Search results for "procedures"

showing 10 items of 1678 documents

Control Of Organ Transplant-Associated Graft-versus-Host Disease By Activated Host Lymphocyte Infusions

2004

Background Prolonged persistence of donor-derived T cells after organ transplantation has been proposed to improve long-term allograft survival. However, surviving transplant-derived T cells are also able to mediate devastating graft-versus-host disease (GvHD). Currently, GvHD after organ transplantation is usually refractory to conventional therapy and the disease outcome fatal. Methods Graft-reactive host T cells were generated ex vivo from a patient suffering from a severe and refractory liver-transplant-associated GvHD. To control GvHD, activated alloreactive host T cells were repetitively retransferred into the patient (activated host lymphocyte infusion [aHLI]). Results Adoptive trans…

medicine.medical_specialtyAdoptive cell transferLymphocytemedicine.medical_treatmentGraft vs Host Diseasechemical and pharmacologic phenomenaLymphocyte ActivationImmunotherapy AdoptiveSeverity of Illness IndexOrgan transplantationBlood Transfusion AutologousmedicineHumansAgedTransplantationbusiness.industryImmunotherapymedicine.diseaseAdoptive TransferLiver TransplantationTransplantationsurgical procedures operativeGraft-versus-host diseasemedicine.anatomical_structureLymphocyte TransfusionImmunologyFemaleStem cellEpidermolysis BullosabusinessEx vivoTransplantation
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Impact of Right Ventricular Dysfunction on Outcomes After Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation

2021

OBJECTIVES This study sought to assess the impact of right ventricular dysfunction (RVD) as defined by impaired right ventricular-to-pulmonary artery (RV-PA) coupling, on survival after edge-to-edge transcatheter mitral valve repair (TMVR) for severe secondary mitral regurgitation (SMR). BACKGROUND Conflicting data exist regarding the benefit of TMVR in severe SMR. A possible explanation could be differences in RVD. METHODS Using data from the EuroSMR (European Registry on Outcomes in Secondary Mitral Regurgitation) registry, this study compared the characteristics and outcomes of SMR patients undergoing TMVR, according to their RV-PA coupling, assessed by tricuspid annular plane systolic e…

medicine.medical_specialtyAdverse outcomesVentricular Dysfunction Right030204 cardiovascular system & hematology030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePredictive Value of TestsInternal medicinemedicine.arterymedicineHumansRadiology Nuclear Medicine and imagingIn patientCardiac Surgical Procedures610 Medicine & healthMitral regurgitationbusiness.industryMitral Valve InsufficiencyRight ventricular dysfunctionTreatment Outcomemedicine.anatomical_structurePulmonary arteryCardiologyTranscatheter mitral valve repairCardiology and Cardiovascular MedicinebusinessArteryJACC: Cardiovascular Imaging
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The Evolution of Cardiovascular Surgery in Elderly Patient: A Review of Current Options and Outcomes

2014

Due to the increase in average life expectancy and the higher incidence of cardiovascular disease with advancing age, more elderly patients present for cardiac surgery nowadays. Advances in pre- and postoperative care have led to the possibility that an increasing number of elderly patients can be operated on safely and with a satisfactory outcome. Currently, coronary artery bypass surgery, aortic and mitral valve surgery, and major surgery of the aorta are performed in elderly patients. The data available show that most cardiac surgical procedures can be performed in elderly patients with a satisfactory outcome. Nevertheless, the risk for these patients is only acceptable in the absence of…

medicine.medical_specialtyAgingMEDLINElcsh:MedicineDiseaseReview ArticleCardiovascular SystemGeneral Biochemistry Genetics and Molecular BiologyCoronary artery bypass surgerymedicine.arterymedicineMyocardial RevascularizationHumansCardiac Surgical ProceduresAgedAortaGeneral Immunology and Microbiologybusiness.industryIncidence (epidemiology)lcsh:RGeneral MedicineHeart ValveshumanitiesSurgeryCardiac surgeryTreatment OutcomeHemostasisLife expectancybusinessBioMed Research International
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Abnormal Nailfold Capillaries in Patients after Hand Transplantation

