Search results for "processi"

showing 10 items of 9638 documents

Left hemisphere enhancement of auditory activation in language impaired children

2019

| openaire: EC/H2020/641652/EU//ChildBrain Specific language impairment (SLI) is a developmental disorder linked to deficient auditory processing. In this magnetoencephalography (MEG) study we investigated a specific prolonged auditory response (N250m) that has been reported predominantly in children and is associated with level of language skills. We recorded auditory responses evoked by sine-wave tones presented alternately to the right and left ear of 9–10-year-old children with SLI (n = 10) and children with typical language development (n = 10). Source analysis was used to isolate the N250m response in the left and right hemisphere. In children with language impairment left-hemisphere …

0301 basic medicineMaleneurofysiologialcsh:MedicineSpecific language impairmentAudiologyBrain mapping3124 Neurology and psychiatryActivation pattern0302 clinical medicinesensory processinglcsh:Science10. No inequalityChildspecific language impartmentpathophysiologyBrain MappingMultidisciplinarymedicine.diagnostic_testBrainkuuloLanguage developmentAuditory PerceptionEvoked Potentials AuditorySensory processingFemalePsychologyAuditory perceptionauditory responsemedicine.medical_specialtyauditory evoked potentialModels Neurologicaldevelopmental language disorderNeurophysiologyLateralization of brain functionArticle03 medical and health sciencesmedicineHumansLanguage Development Disordershumankielellinen erityisvaikeuslcsh:RMagnetoencephalographybiological modelmedicine.diseaseDevelopmental disorder030104 developmental biologyhearinglcsh:Q030217 neurology & neurosurgeryScientific Reports
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Study of Consumer Preferences in Regard to the Blonde Orange Cv. Washington Navel “Arancia Di Ribera PDO”

2016

Consumers’ attitude and preferences in regard to food ingre- dients, country of origin, social corporate responsibility toward the environment, and work conditions have changed over the last 10 years. Consumers are getting more educated and there- fore more sensitive around cultivation practices in agriculture and food processing, which increases concerns in regard to production practices in agriculture. Several studies have been conducted on consumers’ preferences about quality food, but not with regard to blonde oranges cv. Washington Navel culti- vated in southern Italy. This quality fruit is a niche product that achieved the Protected Designation of Origin (PDO) certifica- tion for high…

0301 basic medicineMarketing030109 nutrition & dieteticsbusiness.industryCertificationOrange (colour)PurchasingCountry of originCluster Analysis Consumer Preferences Preferences segmentation Purchase behaviour Quality fresh food03 medical and health sciencesGeographyAgricultureSettore AGR/01 - Economia Ed Estimo RuraleFood processingCorporate social responsibilityBusiness and International ManagementMarketingFood qualitybusinessFood Science
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Investigation of antirelaxation wall coatings beyond melting temperatures

2017

We investigate vapor cells with antirelaxation wall coatings by measuring their relaxation properties beyond the melting temperatures and compare with the melting behavior of the coating material as observed with differential scanning calorimetry.

0301 basic medicineMaterials scienceMaterials processingCondensed matter physicsDepolarizationCalorimetryengineering.materialMagnetic field03 medical and health sciences030104 developmental biologyDifferential scanning calorimetryCoatingengineeringPolarization (electrochemistry)Conference on Lasers and Electro-Optics
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Tissue expansion of lung bronchi due to tissue processing for histology – A comparative analysis of paraffin versus frozen sections in a pig model

2019

Tissue shrinking due to fixation and processing is well known. However, the degree of shrinking varies significantly with the tissue type as well as the processing method and is not well studied in various tissues. In daily pathological routine workflow, histological specimens from frozen and paraffin sections are performed from the same tissue. In the present study we compared the thickness of bronchus walls obtained from paraffin and frozen sections.Pig lungs were frozen in ventilated condition in liquid nitrogen and 36 bronchi were isolated after dissection. Frozen sections of 5 μm thickness were performed and the remaining tissue was fixed and embedded in paraffin after fixation in 4% f…

0301 basic medicineMaterials scienceSwinemedicine.medical_treatmentBronchiHaematoxylinSpecimen HandlingPathology and Forensic Medicine03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineAnimalsFrozen SectionsLungFixation (histology)BronchusFrozen section procedureParaffin Embeddingbusiness.industryTissue ProcessingHistologyCell BiologyStaining030104 developmental biologymedicine.anatomical_structurechemistry030220 oncology & carcinogenesisNuclear medicinebusinessTissue expansionPathology - Research and Practice
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Surface structure promoted high-yield growth and magnetotransport properties of Bi2Se3 nanoribbons

