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Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use

2020

Abstract Psychotic patients with a lifetime history of cannabis use generally show better cognitive functioning than other psychotic patients. Some authors suggest that cannabis-using patients may have been less cognitively impaired and less socially withdrawn in their premorbid life. Using a dataset comprising 948 patients with first-episode psychosis (FEP) and 1313 population controls across 6 countries, we examined the extent to which IQ and both early academic (Academic Factor [AF]) and social adjustment (Social Factor [SF]) are related to the lifetime frequency of cannabis use in both patients and controls. We expected a higher IQ and a better premorbid social adjustment in psychotic p…

MalecognitionIntelligenceComorbiditySUBSTANCE USE DISORDERS0302 clinical medicineSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.MedicinePREDICTORSRISKeducationeducation.field_of_studybiologyCognitionMiddle AgedPsychosocial FunctioningsociabilityPsychiatry and Mental healthSchizophreniaFemaleMarijuana UseSocial AdjustmentMENTAL-HEALTHAdultmedicine.medical_specialtyPsychosisAdolescentPopulation1ST EPISODEDRUG-USEpreillnessSettore MED/01 - Statistica MedicaYoung Adult03 medical and health sciencesAGESettore M-PSI/08 - Psicologia ClinicaHumansCognitive skilleducationPsychiatrySettore MED/25 - Psichiatriabusiness.industryCase-control studypreillnebiology.organism_classificationmedicine.diseaseEDUCAÇÃO030227 psychiatryschizophreniaPsychotic DisordersCase-Control StudiesONSETCannabisNEUROCOGNITIONbusinessmarijuanaNeurocognitive030217 neurology & neurosurgeryRegular ArticlesSchizophrenia Bulletin
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