Search results for "primmorphs"

showing 2 items of 2 documents

Localization and Characterization of Ferritin in Demospongiae: A Possible Role on Spiculogenesis

2014

Iron, as inorganic ion or as oxide, is widely used by biological systems in a myriad of biological functions (e.g., enzymatic, gene activation and/or regulation). In particular, marine organisms containing silica structures—diatoms and sponges—grow preferentially in the presence of iron. Using primary sponge cell culture from S. domuncula–primmorphs—as an in vitro model to study the Demospongiae spiculogenesis, we found the presence of agglomerates 50 nm in diameter exclusively inside sponge specialized cells called sclerocytes. A clear phase/material separation is observed between the agglomerates and the initial stages of intracellular spicule formation. STEM-HRTEM-EDX analysis of the agg…

SpiculeIronIron oxidePharmaceutical ScienceNanotechnologyFerric CompoundsArticle<i>Suberites domuncula</i>; primmorphs; iron; ferritin; spiculogenesischemistry.chemical_compoundprimmorphsDrug DiscoveryAnimalslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Cells CulturedSclerocyteDiatomsbiologyferritinHematitebiology.organism_classificationSilicon DioxideSuberites domunculaspiculogenesisPoriferaFerritinSuberites domunculaSpongelcsh:Biology (General)chemistryvisual_artFerritinsbiology.proteinBiophysicsvisual_art.visual_art_mediumSuberitesSuberitesMarine Drugs
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The hypothetical ancestral animal the Urmetazoa: Telomerase activity in sponges [Porifera]

2003

Sponges (Porifera) represent the lowest metazoan phylum, characterized by a pronounced plasticity in the determination of cell lineages, and they are the closest related taxon to the hypothetical ancestral animal, the Urmetazoa, from which the metazoan lineages diverged. In a first approach to elucidate the molecular mechanisms controlling the switch from the cell lineage with a putative indefinite growth capacity to senescent, somatic cells, the activity of the telomerase as an indicator for immortality has been determined. The studies were performed with the marine demosponges Suberites domuncula and Geodia cydonium, in vivo with tissue but also in vitro using the primmorph system. Primmo…

suberites domunculaTelomeraseProgrammed cell deathsenescencebiologySomatic cellLineage (evolution)CellGeneral Chemistrybiology.organism_classificationtelomerestelomeraseCell biologyTelomereSuberites domunculaurmetazoa.lcsh:ChemistrySpongeprimmorphsmedicine.anatomical_structurelcsh:QD1-999geodia cydoniummedicinecell lineagesJournal of the Serbian Chemical Society
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