Search results for "predictor"

showing 10 items of 196 documents

A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature

2009

Objective: To create a genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies of endometrial origin. To define the transcriptomic signature of human endometrial receptivity. Design: Two cohorts of endometrial samples along the menstrual cycle were used: one to select the genes to be included in the customized microarray (endometrial receptivity array [ERA]), and the other to be analyzed by ERA to train the predictor for endometrial dating and to define the transcriptomic signature. A third cohort including pathological endometrial samples was used to train the predictor for pathological classification. Setting: Healthy…

InfertilityMicroarraymedia_common.quotation_subjectpredictorEndometriumBioinformaticsSensitivity and SpecificityTranscriptomeEndometriumPredictive Value of Teststranscriptomic signaturemedicineCluster AnalysisHumansPathologicalMenstrual cycleHydrosalpinxMenstrual Cyclemedia_commonUterine Diseasesbusiness.industryReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingObstetrics and GynecologyReproducibility of Resultsendometrial datingGenomicsmedicine.diseasemedicine.anatomical_structureEndometrial receptivityReproductive MedicineFemaleEndometrial receptivitybusinessmicroarrayInfertility Femalediagnostic tool
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The Impact of Java Applications at Microarchitectural Level from Branch Prediction Perspective

2009

The portability, the object-oriented and distributed programming models, multithreading support and automatic garbage collection are features that make Java very attractive for application developers. The main goal of this paper consists in pointing out the impact of Java applications at microarchitectural level from two perspectives: unbiased branches and indirect jumps/calls, such branches limiting the ceiling of dynamic branch prediction and causing significant performance degradation. Therefore, accurately predicting this kind of branches remains an open problem. The simulation part of the paper mainly refers to determining the context length influence on the percentage of unbiased bran…

JavaComputer Networks and CommunicationsComputer scienceIndirect branchContext (language use)Parallel computingArityBranch predictorComputer Science ApplicationsSoftware portabilityInheritance (object-oriented programming)Computational Theory and MathematicscomputerGarbage collectioncomputer.programming_languageInternational Journal of Computers Communications & Control
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Early and midterm outcomes of bioresorbable vascular scaffolds for ostial coronary lesions: insights from the GHOST-EU registry.

2016

Aims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset, with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term, but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA), left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death, target vessel m…

LCX (29Target lesionMale52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostialp= 0.035)medicine.medical_treatmentMyocardial Infarction304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14Coronary Artery Disease030204 cardiovascular system & hematologyCoronary artery diseasebut their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA)0302 clinical medicineAbsorbable Implants030212 general & internal medicineMyocardial infarctionCircumflexRegistriesTissue Scaffolds32%)Drug-Eluting StentsMiddle AgedThrombosisCoronary VesselsAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subset with higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long term but their safety in this setting remains to be explored. Methods and results: Procedural and 12-month follow-up data from consecutive patients treated with BVS for lesions located at the ostium of the right (RCA) left anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular death target vessel myocardial infarction or target lesion revascularisation. The database included a total of 1549 lesions in 1304 patients with a mean age of 62 +/- 11years. There were 90 ostial lesions (5.8%) in 84 patients (6.4%) located at the ostial RCA (14; 16%) LCX (29; 32%) or LAD (47; 52%). Patients presenting with ostial lesions did not differ from the remaining cohort except for a higher incidence of prior revascularisation. Predilation was performed in 97% of the lesions (vs. 96% in non-ostial p= 0.618) post-dilation in 43% (versus 58% in the non-ostial group p= 0.008). At quantitative coronary angiography treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37] p= 0.035) but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groups respectively log-rank p= 0.005). The device-oriented composite endpoint occurred respectively in 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025 HR 2.65 [1.41-4.97]).OstiumAims: We aimed to investigate the outcomes of bioresorbable vascular scaffolds (BVS) in coronary ostial lesions. Ostial lesions represent a challenging angiographic subsetTreatment Outcomein 12.6% and 4.6% at 12 months (log-rank p= 0.001). Treatment of ostial lesions was an independent predictor of this endpoint (p= 0.0025CardiologyFemale549 lesions in 1medicine.symptomCardiology and Cardiovascular MedicineAdultpost-dilation in 43% (versus 58% in the non-ostial groupmedicine.medical_specialtyor LAD (47HR 2.65 [1.41-4.97])but no difference in minimum lumen diameter existed (p= 0.447). Follow-up data were available at 385 [362-465] days. The 12-month Kaplan-Meier estimated rates of scaffold thrombosis were 4.9% and 2.0% (ostial and non-ostial lesion groupsrespectivelyLesion03 medical and health sciencesPercutaneous Coronary Interventionwith higher event rates compared with non-ostial lesions. BVS might be associated with advantages over the long termleft anterior (LAD) or circumflex (LCX) coronary in 11 European centres were collected. The primary device-oriented endpoint was defined as a combination of cardiovascular deathInternal medicinemedicineHumanstarget vessel myocardial infarction or target lesion revascularisation. The database included a total of 1Agedp= 0.008). At quantitative coronary angiographybusiness.industryPercutaneous coronary interventionp= 0.618)treatment of ostial lesions was associated with higher residual stenosis (30% [23-41] vs. 26% [20-37]log-rank p= 0.005). The device-oriented composite endpoint occurredmedicine.diseaseSurgery16%)businessEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: a meta-analysis of individual patient data

