Search results for "problems"
showing 10 items of 620 documents
711 Pancreatic Exocrine Function in Allergic Children
2010
Background and aims: The concentration of human pancreatic elastase1 in faeces reflects exocrine pancreatic function. Patients with allergy may have damaged intestinal mucosa or inflammation within the duodenal mucosa that could be associated with pancreatic dysfunction and disturbed digestion of allergens (that are mainly of protein origin). The aim of the study was to compare pancreatic function in allergic patients and children without allergy. Methods: The total patient sample consisted of 109 children, aged 1-10 yrs (mean age 5.2): 49 children were having allergy while 60 were healthy children or children with minor health problems. Faecal samples were gathered and the activity of huma…
PLAYING-RELATED MUSCULOSKELETAL DISORDERS IN WOODWIND, BRASS AND PERCUSSION PLAYERS: A REVIEW
2010
Performing Arts Medicine is a broad field that includes the study of medical conditions and injuries incurred by dancers, instrument musicians and vocalists. Musicians' playing-related health problems have focused more and more the interest of scientists, researchers, physicians, physiotherapists and, in generally, of health care professionals during the last decades. The most relevant Performing Arts Medicine's literature of approximately the past twenty years has been summarized. Special attention has been given to studies concerning playing-related musculoskeletal conditions of musicians. Overuse syndrome is the most reported diagnosis among instrumental musicians suffering from playing-…
Derivation and validation of a novel bleeding risk score for elderly patients with venous thromboembolism on extended anticoagulation
2017
SummaryExisting clinical scores do not perform well in predicting bleeding in elderly patients with acute venous thromboembolism (VTE). We sought to derive an easy-to-use clinical score to help physicians identify elderly patients with VTE who are at high-risk of bleeding during extended anticoagulation (>3 months). Our derivation sample included 743 patients aged ≥65 years with VTE who were enrolled in a prospective multicenter cohort study. All patients received extended anticoagulation with vitamin K antagonists. We derived our score using competing risk regression, with the time to a first major bleeding up to 36 months of extended anticoagulation as the outcome, and 17 candidate var…
Risk of digestive cancers in a cohort of 69 460 five-year survivors of childhood cancer in Europe: the PanCareSurFup study.
2021
BackgroundSurvivors of childhood cancer are at risk of subsequent primary neoplasms (SPNs), but the risk of developing specific digestive SPNs beyond age 40 years remains uncertain. We investigated risks of specific digestive SPNs within the largest available cohort worldwide.MethodsThe PanCareSurFup cohort includes 69 460 five-year survivors of childhood cancer from 12 countries in Europe. Risks of digestive SPNs were quantified using standardised incidence ratios (SIRs), absolute excess risks and cumulative incidence.Results427 digestive SPNs (214 colorectal, 62 liver, 48 stomach, 44 pancreas, 59 other) were diagnosed in 413 survivors. Wilms tumour (WT) and Hodgkin lymphoma (HL) survivors…
Stroke Care Within the COVID-19 Pandemic—Increasing Awareness of Transient and Mild Stroke Symptoms Needed
2020
Background: The COVID-19 pandemic might affect health care resources and alter patient admission to hospital in case of stroke or transient ischemic attack (TIA). We aim to determine whether the COVID-19 pandemic is affecting utilization of recanalization procedures and numbers of patients with stroke and TIA admitted to a primary care stroke center.Methods: In this retrospective observational study, we compared patients admitted from January 2019 until February 2020 with patients admitted during the COVID-19 pandemic (March/April 2020) in Germany. We included patients with stroke (hemorrhagic or ischemic) or TIA as classified by International Statistical Classification of Diseases and Rela…
Association between oral findings and laboratory tests in children and adolescents undergoing dialysis: A cross- sectional study
2017
Background Diagnosis of oral complications in the dialysis patients is important to prevent potential infections. The aim of this cross-sectional study was to compare oral findings in dialysis patients with healthy individuals and determination of the correlation of these findings and laboratory tests. Material and methods In this cross-sectional study, DMFT, dmft, DI , CI , OHIS , PI, GI and enamel defects were evaluated in 25 hemodialysis patients, 30 peritoneal dialysis patients and 26 healthy individuals. Then the correlation of laboratory tests (including Hemoglobin, Urea, Creatinine, Ca, Na, Ph, K and ALP) and oral findings was determined in each groups using SPSS (Version 16). Data a…
Dysfunctional rearing in community and clinic based populations with eating problems: prevalence and mediating role of psychiatric morbidity
2006
Objective To assess the presence of dysfunctional rearing in adolescent females with ED and the role of psychiatric comorbidity as mediating variable of this relationship. Method Administration of a rearing-attitude questionnaire (EMBU-A) and a standardized psychiatric evaluation. Data from a two-phase epidemiological study and from ED inpatients. Case diagnosis was performed using wide DSM-IV criteria (n = 29). Controls were matched by age and school. Results Significant differences were found between EDs subjects and controls on the scales of emotional warmth, overprotection, and rejection. There were no rearing differences between community cases and hospitalized patients. Paternal rejec…
Projecting the spread of COVID-19 for Germany
2020
We model the evolution of the number of individuals that are reported to be sick with COVID-19 in Germany. Our theoretical framework builds on a continuous time Markov chain with four states: healthy without infection, sick, healthy after recovery or after infection but without symptoms and dead. Our quantitative solution matches the number of sick individuals up to the most recent observation and ends with a share of sick individuals following from infection rates and sickness probabilities. We employ this framework to study inter alia the expected peak of the number of sick individuals in a scenario without public regulation of social contacts. We also study the effects of public regulati…
From Neonatal Intensive Care to Neurocritical Care: Is It Still a Mirage? The Sicilian Multicenter Project
2021
Background. Neonatal brain injury (NBI) can lead to a significant neurological disability or even death. After decades of intense efforts to improve neonatal intensive care and survival of critically ill newborns, the focus today is an improved long-term neurological outcome through brain-focused care. The goal of neuroprotection in the neonatal intensive care unit (NICU) is the prevention of new or worsening NBI in premature and term newborns. As a result, the neonatal neurocritical care unit (NNCU) has been emerging as a model of care to decrease NBI and improve the long-term neurodevelopment in critically ill neonates. Purpose. Neurocritical care (NCC) Sicilian project includes three aca…
Clinical trials in children.
2006
Abstract Randomized controlled clinical trials are felt by the medical community to provide the best evidence. Participation in trials involves the possibility of obtaining benefits but also of suffering some risks. Those risks are often considered unacceptable for children but if clinical trials are not conducted in children, clinicians are forced to extrapolate study data from adults. In 1968 H. Shirkey termed children "therapeutic orphans" because of the lack of adequately tested and labeled drugs available in appropriate formulations. Research involving children entails specific difficulties as the need to study children of different ages, the small number of children affected by certai…