Search results for "programme"
showing 10 items of 874 documents
Proposer des révisions intersessions aux étudiants de 1ère année : quelles relations avec la réussite aux examens ?
2013
This paper assesses a revision programme proposed to unsuccessful students between the two examination sessions within the framework of the "Plan réussite en Licence" in first year at the University of Burgundy, both in terms of student participation and links with achievement. The low participation of students is not associated with particular student profiles. An analysis of the students' future shows that student participation in the revision programme led to a lower drop-out risk during the second examination session and greater success, but only as regards the examinations of the 2nd semester. It should also be noted that student participation also has positive effects in the mid-term …
Les effets des programmes d'excellence sur l'attractivité des formations en Master et Doctorat
2022
Medium-Term Culture of Primary Oral Squamous Cell Carcinoma in a Three- Dimensional Model: Effects on Cell Survival Following Topical 5-Fluororacile …
2012
Since the activity of several conventional anticancer drugs is restricted by resistance mechanisms and dose-limiting side-effects, the design of formulations for local application on malignant lesions seems to be an efficient and promising drug delivery approach. In this study, the effect of locally applied 5-FU on cell death was evaluated both in a SCC4/HEK001 model and in a newly proposed 3D outgrowth model of oral squamous cell carcinoma (OSCC). Initially, the optimal drug dose was established by delivery of solutions containing different amounts of 5-FU. The solution containing 1% (w/v) of 5-FU resulted effective in inducing cell death with complete eradication of cell colonies. Buccal …
PD‐1‐induced T cell exhaustion is controlled by a Drp1‐dependent mechanism
2022
Programmed cell death‐1 (PD‐1) signaling downregulates the T‐cell response, promoting an exhausted state in tumor‐infiltrating T cells, through mostly unveiled molecular mechanisms. Dynamin‐related protein‐1 (Drp1)‐dependent mitochondrial fission plays a crucial role in sustaining T‐cell motility, proliferation, survival, and glycolytic engagement. Interestingly, such processes are exactly those inhibited by PD‐1 in tumor‐infiltrating T cells. Here, we show that PD‐1pos CD8+ T cells infiltrating an MC38 (murine adenocarcinoma)‐derived murine tumor mass have a downregulated Drp1 activity and more elongated mitochondria compared with PD‐1neg counterparts. Also, PD‐1pos lymphocytic elements in…
Essai de mesure des effets du Plan Réussite en Licence
2012
Le premier cycle à l'université est caractérisé en France par une faible efficacité interne (proportion importante d'échecs et d'abandons notamment). En 2007, les pouvoirs publics annoncent le "Plan Réussite en Licence" (PRL) afin de réduire notamment le taux d'échec en première année. Cet article vise à évaluer l'efficacité des actions menées dans le cadre du PRL sur les résultats obtenus par les étudiants en première année. L'originalité de cette recherche tient non seulement dans le caractère novateur des analyses effectuées (peu de recherches sur l'efficacité du PRL), mais également à la multitude des facteurs de réussite pris en compte simultanément, certains se rapportant aux caractér…
L'évaluation du Plan Réussite en Licence : quelles actions pour quels effets ? : Analyse sur les résultats des étudiants en première année universita…
2013
En ligne sur : http://www.recherches-en-education.net/IMG/pdf/REE-no15.pdf; International audience; Le premier cycle à l'université est caractérisé en France par une faible efficacité interne (proportion importante d'échecs et d'abandons notamment). En 2007, les pouvoirs publics annoncent le " Plan Réussite en Licence " (PRL) afin de réduire notamment le taux d'échec en première année. Cet article vise à évaluer l'efficacité des actions menées dans le cadre du PRL sur les résultats obtenus par les étudiants en première année. L'originalité de cette recherche tient non seulement dans le caractère novateur des analyses effectuées (peu de recherches sur l'efficacité du PRL), mais également à l…
PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells
2005
Abstract Killing of tumor cells by cytotoxic therapies, such as chemotherapy or gamma-irradiation, is predominantly mediated by the activation of apoptotic pathways. Refractoriness to anticancer therapy is often due to a failure in the apoptotic pathway. The mechanisms that control the balance between survival and cell death in cancer cells are still largely unknown. Tumor cells have been shown to evade death signals through an increase in the expression of antiapoptotic molecules or loss of proapoptotic factors. We aimed to study the involvement of PED, a molecule with a broad antiapoptotic action, in human breast cancer cell resistance to chemotherapeutic drugs–induced cell death. We show…
How do employed women perceive the reconciliation of work and family life?
2012
PurposeThe purpose of this paper is to analyze how employed women perceive the reconciliation of work and family life in Denmark, Germany, France, Finland, Great Britain, Sweden and Switzerland. The paper seeks to explore why women in certain countries are more successful in combining family responsibilities with gainful employment.Design/methodology/approachDrawing on data from the International Social Survey Programme (ISSP) 2005, the questions are addressed by applying country specific linear regression analysis at the individual level, correlations at the country level as well as policy analysis.FindingsThe analysis shows that the most important factors influencing employed women's perc…
European Union commitment towards RES market penetration: From the first legislative acts to the publication of the recent guidelines on State aid 20…
2015
Abstract During the last three decades, the European Union (EU) commitment towards the Renewable Energy Sources (RES) market penetration has been very complex, involving several aspects pertaining to the economic and political action of Member States. This paper seeks to overview the historical development of the legislative EU framework, including a description of the main financial programmes established and managed by the EU Directorates General. Moreover, the work will proceed with the picture of some Investment Funds, ad hoc created for RES undertakings, and managed by the European Investment Bank (EIB) in collaboration with the EU or other foreign Bank Institutes. The delicate matter …
Getting support in polarized societies: Income, social networks, and socioeconomic context
2013
AbstractThis paper explores how unequal resources and social and economic polarization affects the size of social networks and their use to access resources. We argue that individual resource position generates divergent expectations with regard to the impact of polarization on the size of networks on one hand, and their usefulness for accessing resources on the other. Social and economic polarization encourages reliance on informal networks, but those at the bottom of the social structure are forced to rely on more extensive networks than the wealthy to compensate for their isolated and underprivileged position. At the same time, social and economic polarization limits the resources the po…