal very good agreement for the mesopore size distribution obtained from nitrogen adsorption (in combination with an advanced NLDFT analysis) and ISEC. Our studies highlight the importance of mercury porosimetry for the assessment of the macropore size distribution and show that mercury porosimetry is the only method which allows obtaining a combined and comprehensive structural characterization of m…

Monolithic HPLC columnChromatographyNitrogenOrganic ChemistryAnalytical chemistrychemistry.chemical_elementSorptionMercuryGeneral MedicinePorosimetryMesoporous silicaSilicon DioxideBiochemistryAnalytical ChemistryMercury (element)AdsorptionchemistryChromatography GelExtrusionAdsorptionMesoporous materialPorosityJournal of Chromatography A
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