Search results for "position"
showing 10 items of 6771 documents
On the synthesis of functionalized porphyrins and porphyrin conjugates via β-aminoporphyrins
2016
International audience; The synthesis of functionalized porphyrins and their conjugates from meso-tetraarylporphyrins through the acylation and the oxidation of beta-aminoporphyrins was investigated. 2,3-Dioxochlorins were prepared by the oxidation of a variety of beta-aminoporphyrins and subsequently used in a condensation reaction with functionalized aromatic aldehydes and ammonium acetate to form beta-functionalized porphyrins bearing a fused imidazole ring. Under optimized experimental conditions both reactions tolerate various functional groups and afford the products in an appropriate overall yield. The mildness and usefulness of this methodology are illustrated by several examples in…
SULT1A1 gene deletion in BRCA2-associated male breast cancer: a link between genes and environmental exposures?
2013
SULT1A1, a member of sulfotransferase superfamily, is a drug and hormone metabolizing enzyme involved in the metabolism of a variety of potential mammary carcinogens of endogenous and exogenous origin. Interestingly, the metabolic activity of SULT1A1 can be affected by varia- tions in gene copy number. Male Breast Cancer (MBC) is a rare disease and less investigated disease compared to female BC (FBC). As in FBC, the concurrent effects of genetic risk factors, particularly BRCA2 mutations, increased exposure to estrogens and environmental carcinogens play a relevant role in MBC. By quantitative real-time PCR with TaqMan probes, we investigated the presence of SULT1A1 gene copy number variat…
Constraining the pass-band of future space-based coronagraphs for observations of solar eruptions in the FeXIV 530.3 nm “green line”
2017
This research has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 647214) and from the UK Science and Technology Facilities Council. Observations of the solar corona in the FeXIV 530.3 nm “green line” have been very important in the past, and are planned for future coronagraphs on-board forthcoming space missions such as PROBA-3 and Aditya. For these instruments, a very important parameter to be optimized is the spectral width of the band-pass filter to be centred over the “green line”. Focusing on solar eruptions, motions occurring along the line of sight will Doppler shift the line prof…
Latgaliešu rakstu valodas prievārdu da, iz, apleik atbilsme latviešu literārajā valodā
2021
Bakalaura darba “Latgaliešu rakstu valodas prievārdu da, iz, apleik atbilsme latviešu literārajā valodā” mērķis ir pētīt un salīdzināt no latviešu literārās valodas atšķirīgus prievārdus latgaliešu rakstu valodā. Pētījuma uzdevumi ir teorētisko materiālu apkopošana, valodas piemēru vākšana un analizēšana gan latviešu literārajā, gan latgaliešu rakstu valodā, pētot kā latgaliešu rakstu valodas prievārdi atbilst latviešu literārās valodas prievārdiem. Piemēru atlasei izmantots “Līdzsvarotais mūsdienu latviešu valodas tekstu korpuss 2018”, kā arī “Mūsdienu latgaliešu tekstu korpuss”. Darbs sastāv no ievada, saīsinājumu saraksta, četrām nodaļām, secinājumiem un izmantotās literatūras saraksta.
Finnish-Chinese intercultural negotiation : power positioning and search for common ground
2018
‘Rising China’ is a term that has come to refer to China’s march to being number one, the speed of its economic growth, and its investment around the world during last two decades. In Finland, government agencies have been established to promote investment, trade, and co-operation with China, while regional and local governments are also actively involved. Meanwhile, much of the world is now competing for the attention of China, so the power dynamic is tending to shift in favour of the Chinese. This developing context has been examined in previous studies primarily from the perspectives of politics, economics, and management studies. The overarching aim of this study is to investigate emerg…
Le non-public et la culture. Une étude de cas en banlieue
2012
Photographic exhibitions are organized since 2004 on the banks of the river Marne at Fleury-la-Rivière within the context of an annual event --the Festival de l'Oh!, initiated by the conseil général of the Val-de-Marne. This type of exhibition does not succeed in attracting the "non-public". The representations held by the people concerned can block their interaction with the works presented on such a public space. This study is part of an on-going general study of the non-public and its relation to culture. This is a qualitative study carried out in various "stops" of the Festival de l'Oh! The paper is only concerned with immigrants met in housing estates in the upper districts of Fleury.
Una Qüestió de lògica en un sermó de sant Vicent Ferrer: el tractat De suppositionibus com a eina interpretativa
2019
En els sermons de sant Vicent Ferrer, les referències a qüestions fi losòfi ques ocupen un lloc secundari i subordinat al missatge moral. No obstant això, són prou freqüents i posen de manifest l'alta formació escolàstica del predicador valencià. En un dels sermons trobem un incís que explica una aparent anomalia gramatical en un passatge bíblic; una breu explicació que cobra sentit a partir del contingut del tractat sobre les suposicions dels termes escrit per sant Vicent en els seus anys de formació com a mestre de lògica. Una prova que els seus sermons no es poden entendre plenament sense tenir present les doctrines fi losòfi ques que sostenen el discurs teològic. In the sermons of Saint…
Interactive evolutionary multiobjective optimization with modular physical user interface
2022
© 2022 Copyright held by the owner/author(s). Incorporating the preferences of a domain expert, a decision-maker (DM), in solving multiobjective optimization problems increased in popularity in recent years. The DM can choose to use different types of preferences depending on his/her comfort, requirements, or the problem being solved. Most papers, where preference-based and interactive algorithms have been proposed, do not pay attention to the user interfaces and input devices. If they do, they use character or graphics-based preference input methods. We propose the option of using a physical or tactile input device that gives the DM a better sense of control over providing his/her preferen…
A decomposition approach for multidimensional knapsacks with family-split penalties
2022
The optimization of Multidimensional Knapsacks with Family-Split Penalties has been introduced in the literature as a variant of the more classical Multidimensional Knapsack and Multi-Knapsack problems. This problem deals with a set of items partitioned in families, and when a single item is picked to maximize the utility, then all items in its family must be picked. Items from the same family can be assigned to different knapsacks, and in this situation split penalties are paid. This problem arises in real applications in various fields. This paper proposes a new exact and fast algorithm based on a specific Combinatorial Benders Cuts scheme. An extensive experimental campaign computational…
Geometry and quasisymmetric parametrization of Semmes spaces
2011
We consider decomposition spaces R 3 /G that are manifold factors and admit defining sequences consisting of cubes-with-handles of finite type. Metrics on R 3 /G constructed via modular embeddings of R 3 /G into a Euclidean space promote the controlled topology to a controlled geometry. The quasisymmetric parametrizability of the metric space R 3 /G×R m by R 3+m for any m ≥ 0 imposes quantitative topological constraints, in terms of the circulation and the growth of the cubes-with-handles, on the defining sequences for R 3 /G. We give a necessary condition and a sufficient condition for the existence of such a parametrization. The necessary condition answers negatively a question of Heinone…