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showing 10 items of 6771 documents

The relationship between type 2 diabetes family history, body composition and blood basal glycemia in sedentary people.

2013

The aim of this study was to verify whether there is a positive correlation between family history to type 2 diabetes mellitus and body mass and composition, and alterations in blood basal glycaemia levels in sedentary male and female. Anthropometric variables, blood parameters, body composition and body surface area were evaluated on 183 male and 237 female sedentary individuals. Participants were classified into two groups: FH(+) (family history positive) and FH(-) (familiar history negative) according to their medical history. The FH(+) group showed higher values of body mass and body surface area than FH(-) group. These differences were statistically significant (p < 0.05) for the femal…

AdultBlood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and MetabolismPhysical exerciseType 2 diabetesBiologyYoung AdultEndocrinologySex Factorstype 2 diabetes exercise healthRisk FactorsInternal medicineDiabetes mellitusSurveys and QuestionnairesInternal MedicinemedicineHumansFamily historyRisk factorBody surface areaFamily HealthType 2 Diabetes MellitusGeneral MedicineAnthropometrymedicine.diseaseEndocrinologyDiabetes Mellitus Type 2Body CompositionFemaleSedentary BehaviorActa diabetologica
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Effects of marathon running on plasma total homocysteine concentrations.

2003

Summary Aims There is evidence of an excess of acute cardiovascular (CV) events in marathon runners. High plasma total homocysteine (tHcy) concentrations are a recognised risk factor for CV events. Therefore, we investigated the changes in plasma tHcy concentrations 24 h before and after a marathon race. Methods and results Twenty-two non-professional male athletes, mean age 35.6 (6.6), range 23–49 years, were studied the day before and 24 h after finishing a marathon race. None of the athletes was a carrier of the MTHFR 677TT genotype and no ingestion of supplements of vitamins (B12, B6, folic acid) was allowed. Results Changes in plasma folate and plasma vitamin B12 concentrations were no…

AdultBlood GlucoseMalemedicine.medical_specialtyHomocysteineEndocrinology Diabetes and MetabolismMyocardial InfarctionMedicine (miscellaneous)Fatty Acids NonesterifiedRunningchemistry.chemical_compoundWaist–hip ratioInsulin resistanceFolic AcidRisk FactorsInternal medicineMedicineIngestionHumansInsulinMyocardial infarctionVitamin B12Risk factorHomocysteineNutrition and Dieteticsbiologybusiness.industryWaist-Hip RatioFastingMiddle Agedmedicine.diseaseVitamin B 12EndocrinologychemistryMethylenetetrahydrofolate reductasebiology.proteinBody CompositionInsulin ResistanceCardiology and Cardiovascular MedicinebusinessNutrition, metabolism, and cardiovascular diseases : NMCD
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A low reported energy intake is associated with metabolic syndrome.

2009

Background and aims: Metabolic syndrome (MS) may be associated with the presence of an energy sparing metabolism that predisposes to the excess accumulation of body fat. This study examined the relationship between reported energy intake and obesity in individuals with and without MS. Methods and results: Ninety consecutive non-diabetic obese subjects were divided into two groups based on the presence (MS+: n= 50) or absence (MS-: n= 40) of metabolic syndrome. The study design was cross-sectional. The three-day food record method was used to assess the subjects' usual energy intake and the Diet Readiness Test (DRT) was also administered. Compared to the MS- group, the MS+ group had a signif…

AdultBlood GlucoseMalemedicine.medical_specialtyMetabolic syndrome energy intake obesityEndocrinology Diabetes and MetabolismBlood PressureBody weightFat massBody Mass IndexEndocrinologyHeart RateInternal medicinemedicineHumansInsulinObesityMetabolic SyndromeInsulin bloodbusiness.industryBody Weightmedicine.diseaseObesityFood recordEndocrinologyBody CompositionLinear ModelsObese subjectsFemaleBasal MetabolismMetabolic syndromebusinessEnergy IntakeBody mass index
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Physical Activity, Fitness, Glucose Homeostasis, and Brain Morphology in Twins

2014

The main aim of the present study (FITFATTWIN) was to investigate how physical activity level is associated with body composition, glucose homeostasis, and brain morphology in young adult male monozygotic twin pairs discordant for physical activity.From a population-based twin cohort, we systematically selected 10 young adult male monozygotic twin pairs (age range, 32-36 yr) discordant for leisure time physical activity during the past 3 yr. On the basis of interviews, we calculated a mean sum index for leisure time and commuting activity during the past 3 yr (3-yr LTMET index expressed as MET-hours per day). We conducted extensive measurements on body composition (including fat percentage …