2004

Multicenter randomized trials have shown that once-weekly pegylated interferon (peginterferon) alfa-2a is more efficacious than conventional interferon alfa-2a (IFN) in patients with chronic hepatitis C. We performed a meta-analysis of 1,013 previously untreated patients (from 3 randomized trials) with pretreatment and post-treatment liver biopsies to assess the differences between peginterferon alfa-2a and IFN in terms of their effects on liver histology. Reported values were standardized mean differences (SMD) between patients receiving peginterferon alfa-2a and those receiving IFN (post-treatment value minus baseline value for each group). We used a random-effects model to quantify the a…

Liver CirrhosisMaleCirrhosisFibrosiFemalGastroenterologyPolyethylene Glycolslaw.inventionRandomized controlled trialFibrosislawPegylated interferonChronicInterferon Alfa-2aInterferon Alfa-2bvirus diseasesHepatitis CMiddle AgedAdult; Antiviral Agents; Femal; Hepatitis C; Chronic; Humans; Interferon Alfa-2a; Interferon Alfa-2b; Liver; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Treatment Outcome; eHepatitis CRecombinant ProteinseTreatment OutcomeLiverPredictive value of testsFemalePeginterferon alfa-2amedicine.drugAdultmedicine.medical_specialtyEfficacypegylated interferon-alpha-2bBody-mass indexInterferon alpha-2Antiviral AgentsPredictive Value of TestsInternal medicinemedicineHumansInterferon-alpha therapySteatosiHepatologybusiness.industryInterferon-alphaHepatitis C ChronicHepatologymedicine.diseaseImmunologybusinessPredictor
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Positive Teacher Affect and Maternal Support Facilitate Adjustment After the Transition to First Grade

2016

This longitudinal study, conducted among a sample of Finnish primary-school children, examined the proposition that a single high-quality relationship (either with a teacher or a parent) can buffer against adjustment problems. Teachers rated the externalizing problems and prosocial behaviors of 378 children in Grade 1 and again in Grade 2. Relationship measures gathered in Grade 1 included teacher reports of positive affect for the child and mother reports of support for the child. The results supported our proposition by showing that for child adjustment after the transition to primary school it was critical to have at least one high-quality relationship either with a teacher or a parent. …

Longitudinal studyScreening testeducationPredictor variablesAffect (psychology)EducationDevelopmental psychologymaternal supportmental disordersDevelopmental and Educational Psychology0501 psychology and cognitive sciencesfirst gradePath analysis (statistics)Finlandsäätöteacher affect05 social sciencesBehavior change050301 educationprimary-schoolsChild developmentProsocial behaviorPsychology0503 educationSocial Sciences (miscellaneous)050104 developmental & child psychologyMerrill-Palmer Quarterly
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Sociodemographic and behavioural correlates of lifetime number of sexual partners: findings from the English Longitudinal Study of Ageing.