2019

AbstractIn the present work, a catalyst-free physical vapour deposition method is used to synthesize high yield of Bi2Se3 nanoribbons. By replacing standard glass or quartz substrates with aluminium covered with ultrathin porous anodized aluminium oxide (AAO), the number of synthesized nanoribbons per unit area can be increased by 20–100 times. The mechanisms of formation and yield of the nanoribbons synthesized on AAO substrates having different arrangement and size of pores are analysed and discussed. It is shown that the yield and average length of the nanoribbons can base tuned by adjustment of the synthesis parameters. Analysis of magnetotransport measurements for the individual Bi2Se3…

0301 basic medicineMaterials scienceYield (engineering)Nanowirelcsh:Medicinechemistry.chemical_elementSubstrate (electronics)TOPOLOGICAL INSULATORArticleInorganic Chemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicineBI2TE3AluminiumMaterials ChemistryElectronic devices[CHIM]Chemical SciencesTopological insulatorsDEPOSITIONlcsh:ScienceNANOWIRESurface statesMultidisciplinaryAnodizingPOROUS ALUMINAlcsh:ROrganic ChemistrySynthesis and processingCondensed Matter PhysicsARRAYS030104 developmental biologychemistryChemical engineeringAluminium oxidelcsh:QLayer (electronics)030217 neurology & neurosurgeryScientific Reports
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Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial

2020

AbstractMyotonic dystrophy type 1 (DM1) is a rare genetic disorder, characterised by muscular dystrophy, myotonia, and other symptoms. DM1 is caused by the expansion of a CTG repeat in the 3’-untranslated region of DMPK. Longer CTG expansions are associated with greater symptom severity and earlier age at onset. The primary mechanism of pathogenesis is thought to be mediated by a gain of function of the CUG-containing RNA, that leads to trans-dysregulation of RNA metabolism of many other genes. Specifically, the alternative splicing (AS) and alternative polyadenylation (APA) of many genes is known to be disrupted. In the context of clinical trials of emerging DM1 treatments, it is important…

0301 basic medicineMicroarrayPhysiologyMicroarraysBioinformaticsBiochemistryMachine Learning0302 clinical medicineMathematical and Statistical TechniquesMedicine and Health SciencesMyotonic DystrophyMuscular dystrophyOligonucleotide Array Sequence AnalysisClinical Trials as TopicMultidisciplinaryMusclesQStatisticsRGenetic disorderMuscle AnalysisBody FluidsNucleic acidsBloodBioassays and Physiological AnalysisTreatment OutcomeGenetic DiseasesPhysical SciencesMedicineRegression AnalysisAnatomyDatabases Nucleic AcidResearch Articlemusculoskeletal diseasesGenetic Markerscongenital hereditary and neonatal diseases and abnormalitiesScienceContext (language use)Linear Regression AnalysisBiostatisticsResearch and Analysis MethodsPolyadenylationMyotonic dystrophyMyotonin-Protein Kinase03 medical and health sciencesmedicineGeneticsHumansRNA MessengerStatistical MethodsLeast-Squares AnalysisGeneClinical GeneticsModels Geneticbusiness.industryAlternative splicingBiology and Life Sciencesmedicine.diseaseMyotoniaAlternative Splicing030104 developmental biologyRNA processingRNAGene expressionbusinessTrinucleotide repeat expansionTrinucleotide Repeat Expansion030217 neurology & neurosurgeryBiomarkersMathematicsForecastingPLoS ONE
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Traditional Norwegian Kveik Are a Genetically Distinct Group of Domesticated Saccharomyces cerevisiae Brewing Yeasts

2018

The widespread production of fermented food and beverages has resulted in the domestication of Saccharomyces cerevisiae yeasts specifically adapted to beer production. While there is evidence beer yeast domestication was accelerated by industrialization of beer, there also exists a farmhouse brewing culture in western Norway which has passed down yeasts referred to as kveik for generations. This practice has resulted in ale yeasts which are typically highly flocculant, phenolic off flavor negative (POF-), and exhibit a high rate of fermentation, similar to previously characterized lineages of domesticated yeast. Additionally, kveik yeasts are reportedly high-temperature tolerant, likely due…

0301 basic medicineMicrobiology (medical)030106 microbiologySaccharomyces cerevisiaelcsh:QR1-502ta3111MicrobiologySaccharomyceslcsh:MicrobiologyDomestication03 medical and health sciencesSaccharomycesDomesticationFermentation in food processingWhole genome sequencingGeneticsbiologybusiness.industryta1183ta1182food and beveragesBrewingbiology.organism_classificationYeastYeast030104 developmental biologyAleKveikFermentationBrewingFermentationbusinessFrontiers in Microbiology
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Caco-2 Invasion by Cronobacter sakazakii and Salmonella enterica Exposed to Drying and Heat Treatments in Dried State in Milk Powder

