Search results for "position"
showing 10 items of 6771 documents
Modeling of 137Cs migration in soils using an 80-year soil archive: role of fertilizers and agricultural amendments
2008
An 80-year soil archive, the 42-plot experimental design at the INRA in Versailles (France), is used here to study long-term contamination by 137Cs atmospheric deposition and the fate of this radioisotope when associated with various agricultural practices: fallow land, KCl, NH4(NO3), superphosphate fertilizers, horse manure and lime amendments. The pertinence of a simple box model, where radiocaesium is supposed to move downward by convectional mechanisms, is checked using samples from control plots which had been neither amended, nor cultivated since 1928. This simple model presents the advantage of depending on only two parameters: α, a proportional factor allowing the historical atmosph…
Electoral Debates. The Last Stronghold Against Mediatization? A Case Study of the 2015 Spanish General Elections
2018
26 Páginas La mediatización de la política alcanza su máxima expresión con motivo de las campañas electorales, en las que los actores políticos se afanan por lanzar sus mensajes persuasivos al espacio público, con el fin de acceder y, en última instancia, convencer al electorado. Este artículo se propone analizar el discurso político en los debates electorales televisados durante la campaña de las elecciones generales españolas de diciembre de 2015. El objetivo del análisis es observar qué temas destacaron en las intervenciones de los actores políticos y determinar si la mediatización afecta el contenido de los debates electorales, o si, por el contrario, estos espacios se mantienen como fo…
Oligarchies and Client Systems in Rural communities in the South of the Crown of Aragón (13th to 15th Centuries)
2010
Studies of late medieval Hispanic client systems generally focus on networks of noble power, to the exclusion of the peasantry. This is doubtless in part because the peasantry has traditionally been considered to represent a largely homogenous social group defined in opposition to the feudal nobility, whose members defended common interests. However, the last few years have witnessed a profusion of studies into the rural, or peasant, elites of Western Europe during the late medieval and modern periods, and these highlight not only significant disparities between the economic status of those and that of the remainder of the peasantry, but also their employment of specific power-mechanisms in…
No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Data…
2021
Background. Lynch syndrome is the most common genetic predisposition for hereditary cancer. Carriers of pathogenic changes in mismatch repair (MMR) genes have an increased risk of developing colorectal (CRC), endometrial, ovarian, urinary tract, prostate, and other cancers, depending on which gene is malfunctioning. In Lynch syndrome, differences in cancer incidence (penetrance) according to the gene involved have led to the stratification of cancer surveillance. By contrast, any differences in penetrance determined by the type of pathogenic variant remain unknown. Objective. To determine cumulative incidences of cancer in carriers of truncating and missense or aberrant splicing pathogenic …
Sepsis in head and neck cancer patients treated with chemotherapy and radiation: literature review and consensus
2015
Abstract: The reporting of infection/sepsis in chemo/radiation-treated head and neck cancer patients is sparse and the problem is underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met with the aim of reaching a consensus on a clinical definition and management of infections and sepsis. The Delphi appropriateness method was used for this consensus. External expert reviewers then evaluated the conclusions carefully according to their area of expertise. The paper contains seven clusters of statements about the clinical definition and management of infections and sepsis in head and neck cancer patients, which had a consensus. Furthermore, it offers a revie…
Genetic and Molecular Characterization of The Human Osteosarcoma 3AB-OS Cancer Stem Cell Line: A Possible Model For Studying Osteosarcoma Origin and …
2013
Finding new treatments targeting cancer stem cells (CSCs) within a tumor seems to be critical to halt cancer and improve patient survival. Osteosarcoma is an aggressive tumor affecting adolescents, for which there is no second-line chemotherapy. Uncovering new molecular mechanisms underlying the development of osteosarcoma and origin of CSCs is crucial to identify new possible therapeutic strategies. Here, we aimed to characterize genetically and molecularly the human osteosarcoma 3AB-OS CSC line, previously selected from MG63 cells and which proved to have both in vitro and in vivo features of CSCs. Classic cytogenetic studies demonstrated that 3AB-OS cells have hypertriploid karyotype wit…
Generalization of Linked Canonical Polyadic Tensor Decomposition for Group Analysis
2019
Real-world data are often linked with each other since they share some common characteristics. The mutual linking can be seen as a core driving force of group analysis. This study proposes a generalized linked canonical polyadic tensor decomposition (GLCPTD) model that is well suited to exploiting the linking nature in multi-block tensor analysis. To address GLCPTD model, an efficient algorithm based on hierarchical alternating least squa res (HALS) method is proposed, termed as GLCPTD-HALS algorithm. The proposed algorithm enables the simultaneous extraction of common components, individual components and core tensors from tensor blocks. Simulation experiments of synthetic EEG data analysi…
Carbohydrates as Chemical Constituents of Biowaste Composts and their Humic and Fulvic Acids
1995
The decomposition of organic matter of source-separated biowaste during composting was followed during 18 months. Compost samples were fractionated into three parts: (i) hot water soluble extract (HWE) (ii) bitumen fraction and (iii) humic substances (humic acids (HA) and fulvic acids (FA)). Original compost samples and the HA and FA fractions were hydrolyzed with sulfuric acid for hexoses and pentoses. Quantitative spectrophotometric and qualitative GC/MS analyses of monosaccharides as trimethylsilyl ethers of the corresponding alditols were carried out.During composting, the amount of HA in the organic matter of the compost increased, the amounts of HWE and bitumen decreased and the amoun…
Accelerometer-Based Sedentary Time, Physical Activity, and Serum Metabolome in Young Men
2022
Physical activity (PA) has been shown to associate with many health benefits but studies with metabolome-wide associations with PA are still lacking. Metabolome studies may deepen the mechanistic understanding of PA on the metabolic pathways related to health outcomes. The aim of the present study was to study the association of accelerometer based sedentary time (SB) and PA with metabolome measures. SB and PA were measured by a hip-worn accelerometer in 314 young adult men (age: mean 28, standard deviation 7 years). Metabolome was analyzed from fasting serum samples consisting of 66 metabolome measures (nuclear magnetic resonance-based metabolomics). The associations were analyzed using a …
Role of genetic polymorphisms in myocardial infarction at young age
2010
Acute myocardial infarction (AMI) in young adult presents a typical pattern of risk factors, clinical, angiographic and prognostic characteristics. In the last years we demonstrated that hemorheological profile is altered in these patients in a persistent way and independently of the number of risk factors and of the extent of coronary lesions. Thus, the hyperviscosity syndrome following AMI could be considered an intrinsic characteristic of these patients. Consequently it is possible to hypothesise the presence of a genetic background at the origin of this predisposition. If this background is able to influence the risk of ischemic heart disease, this should be particularly evident in youn…