AdultBlood GlucoseMalemedicine.medical_specialtyPhysical fitnessPopulationMonozygotic twinPhysical Therapy Sports Therapy and RehabilitationMotor ActivityBiology03 medical and health sciencesLeisure Activities0302 clinical medicineInternal medicinemedicineHomeostasisHumansGlucose homeostasisOrthopedics and Sports Medicine030212 general & internal medicinegray matter volumeeducationta315education.field_of_studybody compositionexercisebusiness.industryBrain morphometryBrainta3141Twins MonozygoticMagnetic Resonance ImagingTwin studyPhysical activity levelfitnessEndocrinologyPhysical Fitnessglocosebusiness030217 neurology & neurosurgeryHomeostasisMedicine and Science in Sports and Exercise
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The basal energy expenditure of female athletes vs. sedentary women as related to their family history of type 2 diabetes

2001

The purpose of this study was to investigate the basal metabolic rate (BMR) in 16 professional sportswomen (soccer players) versus 15 sedentary women, as related to the presence (FH+) or absence (FH-) of a family history of type 2 diabetes. The sportswomen, in toto, had a significantly higher BMR than expected from predictive equations (+14.92%). However, the difference was limited only to FH- sportswomen (+18.66%, p<0.0005). FH- sportswomen showed a significantly higher measured BMR than FH+ sportswomen (p<0.005), and FH+ (p=0.058) and than FH- (p<0.05) sedentary women. There were no other significant differences relative to physical, metabolic and plasmatic data between the groups. The sp…

AdultBlood Glucosemedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismEnergetic costPhysical exerciseType 2 diabetesOxygen ConsumptionEndocrinologyDiabetes mellitusInternal medicineSoccerInternal MedicinemedicineHumansInsulinFamily historyExercisebiologybusiness.industryAthletesNon insulin dependent diabetes mellitusGeneral Medicinemedicine.diseasebiology.organism_classificationEndocrinologyDiabetes Mellitus Type 2Basal metabolic rateBody CompositionFemaleBasal MetabolismEnergy MetabolismbusinessSportsActa Diabetologica
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Ethnic differences in serum lipoproteins and their determinants in South African women.

2010

The objective of the study was to characterize ethnic differences in lipid levels and low-density lipoprotein (LDL) particle size and subclasses in black and white South African women and to explore the associations with insulin sensitivity (S(I)), body composition, and lifestyle factors. Fasting serum lipids and LDL size and subclasses, body composition (dual-energy x-ray absorptiometry), and S(I) (frequently sampled intravenous glucose tolerance test) were measured in normal-weight (body mass index25 kg/m(2)) black (n = 15) and white (n = 15), and obese (body mass index30 kg/m(2)) black (n = 13) and white (n = 13) women. Normal-weight and obese black women had lower triglycerides (0.59 +/…

AdultBlood Glucosemedicine.medical_specialtyEndocrinology Diabetes and MetabolismLipoproteinsBlood lipidsBlack PeopleMotor ActivityStatistics NonparametricBody Mass Indexchemistry.chemical_compoundSouth AfricaEndocrinologyHigh-density lipoproteinInternal medicineMedicineHumansInsulinObesityTriglyceridesBlack womenImmunoassayTriglyceridebusiness.industryCholesterolPatient SelectionEndocrinologychemistrySocioeconomic FactorsLow-density lipoproteinBody CompositionRegression Analysislipids (amino acids peptides and proteins)FemaleDietary ProteinsInsulin ResistancebusinessBody mass indexLipoproteinMetabolism: clinical and experimental
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Prolonged breast-feeding protects mothers from later-life obesity and related cardio-metabolic disorders

2011

AbstractObjectiveTo investigate the long-term effects of duration of postpartum lactation on maternal body composition and risk for cardio-metabolic disorders in later life.DesignRetrospective study. Body composition was measured using dual-energy X-ray absorptiometry and serum glucose, insulin and lipids were analysed using enzymatic photometric methods 16–20 years after the last pregnancy. Medical history and lifestyle factors were collected via a self-administered questionnaire. Detailed information regarding weight change patterns during each pregnancy was obtained from personal maternity tracking records.SettingCity of Jyväskylä and surroundings in Central Finland.SubjectsTwo hundred a…

AdultBlood Glucosemedicine.medical_specialtymedicine.medical_treatmentMothersMedicine (miscellaneous)PhysiologyBlood PressureMotor ActivityBody Mass IndexAbsorptiometry PhotonInsulin resistanceSurveys and QuestionnairesInternal medicinemedicineHumansInsulinLactationObesityLife StyleFinlandTriglyceridesRetrospective StudiesMetabolic SyndromePregnancyNutrition and Dieteticsbusiness.industryInsulinBody WeightCholesterol HDLWeight changePublic Health Environmental and Occupational Healthta3141Cholesterol LDLMiddle Agedmedicine.diseaseObesityBreast FeedingBlood pressureEndocrinologyBody CompositionEducational StatusFemaleInsulin ResistanceEnergy IntakebusinessBreast feedingBody mass indexPublic Health Nutrition
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Hormone therapy is associated with better body composition and adipokine/glucose profiles

