Search results for "procedures"

Die Primärstabilität von manuell und roboterassistiert implantierten Hüftendoprothesenstielen: eine biomechanische Untersuchung an Kunstfemora

2004

AIM We investigated the initial stability of cementless stems implanted with robotic milling and conventional manual broaching. METHODS Proximally porous structured stems (G2, ESKA-Implants, Luebeck, Germany) were implanted into synthetic femora. In one group, the femoral cavity was prepared by a CT-based robot (CASPAR, URS-Ortho, Germany) with a high-speed milling head. In the other group, femora were rasped manually with broaches. The broaches had 1 mm proximal press-fit, the robotic cavities 1.5 mm. The implants were exposed to 15 000 loading cycles with 1 000 +/- 500 N. The direction of forces on the implant head were chosen to simulate stair climbing. Internal rotation and translation …

Oral Solid Dosage Form Disintegration Testing — The Forgotten Test

2014

Since its inception in the 1930s, disintegration testing has become an important quality control (QC) test in pharmaceutical industry, and disintegration test procedures for various dosage forms have been described by the different pharmacopoeias, with harmonization among them still not quite complete. However, because of the fact that complete disintegration does not necessarily imply complete dissolution, much more research has been focused on dissolution rather than on disintegration testing. Nevertheless, owing to its simplicity, disintegration testing seems to be an attractive replacement to dissolution testing as recognized by the International Conference on Harmonization guidelines, …

Stability of tacrolimus ophthalmic solution

2017

Purpose The stability of 0.3-mg/mL tacrolimus ophthalmic solution at different storage temperatures was studied. Methods A sterile ophthalmic solution of 0.3 mg/mL tacrolimus was prepared in triplicate under aseptic conditions by diluting tacrolimus in eye drops. Three aliquots of this solution were transferred into polypropylene bottles and stored at 25, 2–8, or −15 to −25 °C. Samples were collected immediately after preparation and at selected time points and assayed in triplicate using high-performance liquid chromatography (HPLC). Samples were also visually examined for macroscopic changes. The 0.3-mg/mL tacrolimus solution was also exposed to acidic treatment and heat to force its degr…

Educational value of surgical videos on YouTube: quality assessment of laparoscopic appendectomy videos by senior surgeons vs. novice trainees

2019

Background To prepare for surgery, surgeons often recur to surgical videos, with YouTube being reported as the preferred source. This study aimed to compare the evaluation of three surgical trainees and three senior surgeons of the 25 most viewed laparoscopic appendectomy videos listed on YouTube. Additionally, we assessed the video conformity to the published guidelines on how to report laparoscopic surgery videos (LAP-VEGaS). Methods Based on the number of visualization, the 25 most viewed videos on laparoscopic appendectomy uploaded on YouTube between 2010 and 2018 were selected. Videos were evaluated on the surgical technical performance (GOALS score), critical view of safety (CVS), and…

Ca(u)se di bellezza / Beauty’s causes

2018

Efficace, come dicono i vocabolari, è sinonimo di adeguato o adatto e sembrerebbe riferirsi ad aspetti funzionali; ma basta poco per accorgersi che li oltrepassa per riguardare questioni più ampie che sono relative ai processi, includendo le premesse e gli esiti, attraversando i metodi e le procedure. Il termine deriva infatti dal latino efficere - che significa fare (facere) del tutto (ex-) - con il valore di fare o produrre, ma anche di portare a compimento, di operare in modo che una cosa produca il suo effetto o che sia di effetto. Sul significato di efficace (nello specifico dell’architettura), attraverso il fascino delle parole e la profondità di senso che esse possiedono, si possono …

Isolation of fibroblasts for coating of meshes for reconstructive surgery: differences between mesh types.

2009

Aims: An extensive colonization of surgical meshes with autologous fibroblasts may reduce complications. Therefore, we aimed to establish a technique that allows isolation and propagation of fibroblasts from vaginal biopsies. Using these cells we tested the applicability of several clinically applied meshes for fibroblast coating. Materials & methods: Fibroblasts were isolated from vaginal tissue after digestion with collagenase. Characterization was performed by immunostaining for cytokeratin 5, 6 and 14, smooth muscle actin and vimentin. A semiquantitative technique was applied to determine the degree of mesh coating 5 h and 5 weeks after seeding of fibroblasts. Seven meshes of diffe…

Differences in Perceived Occupational Stress by Demographic Characteristics, of European Emergency Medical Services Personnel during the COVID-19 Vir…

2021

Objectives: The outbreak of the COVID-19 pandemic has brought commercial, social, and economic consequences in every country that has experienced substantial SARS-CoV-2 infection rates. The complete change in the environment that took place due to the outbreak of the pandemic can lead to stressful situations, especially among healthcare personnel. Material and methods: The research were conducted during the COVID-19 pandemic between the 27 March 2020 and the 20 April 2020. The research included 1984 employees of emergency medical systems in seven European countries. An internet-based questionnaire format was adopted for the study (ΩMc-Donald &gt

Deviations in pedestrian itineraries in urban areas: a method to assess the role of environmental factors

2010

Walking has long been neglected in urban-mobility research, but it is now making its way into numerous studies using various approaches. Empirical data are often processed in well-known models of flow allocation to study the behaviour of pedestrians and to identify their preferences. However, these models assume that route choices are predetermined at the start of each trip and do not admit any possible intervening decision along these trips. We propose to overcome this limitation through a new method for the analysis of pedestrian behaviour. This method, which we call ‘deviation analysis’ consists of (1) identifying the intersections from which a pedestrian has chosen a route longer than …

Endoscope‐microscope combination for endonasal sinus surgery

1998

High-Definition Imaging in Spinal Neuroendoscopy

2010

BACKGROUND Spinal endoscopy is still under controversial discussion. An often acclaimed critic is the poor endoscopic image quality in comparison with the microscope. Since high-definition digital cameras have recently been introduced into spinal neuroendoscopy, the aim of the current study is to examine whether superior image quality has a relevant impact on intraoperativen orientation. MATERIAL AND METHODS A lumbar endoscopic discectomy was recorded simultaneously in High-Definition resolution (HD) and Standard-Definition resolution (SD). 10 experienced spinal surgeons were asked to identify predefined as well as not predefined anatomic structures in HD and SD resolution. Additionally, th…