2017

International audience; Due to the ability of foodborne pathogens to survive in low moisture food, the decontamination of milk powder is an important issue in food protection. The safety of food products is, however, not always insured and the different steps in the processing of food involve physiological and metabolic changes in bacteria. Among these changes, virulence properties may also be affected. In this study, the effect of drying and successive thermal treatments on the invasion capacity of Salmonella Typhimurium, Salmonella Senftenberg, and Cronobacter sakazakii was assessed. Bacteria were dried on milk powder at three different water activity levels (0.25, 0.58, and 0.80) and hea…

0301 basic medicineMicrobiology (medical)SalmonellaWater activity030106 microbiologylcsh:QR1-502medicine.disease_causesurvivalMicrobiologystress responseslcsh:Microbiologyresistancestress03 medical and health sciencesCronobacter sakazakiiListeria monocytogenes[SDV.IDA]Life Sciences [q-bio]/Food engineeringwater activitymedicineFood sciencefoodborne pathogensserovar typhimurium2. Zero hungerbiologybusiness.industry[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringSalmonella entericaCaco-2invasionFood safetybiology.organism_classificationCronobacter sakazakiivirulence030104 developmental biologySalmonella entericaescherichia-coliFood processingenterobacter-sakazakiilisteria-monocytogenesbusinessBacteriaFrontiers in Microbiology
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Mechanisms of Hierarchical Cortical Maturation

2017

Cortical information processing is structurally and functionally organized into hierarchical pathways, with primary sensory cortical regions providing modality specific information and associative cortical regions playing a more integrative role. Historically, there has been debate as to whether primary cortical regions mature earlier than associative cortical regions, or whether both primary and associative cortical regions mature simultaneously. Identifying whether primary and associative cortical regions mature hierarchically or simultaneously will not only deepen our understanding of the mechanisms that regulate brain maturation, but it will also provide fundamental insight into aspects…

0301 basic medicineMini ReviewSensory systemlcsh:RC321-57103 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicinemedicineneocortexpyramidal neurondevelopmentlcsh:Neurosciences. Biological psychiatry. NeuropsychiatryAssociative propertyComputational modelNeocortexmaturationhierarchical maturationBrain maturationInformation processing030104 developmental biologymedicine.anatomical_structureNeural processingCellular modelPsychologyNeuroscience030217 neurology & neurosurgeryNeuroscienceFrontiers in Cellular Neuroscience
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Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycae…

2016

Extracellular vesicles (EVs) that are derived from stem cells are proving to be promising therapeutic options. We herein investigate the therapeutic potential of EVs that have been derived from different stem cell sources, bone-marrow (MSC) and human liver (HLSC), on mesangial cells (MCs) exposed to hyperglycaemia. By expressing a dominant negative STAT5 construct (ΔNSTAT5) in HG-cultured MCs, we have demonstrated that miR-21 expression is under the control of STAT5, which translates into Transforming Growth Factor beta (TGFβ) expression and collagen production. A number of approaches have been used to show that both MSC- and HLSC-derived EVs protect MCs from HG-induced damage via the trans…

0301 basic medicineMolecular biologyCellGene Expressionlcsh:MedicineBiochemistry0302 clinical medicineAnimal CellsChronic Kidney DiseaseMedicine and Health SciencesSTAT5 Transcription FactorRNA Processing Post-Transcriptionallcsh:ScienceSTAT5Energy-Producing OrganellesCells CulturedMultidisciplinarybiologyMesangial cellStem CellsVector ConstructionCell biologyMitochondriaEnzymesmedicine.anatomical_structureBiochemistryNephrology030220 oncology & carcinogenesisMesangial CellsCollagenStem cellCellular TypesCellular Structures and OrganellesOxidoreductasesLuciferaseResearch ArticleCollagen Type IVBioenergeticsDNA constructionModels Biological03 medical and health sciencesExtracellular VesiclesmicroRNAmedicineGene Expression and Vector TechniquesGeneticsHumansVesiclesCell ProliferationMolecular Biology Assays and Analysis TechniquesCell growthMesenchymal stem celllcsh:RBiology and Life SciencesProteinsMesenchymal Stem CellsTransforming growth factor betaCell BiologyResearch and analysis methodsMicroRNAs030104 developmental biologyMolecular biology techniquesGlucoseHyperglycemiabiology.proteinEnzymologylcsh:QCollagensPLoS ONE
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