2018

BackgroundNo current data are available on correlates of lifetime sexual partners at older ages. This study aimed to explore correlates of the lifetime number of sexual partners in a sample of older adults.MethodData were from 3054 men and 3867 women aged ≥50 years participating in the English Longitudinal Study of Ageing. Participants reported their lifetime number of sexual partners and a range of sociodemographic characteristics and health behaviours. Multivariable multinomial logistic regression was used to examine correlates of lifetime number of sexual partners, with analyses performed separately for men and women and weighted for non-response.ResultsYounger age, being separated/divor…

Longitudinal studyYounger ageSocial Sciences and HumanitiesSocial Sciences (SOC)Sosyal Bilimler ve Beşeri BilimlerEthnic groupOBSTETRICS & GYNECOLOGYSağlık BilimleriDoğum ve JinekolojiClinical Medicine (MED)SOCIAL SCIENCES BIOMEDICAL0302 clinical medicineSociologyKADIN HASTALIKLARI & DOĞUMSurgery Medicine SciencesKlinik Tıp (MED)030212 general & internal medicineHomosexuality1506older adultsmedia_commonMultinomial logistic regressionKlinik TıpObstetrics and GynecologyGeneral Social SciencesKadın Hastalıkları ve DoğumTıpnumber of sexual partnersCerrahi Tıp BilimleriLife course approachMedicineAİLE ÇALIŞMALARISosyal Bilimler (SOC)0305 other medical sciencePsychologySOSYAL BİLİMLER BİYOMEDİKSELmedia_common.quotation_subjectSOCIAL SCIENCES GENERALnumber of sexual partnerHome Economics03 medical and health sciencesfindings from the English Longitudinal Study of Ageing- BMJ Sex Reprod Health cilt.4 ss.2018-2020 2019 [Jackson S. E. YANG L. López Sánchez G. Veronese N. KOYANAGI A. Grabovac I. SOYSAL P. Smith L. -Sociodemographic and behavioural correlates of lifetime number of sexual partners]Health SciencesGenel Sosyal BilimlerSosyal ve Beşeri BilimlerSocial Sciences & Humanitiessolder adultSosyoloji030505 public healthEv EkonomisiResearchSosyal Bilimler GenelCLINICAL MEDICINEFormer SmokerpredictorsReproductive MedicineAgeingFAMILY STUDIESDemographyBMJ sexualreproductive health
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The cross-lagged relations between children’s academic skill development, task-avoidance, and parental beliefs about success.

2011

Abstract This longitudinal study investigated the cross-lagged associations between children’s academic skill development, task-avoidant behaviour in the context of homework, and parental beliefs about their child’s success from kindergarten to Grade 2. The participants were 1267 children. The children’s pre-skills were assessed at the end of the kindergarten year, and math and reading skills at the end of Grade 1 and Grade 2. Parents provided ratings of their beliefs about their children’s school success and task-avoidant behaviour with regard to homework at the end of Grades 1 and 2. The results showed that children’s math and reading skills predicted children’s task-avoidant behaviour re…

Longitudinal studyeducationContext (language use)Predictor variablesSkill developmentbehavioral disciplines and activitiesEducationDevelopmental psychologyMath skillsCross laggedDevelopmental and Educational Psychologyta516PsychologyTask avoidancepsychological phenomena and processesReading skillsta515Learning and Instruction
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Predictors of mothers' and fathers' teaching of reading and mathematics during kindergarten and Grade 1

