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showing 10 items of 1102 documents
Analytical Methods for the Determination of Perfume-related Substances.
2014
Las fragancias son productos químicos que desprenden un olor agradable y que se utilizan en multitud de productos de consumo a los que confieren su característico aroma. Así, se pueden encontrar en productos cosméticos de todo tipo (tales como perfumes, champús, desodorantes o jabones) y también en productos para el hogar (como detergentes, ambientadores o velas). El uso de productos cosméticos se ha incrementado progresivamente con el paso del tiempo, considerándose un indicador del progreso y bienestar de un país. El reciente Reglamento Europeo sobre productos cosméticos armoniza íntegramente las normas comunitarias a fin de lograr la libre circulación de los productos y garantizar un ele…
Electrochemical performance of activated screen printed carbon electrodes for hydrogen peroxide and phenol derivatives sensing
2019
Screen-printed carbon electrodes (SPCEs) are widely used for the electroanalysis of a plethora of organic and inorganic compounds. These devices offer unique properties to address electroanalytical chemistry challenges and can successfully compete in numerous aspects with conventional carbon-based electrodes. However, heterogeneous kinetics on SPCEs surfaces is comparatively sluggish, which is why the electrochemical activation of inks is sometimes required to improve electron transfer rates and to enhance sensing performance. In this work, SPCEs were subjected to different electrochemical activation methods and the response to H2O2 electroanalysis was used as a testing probe. Changes in to…
Adapted Transfer of Distance Measures for Quantitative Structure-Activity Relationships and Data-Driven Selection of Source Datasets
2012
Quantitative structure–activity relationships are regression models relating chemical structure to biological activity. Such models allow to make predictions for toxicologically relevant endpoints, which constitute the target outcomes of experiments. The task is often tackled by instance-based methods, which are all based on the notion of chemical (dis-)similarity. Our starting point is the observation by Raymond and Willett that the two families of chemical distance measures, fingerprint-based and maximum common subgraph-based measures, provide orthogonal information about chemical similarity. This paper presents a novel method for finding suitable combinations of them, called adapted tran…
DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
2019
Structural DNA nanotechnology provides a viable route for building from the bottom-up using DNA as construction material. The most common DNA nanofabrication technique is called DNA origami, and it allows high-throughput synthesis of accurate and highly versatile structures with nanometer-level precision. Here, it is shown how the spatial information of DNA origami can be transferred to metallic nanostructures by combining the bottom-up DNA origami with the conventionally used top-down lithography approaches. This allows fabrication of billions of tiny nanostructures in one step onto selected substrates. The method is demonstrated using bowtie DNA origami to create metallic bowtie-shaped an…
Bounded Seed-AGI
2014
Four principal features of autonomous control systems are left both unaddressed and unaddressable by present-day engineering methodologies: (1) The ability to operate effectively in environments that are only partially known at design time; (2) A level of generality that allows a system to re-assess and re-define the fulfillment of its mission in light of unexpected constraints or other unforeseen changes in the environment; (3) The ability to operate effectively in environments of significant complexity; and (4) The ability to degrade gracefully—how it can continue striving to achieve its main goals when resources become scarce, or in light of other expected or unexpected constraining fact…
Evaluation of linkage of bipolar affective disorder to chromosome 18 in a sample of 57 German families.
1999
Previously reported linkage of bipolar affective disorder to DNA markers on chromosome 18 was reexamined in a large sample of German bipolar families. Twenty-three short tandem repeat markers were investigated in 57 families containing 103 individuals with bipolar I disorder (BPI), 26 with bipolar II disorder (BPII), nine with schizoaffective disorder of the bipolar type (SA/BP), and 38 individuals with recurrent unipolar depression (UPR). Evidence for linkage was tested with parametric and non-parametric methods under two definitions of the affected phenotype. Analysis of all 57 families revealed no robust evidence for linkage. Following previous reports we performed separate analyses afte…
Isolation By Distance (IBD) signals in the deep-water rose shrimp Parapenaeus longirostris (Lucas, 1846) (Decapoda, Panaeidae) in the Mediterranean S…
2013
Abstract The identification of boundaries of genetic demes is one of the major goals for fishery management, and few Mediterranean commercial species have not been studied from a genetic point of view yet. The deep-water rose shrimp Parapenaeus longirostris (Lucas, 1846) is one of the most important components of commercial landings in Mediterranean, its fishery aspects have received much attention, regrettably without any concern for the genetic architecture of its populations. The population structure in the central and eastern Mediterranean Sea (captures from six Italian and two Greek landings) has been analysed on the basis of surveys carried out with mitochondrial and AFLP markers. Dat…
Data for nine autosomal STRs markers from Valencia (East Mediterranean coast of the Iberian Peninsula)
2000
Nine STRs loci have been typed in a sample from Valencia, a population from the East Mediterranean coast of the Iberian Peninsula.
Geosphere-biosphere interactions in bio-activity volcanic lakes: Evidences from Hule and Rìo Cuarto (Costa Rica)
2014
Hule and R ́ıo Cuarto are maar lakes located 11 and 18 km N of Poa ́s volcano along a 27 km long fracture zone, in the Central Volcanic Range of Costa Rica. Both lakes are characterized by a stable thermic and chemical stratification and recently they were affected by fish killing events likely related to the uprising of deep anoxic waters to the surface caused by rollover phenomena. The vertical profiles of temperature, pH, redox potential, chemical and isotopic compositions of water and dissolved gases, as well as prokaryotic diversity estimated by DNA fingerprinting and massive 16S rRNA pyrosequencing along the water column of the two lakes, have highlighted that different bio-geochemica…
EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arte…
2010
EULAR/PRINTO/PRES Objectives To validate the previously proposed classification criteria for Henoch-Schonlein purpura (HSP), childhood polyarteritis nodosa (c-PAN), c-Wegener granulomatosis (c-WG) and c-Takayasu arteritis (c-TA).Methods Step 1: retrospective/prospective webdata collection for children with HSP, c-PAN, c-WG and c-TA with age at diagnosis <= 18 years. Step 2: blinded classification by consensus panel of a representative sample of 280 cases. Step 3: statistical (sensitivity, specificity, area under the curve and.-agreement) and nominal group technique consensus evaluations.Results 827 patients with HSP, 150 with c-PAN, 60 with c-WG, 87 with c-TA and 52 with c-other were compar…