2012

Objective: The aim of this study was to evaluate the possibility of preventing the metabolic health consequences of postmenopausal hypogonadism with the use of long-term hormone therapy (HT). Methods: We used a monozygotic co-twin control design including 10 twin pairs (aged 56-62 y) discordant for HT (duration of HT, 2-10 y). In addition, 14 premenopausal women (aged 29-35 y) who did not use HT were studied to evaluate the differences in metabolic health between the premenopausal and postmenopausal states. Body composition was determined, and waist-to-hip ratio was used as an estimate for fat distribution. Serum sex steroids, sex hormone-binding globulin, and serum lipid and glucose profil…

AdultBlood Glucosenaisetmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentkehon koostumusCo twin controlAdipose tissueAdipokineCarbohydrate metabolismAdipokinesSex Hormone-Binding GlobulinInternal medicineLeukocytesmedicineHumansRNA MessengerGonadal Steroid HormonesMuscle SkeletalChemokine CCL2kehonkoostumusMetabolic healthkaksostutkimusWaist-Hip Ratiobusiness.industryEstrogen Replacement TherapyadipokoinesObstetrics and Gynecologyta3141Twin studyTwins MonozygoticMiddle Agedadipokiinitmedicine.diseaseLipidsPostmenopauseMenopauseEndocrinologyAdipose TissuePremenopauseEstrogenCase-Control StudiesBody CompositionFemaleHormone therapyInsulin ResistancebusinessMenopause
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Lack of association of cd36 snps with early onset obesity : A meta-analysis in 9,973 european subjects

2011

A recent study suggested that four CD36 polymorphisms (namely rs3211867, rs3211883, rs3211908, and rs1527483) were associated with an increased risk of obesity, an increased BMI and percentage of body fat in European adolescents. We first attempted to confirm these results in three independent case-control genome-wide association studies (GWAS) data totaling 3,509 subjects of French and German origin, but we were unable to find any association of these variants with early onset obesity risk. We then genotyped the four CD36 single-nucleotide polymorphisms (SNPs) in a large population-based study of 4,667 Finnish subjects and we did not replicate any of the recently reported associations with…

AdultCD36 AntigensMalemedicine.medical_specialtyAdolescentGenotypeEndocrinology Diabetes and MetabolismCD36MedizinMedicine (miscellaneous)Single-nucleotide polymorphismGenome-wide association studyLocus (genetics)Polymorphism Single NucleotideWhite PeopleBody Mass IndexYoung AdultEndocrinologyInternal medicineGermanymedicineHumansGenetic Predisposition to DiseaseObesityChildAllelesFinlandGenetic associationGeneticsNutrition and Dieteticsbiologybusiness.industryGenetic VariationMiddle Agedmedicine.diseaseObesityAdipose TissueGenetic LociMeta-analysisCase-Control StudiesMultiple comparisons problembiology.proteinFemaleFrancebusinessGenome-Wide Association Study
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Individual and neighbourhood socioeconomic measures and the risk of non-central nervous system solid tumours in children: A nationwide register-based…

2021

Abstract Background The aetiology for most solid tumours in childhood is largely unknown. The lack of evidence concerns also the relationship between socioeconomic position (SEP) and risk of childhood solid tumours other than in the central nervous system (CNS). We sought to access the association between individual and neighbourhood SEP measures and risk of childhood non-CNS solid tumours in Denmark and to evaluate whether associations varied by measure of SEP, time point of SEP assessment (during pregnancy versus before diagnosis) and tumour type. Methods We conducted a nationwide case-control study based on Danish registry data. We identified all children born in 1980–2013 and diagnosed …

AdultCancer ResearchRegister-based studyAdolescentEpidemiologyDenmarkPopulationCentral Nervous System NeoplasmsArea-based socioeconomic positionDanishYoung Adult03 medical and health sciences0302 clinical medicinePregnancyResidence CharacteristicsRisk FactorsmedicineHumansRegistries030212 general & internal medicineChildeducationSocioeconomic statusNeighbourhood (mathematics)Pregnancyeducation.field_of_studybusiness.industryChildhood solid tumoursInfant NewbornCase-control studyInfantmedicine.diseaselanguage.human_languageCancer registrySocioeconomic positionSocioeconomic FactorsOncologyCase-Control StudiesChild Preschool030220 oncology & carcinogenesislanguageEtiologyFemalebusinessDemographyCancer Epidemiology
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