Search results for "porte"
showing 10 items of 1894 documents
Gestión de proyectos: antecedentes y consecuentes en el contexto del proyecto y de la organización
2020
En los entornos actuales, caracterizados por altos niveles de competitividad e incertidumbre, las organizaciones se han enfocado en desarrollar sus actividades a través de proyectos, orientados al logro de los objetivos estratégicos. La gestión de proyectos [Project Management (PM)], se refiere a la aplicación de conocimientos, habilidades, herramientas, técnicas, métodos y competencias, a las actividades de los proyectos, con el objetivo alcanzar el éxito en el desempeño de los mismos. En este sentido, la PM, ha adquirido una alta relevancia, por el impacto que genera en la competitividad de las empresas y en el desarrollo económico de los países. A nivel científico, se han logrado avances…
Efectos fisiológicos y psicológicos de un nuevo deporte de raqueta en niños con y sin sobrepeso en la escuela primaria
2020
Este artículo se encuentra disponible en la siguiente URL: https://ccd.ucam.edu/index.php/revista/article/view/1514/503 En este artículo también participan: Jorge Flández, Michael E. Rogers y Juan C. Colado.
Mejora humana y dopaje en la actual filosofía del deporte
2014
Esta tesis parte del hecho de que resulta esencial realizar una reflexión crítica sobre el deporte. Éste no sólo ejemplifica algunas de las características y capacidades que consideramos como más propiamente humanas, sino que los seres humanos que nos vemos relacionados con el deporte nos hacemos a través de él. Esto ha sido una constante a lo largo de la Historia. No hay más que ver que todas las civilizaciones anteriores a la nuestra han tenido una actividad deportiva que ha resultado central para comprender el funcionamiento de su sociedad. Una práctica deportiva más crítica y mejor, conduciría a una sociedad mejor. Principalmente, porque la tarea ética de lograr un mundo más ético no la…
Screening for Solute Transporters in Plant Photosynthetic Membranes
2008
As compared to chloroplast envelope transporters, the field of thylakoid transporters is largely unexplored. There is evidence for several transport activities in the plant thylakoid membrane, but only a copper P-type ATPase and an ATP/ADP carrier have been so far identified at the gene level in Arabidopsis thaliana. Using in silico analyses, we have predicted the existence of approximately 15 thylakoid transporters, including phosphate transporters and cation channels. For experimental validation, we have used peptide- specific antibodies and functional analyses in heterologous system. These novel data are highly relevant to understand the transport network of the thylakoid membrane and it…
Association between use of novel glucose-lowering drugs and COVID-19 hospitalization and death in patients with type 2 diabetes: a nationwide registr…
2022
Abstract Aims Type 2 diabetes (T2DM) in patients with coronavirus disease-19 (COVID-19) is associated with a worse prognosis. We separately investigated the associations between the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1 RA), and dipeptidyl peptidase-4 inhibitors (DPP-4i), and the risk of COVID-19 hospitalization and death. Methods and results Patients with T2DM registered in the Swedish National Patient Registry and alive on 1 February 2020 were included. ‘Incident severe COVID-19’ was defined as the first hospitalization and/or death from COVID-19. A modified Poisson regression approach was applied to a 1:1 propensity sc…
The effects of nitric oxide on striatal serotoninergic transmission involve multiple targets: an in vivo microdialysis study in the awake rat
2004
Abstract The role of endogenous nitric oxide (NO) in N -methyl- d -aspartate (NMDA)-induced modulation of serotonin (5-HT) release in the striatum of freely moving rats has been studied using microdialysis technique. NMDA-induced increase in 5-HT release was significantly inhibited by selective nitric oxide synthase (nNOS) inhibitor S -methylthiocitrulline (S-Me-TC), ONOO − scavenger l -cysteine ( l -cys), and guanylate cyclase (GC) inhibitor 1 H [1,2,4]oxadiazolo[4,3- a ]quinoxalin-1-one (ODQ). These data suggest that modulation of 5-HT levels is linked to the formation of NO produced by NMDA receptor activation and that endogenously produced NO increases 5-HT concentrations both by stimul…
Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor
2020
The intensive use of pesticides has led to their increasing presence in water, soil, and agricultural products. Mounting evidence indicates that some pesticides may be endocrine disrupting chemicals (EDCs), being therefore harmful for the human health and the environment. In this study, three pesticides, glyphosate, thiacloprid, and imidacloprid, were tested for their ability to interfere with estrogen biosynthesis and/or signaling, to evaluate their potential action as EDCs. Among the tested compounds, only glyphosate inhibited aromatase activity (up to 30%) via a non-competitive inhibition or a mixed inhibition mechanism depending on the concentration applied. Then, the ability of the thr…
Health-Related Quality of Life Issues Experienced by Thoracic and Breast Sarcoma Patients: A Rare and Understudied Group
2021
Thoracic and breast sarcomas constitute a rare subgroup within the sarcoma population. There is limited knowledge about their health-related quality of life (HRQoL) and a valid disease-specific HRQoL instrument is lacking. This qualitative study aimed to investigate the HRQoL issues experienced by a small group of thoracic and breast sarcoma patients. Semi-structured interviews with 19 thoracic and four breast sarcoma patients were conducted and thematically analysed. Physical issues mentioned by both groups were fatigue, sleep disturbances, pain, wound infections, and symptoms related to chemotherapy and radiotherapy. Tightness in the back and restrictions in performing tasks above arm hei…
L’influence de la volonté de contrôler la transaction sur la nature du processus de sélection d’un circuit de revente
2017
International audience; Afin de considérer le rôle actif du consommateur lors de la revente de ses biens, cette recherche se propose de compléter les travaux existants sur le choix d'un circuit de distribution en intégrant la notion de contrôle. Nous souhaitons aussi élargir la vision analytique des travaux consacrés à la sélection d’un circuit de distribution par l’analyse de la nature du processus décisionnel de l’individu en fonction de sa volonté de contrôler la transaction. Les résultats de notre expérimentation menée auprès de 152 individus mettent en avant que certaines dimensions de la volonté de contrôler la transaction influencent la nature du processus de décision de l’individu. …
L'affectif dans les comportements d'achat et de consommation
2010
National audience; ...