Search results for "priming"

Long-term melodic expectation: The unexpected observation of distant priming effects

2009

The report provides a brief account of an experiment whose control conditions produced interestingly counter-intuitive results. The method adapted priming techniques to explore whether imagining well-known melodies would facilitate perceptual discrimination of congruent compared to incongruent melodic continuations in a syllable identification task. This was shown to be the case, but in a subsequent control experiment, imagining an irrelevant lure melody also showed a priming effect. The persistent priming effect apparently related the target sequence to the aurally presented, nonadjacent opening notes, and not to the intervening mental image. A number of statistical analyses of the pitch …

An untargeted global metabolomic analysis reveals the biochemical changes underlying basal resistance and priming in Solanum lycopersicum, and identi…

2015

n this study, we have used untargeted global metabolomic analysis to determine and compare the chemi-cal nature of the metabolites altered during the infection of tomato plants (cv. Ailsa Craig) with Botry-tis cinerea (Bot)orPseudomonas syringae pv. tomato DC3000 (Pst), pathogens that have different invasionmechanisms and lifestyles. We also obtained the metabolome of tomato plants primed using the naturalresistance inducer hexanoic acid and then infected with these pathogens. By contrasting the metabolomicprofiles of infected, primed, and primed + infected plants, we determined not only the processes or compo-nents related directly to plant defense responses, but also inferred the metabolic…

2014

The role of literal meaning during the construction of meaning that goes beyond pure literal composition was investigated by combining cross-modal masked priming and ERPs. This experimental design was chosen to compare two conflicting theoretical positions on this topic. The indirect access account claims that literal aspects are processed first, and additional meaning components are computed only if no satisfactory interpretation is reached. In contrast, the direct access approach argues that figurative aspects can be accessed immediately. We presented metaphors (These lawyers are hyenas, Experiment 1a & 1b) and producer-for-product metonymies (The boy read Boll, Experiment 2a & 2b) with a…

β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10

2015

Recent studies have demonstrated that β-catenin in DCs serves as a key mediator in promoting both CD4(+) and CD8(+) T-cell tolerance, although how β-catenin exerts its functions remains incompletely understood. Here we report that activation of β-catenin in DCs inhibits cross-priming of CD8(+) T cells by up-regulating mTOR-dependent IL-10, suggesting blocking β-catenin/mTOR/IL-10 signaling as a viable approach to augment CD8(+) T-cell immunity. However, vaccination of DC-β-catenin(-/-) (CD11c-specific deletion of β-catenin) mice surprisingly failed to protect them against tumor challenge. Further studies revealed that DC-β-catenin(-/-) mice were deficient in generating CD8(+) T-cell immunit…

Constituent priming effects: Evidence for preserved morphological processing in healthy old readers

2009

How elderly adults process morphologically complex words is still a matter of controversy. The present study explored whether compound word recognition is affected by ageing. A group of young adults and a group of older healthy adults were tested on a lexical decision task. Compound words were presented primed by their first constituent (book-BOOKSHOP), their second constituent (shop-BOOKSHOP), or by an unrelated word (house-BOOKSHOP). Results revealed that morphological processing is fully preserved in advanced age and that the magnitude of the constituent priming effect was similar for young and older adults.

The Immune Evasion Paradox: Immunoevasins of Murine Cytomegalovirus Enhance Priming of CD8 T Cells by Preventing Negative Feedback Regulation▿

2008

ABSTRACTCytomegaloviruses express glycoproteins that interfere with antigen presentation to CD8 T cells. Although the molecular modes of action of these “immunoevasins” differ between cytomegalovirus species, the convergent biological outcome is an inhibition of the recognition of infected cells. In murine cytomegalovirus, m152/gp40 retains peptide-loaded major histocompatibility complex class I molecules in acis-Golgi compartment, m06/gp48 mediates their vesicular sorting for lysosomal degradation, and m04/gp34, although not an immunoevasin in its own right, appears to assist in the concerted action of all three molecules. Using the Ld-restricted IE1 epitope YPHFMPTNL in the BALB/c mouse m…

Priming effects of an olfactory food cue on subsequent food-related behaviour

2013

International audience; Studies in cognitive psychology have highlighted a link between perception and action, by revealing the non-conscious influence that a cue can have on thinking and doing. The present study aimed at exploring whether an olfactory food cue could have an impact on food choices. We chose fruity odours as olfactory food cues, in order to examine if this kind of olfactory cue could lead individuals to choose fruit and vegetables. In the first experiment, 58 participants were assigned randomly to either a control or a melon-scent condition. In the melon-scent condition, they were unobtrusively exposed to a melon odorant in a waiting room, while in the control condition the …

On the role of the upper part of words in lexical access: evidence with masked priming.

2012

More than 100 years ago, Huey (1908) indicated that the upper part of words was more relevant for perception than the lower part. Here we examined whether mutilated words, in their upper/lower portions (e.g., , , , ), can automatically access their word units in the mental lexicon. To that end, we conducted four masked repetition priming experiments with the lexical decision task. Results showed that mutilated primes produced a sizeable masked repetition priming effect. Furthermore, the magnitude of the masked repetition priming effect was greater when the upper part of the primes was preserved than when the lower portion was preserved –this was the case not only when the mutilated words we…

Dynamic regulation of CD8 T cell tolerance induction by liver sinusoidal endothelial cells.

2010

Abstract Cross-presentation of soluble Ag on MHC class I molecules to naive CD8 T cells by liver sinusoidal endothelial cells (LSECs) leads to induction of T cell tolerance that requires interaction between coinhibitory B7-H1 on LSECs and programmed cell death-1 on CD8 T cells. In this study, we investigate whether cross-presentation of high as well as low Ag concentrations allowed for LSEC-induced tolerance. Ag concentration directly correlated with the cross-presentation capacity of murine LSECs and thus strength of TCR stimulation. Although LSEC cross-presentation at low-Ag concentrations resulted in tolerance, they induced differentiation into effector T cells (CTL) at high-Ag concentra…

Influenze ed effetti della comunicazione politico/mediatica sul cittadino elettore

2009

Influenze ed effetti della comunicazione politico/mediatica sul cittadino elettore - This paper inquire the circular relationship between media, politics and voters examining the theories about the influences of the media on the individuals; media represent sources of knowledge and information about politics and they can be seen as tool of persuasion. Three levels of the influence exerted by media will be described: the dyadic influence, the influence within groups and the influence on individual opinions. Finally the theories about use and rewards offered by media, about media addiction, about the information processing approach and the perspec- tive of social constructivism encompassing i…