2010

Abstract The aim of the present longitudinal study was to investigate factors contributing to mothers' and fathers' teaching of reading and mathematics to their children during kindergarten and Grade 1. It was assumed that mothers' and fathers' teaching during kindergarten would be influenced by their socioeconomic status and their own learning difficulties, whereas during Grade 1 by their children's academic performance. A total of 189 mothers and 165 fathers filled in questionnaires regarding their teaching of reading and mathematics twice, once in kindergarten and once in Grade 1. Children's reading and mathematics performance was also examined twice, once in kindergarten and once in Gra…

Longitudinal studymedia_common.quotation_subjecteducationSkill levelPredictor variablesEducationDevelopmental psychologyReading (process)Developmental and Educational PsychologyMathematics educationPsychologyMathematics instructionSocioeconomic statusmedia_commonLearning and Instruction
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Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer : A Population-Based Study

2021

This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent surgical resection for CRC, were reviewed for age-adjusted Charlson comorbidity index (ACCI) including 19 well-defined weighted comorbidities. The impact of ACCI on multimodal management and survival was compared between low (score 0–2), intermediate (score 3) and high ACCI (score ≥ 4) groups. Changes in treatment from 2000 to 2015 were seen next to a major increase of laparoscopic surgery, increased use of adjuvant chemotherapy and an intensified treatment of metastatic dis…

MESOCOLIC EXCISIONPREDICTORCARCINOMASURGERYRcolorectal cancersuolistosyövätCO-MORBIDITY3126 Surgery anesthesiology intensive care radiologyPOSTOPERATIVE MORTALITYGUIDELINESelderlysurvivalArticleLIVER METASTASEScomorbidityCOLON3121 General medicine internal medicine and other clinical medicineMedicinesyöpätaudithenkiinjääminenINDEXikääntyneetkomorbiditeetti
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Predictors of short- and long-term adherence with a Mediterranean-type diet intervention: the PREDIMED randomized trial.

2016

Background: Dietary intervention success requires strong participant adherence, but very few studies have examined factors related to both short-term and long-term adherence. A better understanding of predictors of adherence is necessary to improve the design and execution of dietary intervention trials. This study was designed to identify participant characteristics at baseline and study features that predict short-term and long-term adherence with interventions promoting the Mediterranean-type diet (MedDiet) in the PREvencion con DIeta MEDiterranea (PREDIMED) randomized trial. Methods: Analyses included men and women living in Spain aged 55-80 at high risk for cardiovascular disease. Part…

Male0301 basic medicineGerontologymodelos logísticoscumplimiento del pacienteMediterranean dietHealth BehaviorhumanosPsychological interventionMedicine (miscellaneous)ejercicio físicoDietary predictorsDiet MediterraneanLogistic regressionDieta mediterrànialaw.invention0302 clinical medicine1479-5868Randomized controlled trialRisk FactorslawNuts030212 general & internal medicineconducta sanitariaDietary adherencemediana edadDietoteràpiaancianoBioquímica y tecnologíaNutrition and DieteticsdietaHàbits alimentarisMiddle AgedBiochemistry and technologyCardiovascular DiseasesFemaleDietaWaist Circumferencemedicine.medical_specialtyWaistFood habitsPromoció de la salutenfermedades cardiovascularesPhysical Therapy Sports Therapy and RehabilitationHealth PromotionClinical nutrition:Ciencias de la Salud::Nutrición y dietética [Materias Investigacion]Bioquímica i biotecnologiaShort-term dietary adherence03 medical and health sciencesMediterranean cookingdietary interventionMediterranean dietCuina mediterràniaingesta energéticamedicineHumansfactores de riesgoAdverse effectOlive OilExerciseDieta -- Mediterrània Regió de laAgedconducta alimentaria030109 nutrition & dieteticsperímetro abdominalMediterranean Dietbusiness.industryResearchFeeding BehaviorDietPREDIMED trialnuecesDietary interventionLogistic ModelsHealth promotionSpainPhysical therapyLong-term dietary adherencePatient ComplianceHealth promotionEnergy Intakebusiness:Ciencias de la Salud::Endocrinología [Materias Investigacion]
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