Search results for "prime"
showing 10 items of 853 documents
Rapid and specific detection of F17-related pilin and adhesin genes in diarrheic and septicemic Escherichia coli strains by multiplex PCR
1996
The F17-related adhesins are prevalent in Escherichia coli strains isolated from calves with diarrhea or septicemia and from lambs with nephropathy. The F17 family includes the F17a, F17b, F17c, and F111 fimbriae produced by bovine E. coli strains and the G agglutinin produced by human uropathogenic E. coli strains. An easy and inexpensive multiplex PCR method was developed to detect all the F17-related fimbriae and to identify four subtypes of structural subunit genes and two distinct subfamilies of adhesin genes by only two runs of amplification. A strict correlation was observed between the phenotypic assays and the multiplex PCR method when 166 pathogenic E. coli strains isolated from i…
Optimization of trigeneration systems by Mathematical Programming: Influence of plant scheme and boundary conditions
2015
Abstract The large potential for energy saving by cogeneration and trigeneration in the building sector is scarcely exploited due to a number of obstacles in making the investments attractive. The analyst often encounters difficulties in identifying optimal design and operation strategies, since a number of factors, either endogenous (i.e. related with the energy load profiles) and exogenous (i.e. related with external conditions like energy prices and support mechanisms), influence the economic viability. In this paper a decision tool is adopted, which represents an upgrade of a software analyzed in previous papers; the tool simultaneously optimizes the plant lay-out, the sizes of the main…
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis
2011
Heat shock proteins (HSPs) are necessary for cancer cell survival. We identified a mutant of HSP110 (HSP110ΔE9) in colorectal cancer showing microsatellite instability (MSI CRC), generated from an aberrantly spliced mRNA and lacking the HSP110 substrate-binding domain. This mutant was expressed at variable levels in almost all MSI CRC cell lines and primary tumors tested. HSP110ΔE9 impaired both the normal cellular localization of HSP110 and its interaction with other HSPs, thus abrogating the chaperone activity and antiapoptotic function of HSP110 in a dominant-negative manner. HSP110ΔE9 overexpression caused the sensitization of cells to anticancer agents such as oxaliplatin and 5-fluorou…
"Observed exclusion contours on HVT $\{g_h,g_f\}$ at 5 TeV" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision data c…
2019
Observed 95% exclusion contours in the HVT parameter space $\{g_h,g_f\}$ with $g_f\equiv g_l=g_q$ for a resonance mass of 5 TeV for the dilepton channel. The area outside the curves is excluded.
"Expected exclusion contours on HVT $\{g_h,g_f\}$ at 4 TeV" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision data c…
2019
Expected 95% exclusion contours in the HVT parameter space $\{g_h,g_f\}$ with $g_f\equiv g_l=g_q$ for a resonance mass of 4 TeV for the dilepton channel. The area outside the curves is excluded.
"Expected exclusion contours on HVT $\{g_h,g_f\}$ at 5 TeV" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision data c…
2019
Expected 95% exclusion contours in the HVT parameter space $\{g_h,g_f\}$ with $g_f\equiv g_l=g_q$ for a resonance mass of 5 TeV for the dilepton channel. The area outside the curves is excluded.
"Observed exclusion contours on HVT $\{g_h,g_f\}$ at 4 TeV" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision data c…
2019
Observed 95% exclusion contours in the HVT parameter space $\{g_h,g_f\}$ with $g_f\equiv g_l=g_q$ for a resonance mass of 4 TeV for the dilepton channel. The area outside the curves is excluded.
"Expected exclusion contours on HVT $\{g_h,g_f\}$ at 3 TeV" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision data c…
2019
Expected 95% exclusion contours in the HVT parameter space $\{g_h,g_f\}$ with $g_f\equiv g_l=g_q$ for a resonance mass of 3 TeV for the dilepton channel. The area outside the curves is excluded.
"Observed exclusion contours on HVT $\{g_h,g_f\}$ at 3 TeV" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision data c…
2019
Observed 95% exclusion contours in the HVT parameter space $\{g_h,g_f\}$ with $g_f\equiv g_l=g_q$ for a resonance mass of 3 TeV for the dilepton channel. The area outside the curves is excluded.
"Selection efficiency for spin-0, spin-1 and spin-2 resonances" of "Search for high-mass dilepton resonances using 139 fb$^{-1}$ of $pp$ collision da…
2019
Dielectron and dimuon selection efficiency as a function of pole mass for spin-0, spin-1 and spin-2 resonances. Drell-Yan MC samples are used for the spin-1 efficiencies and correspond to the zero-width signal hypothesis. Spin-0 (spin-2) efficiencies are obtained from dedicated MC samples with relative widths in the range of 0-20% (1-13%) and are averaged over all available width assumptions.