2020

Background: The development of graft vasculopathy may play a role in the long-term deterioration of hand grafts. The aim of study was to examine the patterns of the nailfold capillaries in hand transplant recipients. Methods: the study was performed on six patients who received hand transplantation. To normalize for the effect of immunosuppression an age- and sex-matched group of 12 patients with active kidney transplant was selected. As an additional control group, 12 healthy volunteers were recruited. Nailfold videocapillaroscopy was performed in all participants. Additionally, serum concentrations of vascular endothelial growth factor (VEGF) were measured. Results: Videocapillaroscopic e…

medicine.medical_specialtyAngiogenesismedicine.medical_treatmentVEGF receptorsUrologymicrovascular abnormalitieslcsh:Medicinenailfold capillaroscopy030230 surgeryArticle03 medical and health scienceschemistry.chemical_compoundangiogenesis0302 clinical medicineHealthy volunteersmedicineIn patient030203 arthritis & rheumatologybiologyvascular endothelial growth factorbusiness.industrylcsh:RImmunosuppressionGeneral MedicineSerum concentrationVascular endothelial growth factorsurgical procedures operativechemistrybiology.proteinbusinessHand transplantationhand transplantationJournal of Clinical Medicine
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Effect of suturing the femoral portion of a four-strand graft during an ACL reconstruction

2014

Purpose A suture passed along the part of the graft that will be inserted into the femoral tunnel is widely used by surgeons, because it could prevent the graft sliding on the femoral fixation device during pulling from the tibial side. The aim of this study was to evaluate the biomechanical effects of suturing the intratunnel femoral part of the graft during an anterior cruciate ligament (ACL) reconstruction. Methods Bovine digital extensor tendons and tibias were harvested from 20 fresh-frozen mature bovine knees ranging in age from 18 to 24 months. Quadruple-strand bovine tendons were passed through the tibial tunnel and secured distally with a bioabsorbable interference screw. In one ha…

medicine.medical_specialtyAnterior cruciate ligamentTransplantsFemoral fixationSettore MED/33 - Malattie Apparato LocomotoremedicineAnimalsOrthopedics and Sports MedicineFemurAnterior Cruciate LigamentFibrous jointFemoral tunnelAnterior Cruciate Ligament Reconstructionbusiness.industrySuture TechniquesBiomechanicsanterior cruciate ligament ACL reconstruction graft properties biomechanics ACL graftmusculoskeletal systemBiomechanical PhenomenaSurgerysurgical procedures operativemedicine.anatomical_structureAcl graftModels AnimalOrthopedic surgeryCattleSurgerybusinessKnee Surgery, Sports Traumatology, Arthroscopy
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Concept and Treatment of Hydrocephalus in the Greco-Roman and Early Arabic Medicine

2007

In the ancient medical literature hydrocephalus was not often described although its existence and symptomatology were well known. Most detailed descriptions of hydrocephalus including the surgical treatment are extant in the encyclopaedic works on medicine of the physicians Oreibasios and Aetios from Amida from the 4th and 6th centuries AD, respectively. Because of their broad scientific interests, this type of physicians, typical for the late Roman empire, were known as philosophy-physicians (iota alpha tau rho o sigma o phi iota sigma tau alpha iota). They defined hydrocephalus in contrast to our present understanding as a fluid collection excluding abscesses visible as a bulging tumour …

medicine.medical_specialtyArabicNeurosurgeryAutopsyGreek WorldVentricular systemRoman WorldNeurosurgical ProceduresHumansMedicineTextbooks as TopicHistory AncientHistory 15th CenturyIntracranial pressureCaput succedaneumbusiness.industryArab WorldInfant NewbornMeningesInfantGeneral Medicinemedicine.diseaseHistory MedievalIntracranial Hemorrhage Traumaticlanguage.human_languageHydrocephalusSurgerySkullmedicine.anatomical_structureNeurologylanguageSurgeryNeurology (clinical)businessHydrocephalusmin - Minimally Invasive Neurosurgery
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Position Paper on Young Vascular Surgeons Training of the Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS): State of the Art a…

2021

ABSTRACT The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded in 2018, with the aim to promote cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic peripheral artery was selected as the very first topic to be investigated by the federation. In this second paper, different experiences from delegates of participating countries were shared to define common strategies to harmonize, standardize, and optimize education and training in the Vascular Surgery specialty.

medicine.medical_specialtyArterial diseasemedia_common.quotation_subjectVascular SurgerySettore MED/22 - Chirurgia VascolareTraining (civil)Peripheral Arterial DiseaseState (polity)medicineMediterranean SeaHumansTrainingEconomic impact analysisVascular surgery specialtymedia_commonNational healthSurgeonsbusiness.industryMediterranean RegionInternship and ResidencyGeneral MedicineVascular surgeryendovascular surgery; Mediterranean sea; training; vascular surgeryEducation Medical GraduateFamily medicineEndovascular SurgeryPosition paperSurgeryClinical CompetenceCurriculumCardiology and Cardiovascular MedicinebusinessVascular Surgical ProceduresDiabetic AngiopathiesLearning CurveProgram EvaluationSpecialization
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Diagnostic Performance of an Artificial Intelligence System in Breast Ultrasound.

2021

Objectives We study the performance of an artificial intelligence (AI) program designed to assist radiologists in the diagnosis of breast cancer, relative to measures obtained from conventional readings by radiologists. Methods A total of 10 radiologists read a curated, anonymized group of 299 breast ultrasound images that contained at least one suspicious lesion and for which a final diagnosis was independently determined. Separately, the AI program was initialized by a lead radiologist and the computed results compared against those of the radiologists. Results The AI program's diagnoses of breast lesions had concordance with the 10 radiologists' readings across a number of BI-RADS descri…

medicine.medical_specialtyArtificial Intelligence Systemhealth care facilities manpower and servicesConcordanceeducationBreast Neoplasmsassisted diagnosis (CADx)artificial intelligence (AI)030218 nuclear medicine & medical imagingaided detection (CADe)03 medical and health sciencesbreast cancer0302 clinical medicineBreast cancerArtificial Intelligencehealth services administrationmedicineHumansRadiology Nuclear Medicine and imagingMedical diagnosisBreast ultrasound030219 obstetrics & reproductive medicineRadiological and Ultrasound Technologymedicine.diagnostic_testultrasoundbusiness.industryUltrasoundmedicine.diseasebody regionsmachine learningsurgical procedures operativecomputer‐FemaleRadiologyUltrasonography MammarybusinessJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in MedicineReferences
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Postoperative maintenance therapy for inflammatory bowel disease.

2006

. Curr Opin Gastroenterol. 2006 Jul;22(4):377-81. Postoperative maintenance therapy for inflammatory bowel disease. Cottone M, Orlando A, Modesto I. Department of General Medicine, Pneumology and Nutrition Clinic, Palermo University, Palermo, Italy. PURPOSE OF REVIEW: This review will highlight the knowledge gained from studies published in the year 2005 on maintenance treatment after surgery for inflammatory bowel diseases. RECENT FINDINGS: In Crohn's disease the role of smoking in increasing the risk of relapse and recurrence after surgery is confirmed. Ornidazole seems effective in reducing endoscopic recurrence and clinical relapse after surgery. Probiotics do not appear to be effective…

medicine.medical_specialtyAzathioprineInflammatory bowel diseaseEnteral NutritionMaintenance therapymedicineHumansIntensive care medicineDigestive System Surgical Procedurescrohn.post-operative.Postoperative CareCrohn's diseasebusiness.industryProbioticsGastroenterologyRetrospective cohort studyPouchitismedicine.diseaseInflammatory Bowel DiseasesUlcerative colitisSurgeryAnti-Bacterial AgentsParenteral nutritionTreatment OutcomebusinessImmunosuppressive Agentsmedicine.drugCurrent opinion in gastroenterology
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Simulation for training in sinus floor elevation: new surgical bench model

2011

Objectives: to describe a bench model (workshop of abilities) for sinus floor elevation (SFE) training that simulates the surgical environment and to assess its effectiveness in terms of trainees’ perception. Study design: thirty-six randomly selected postgraduate students entered this cross-sectional pilot study and asked to fill in an anonymous, self-applied, 12-item questionnaire about a SFE workshop that included a study guide containing the workshop’s details, supervised practice on a simulated surgical environment, and assessment by means of specific check-lists. Results: Thirtiy-six fresh sheep heads were prepared to allow access to the buccal vestible. Using the facial tuber, third …

medicine.medical_specialtyBench modelStudy guideOral Surgical ProcedureseducationSinus Floor AugmentationPilot ProjectsEducation Dental GraduateSinus floor elevationmedicineAnimalsMedical physicsGeneral DentistryMedian scoreSheep:CIENCIAS MÉDICAS [UNESCO]SurgeryClinical PracticeCross-Sectional StudiesOtorhinolaryngologyModels AnimalUNESCO::CIENCIAS MÉDICASResorbable membranesResearch-ArticleSurgeryOral SurgeryCommunication skillsPsychologyMedicina Oral Patología Oral y Cirugia Bucal
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