Search results for "programme"

showing 10 items of 874 documents

Frames of digital divide in digitalization policies in Finland, Denmark and Sweden and the legitimacy of the implementing agency

2020

The process whereby digital technologies are integrated to everyday functions of the lives of citizens is commonly referred to as digitalization. While the benefits of utilization of technology are undeniable and manifold, digitalization also causes inequality in society. Digital divide is the academic concept that originally referred to the gap between those who have access to technology and those who do not, but nowadays it is understood as a wider phenomenon that encompasses various inequalities brought about by digitalization. Nordic countries are at the forefront in taking advantage of new technological opportunities, but also for these welfare states digital divide is a concern and go…

Nordic Master Programme in Innovative Governance and Public Management (NORDIG)digital dividelegitimacypolicy framingVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242digitalizationME523
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Between institutions and agency : How tensions shape the trajectory of governance

2020

The Europe 2020 strategy promoted the concept of smart specialization as the future for regional development strategies in Europe. The aim was to improve governance practices within European countries on sub-national levels. Nevertheless, not all regions in the European Union produced smart-specialization strategies within the year 2020. The failure to produce a strategy does not mean that actions were not taken. It is instead that actions were taken within different contexts that greatly affected how the implementation process played out. As such, smart specialization has presented opportunities to study the meaning of place. How the policy concept has been translated into action through e…

Nordic Master Programme in Innovative Governance and Public Management (NORDIG)governancePlace-basedVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242ME523smart specialisation
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Organisational responses to regulatory pressure: A case study of a Norwegian Research University’s strategic compliance to GDPR

2020

Master's thesis in Innovative governance and public management (ME523) This thesis study seeks to test Oliver’s (1991) theory for prediction of Strategic Responses to Institutional Processes, against the case of initial responses taken by a Norwegian research university when faced with General Data Protection Regulation (GDPR) of European Union (EU).This thesis explores how different parts of the same organisation respond to and manage institutional pressure. It uses a case study of a Norwegian research university’s response to the European Union’s General Data Protection Regulation (GDPR). An exploratory case study design frame was used to address the research question, and qualitative dat…

Nordic Master Programme in Innovative Governance and Public Management (NORDIG)institutions of higher educationpressuredata protectionresponsesstrategic planningVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242ME523
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The formal organization structure of research innovation centers: a case-study in search of characteristics and an explanation

2020

Master's thesis in Innovative governance and public management (ME523) This study sheds light on research innovation centers in a Norwegian setting. Research innovation centers are a hybrid of research groups and innovation centers and belong to the higher education (HE) sector. The aim of this study is to identify the formal organization structure oftwo cases of research innovation centers and to find a suitable explanation through the analysis of its institutional pillars, according to W. R. Scott (2014). In a qualitative case-analysis it was found that the two cases share most of their characteristics in the formal organization structure. The main findings in both cases are a) a low leve…

Nordic Master Programme in Innovative Governance and Public Management (NORDIG)research innovation centerscase studyVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242organization theoryME523formal organization structure
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Stimulating and facilitating Norwegian RUME

2016

International audience; MatRIC – Centre for Research, Innovation and Coordination of Mathematics Teaching is a Norwegian centre of excellence in higher education. The centre focuses on innovation in university level mathematics teaching. We foster research in teaching and learning mathematics, especially but not exclusively in the context of innovative practice. MatRIC also seeks to facilitate the networking of university level mathematics teachers within Norway and with the international community. This poster focuses on MatRIC's activity aimed at the development of research in university mathematics education. The poster sets out strands of activity within MatRIC's research programme, typ…

Norway[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationCentre of ExcellenceResearch programme
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The neutron background of the XENON100 dark matter search experiment

2013

TheXENON100 experiment, installed underground at the LaboratoriNazionali del Gran Sasso, aims to directly detect dark matter in the form of weakly interacting massive particles (WIMPs) via their elastic scattering off xenon nuclei. This paper presents a study on the nuclear recoil background of the experiment, taking into account neutron backgrounds from (alpha, n) reactions and spontaneous fission due to natural radioactivity in the detector and shield materials, as well as muon-induced neutrons. Based on MonteCarlo simulations and using measured radioactive contaminations of all detector components, we predict the nuclear recoil backgrounds for the WIMP search results published by theXENO…

Nuclear and High Energy PhysicsParticle physicsLarge Underground Xenon experimentPhysics::Instrumentation and DetectorsDark matterGeant4Astrophysics::Cosmology and Extragalactic AstrophysicsWIMP Argon Programme01 natural sciencesNuclear physicsWIMPNuclear and High Energy Physics Neutron Background Dark Matter Search XENON TPC0103 physical sciencesNeutron[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsNuclear ExperimentGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)ComputingMilieux_MISCELLANEOUSSpontaneous fissionPhysicsElastic scatteringFluxMuons010308 nuclear & particles physicsAstrophysics::Instrumentation and Methods for AstrophysicsDetectorsWeakly interacting massive particlesHigh Energy Physics::ExperimentSimulation
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High-quality computational tools for linear-algebra problems in FEM electromagnetic simulation [EM Programmer's Notebook]

2004

A key ingredient of finite-element analysis programs is the linear-algebra solver, typically either a linear-system solver or an eigensolver. The first part of This work tries to justify why it is important to have recourse to publicly available software for addressing this part of the computation. A number of libraries are mentioned as successful examples that exhibit a series of desirable qualities. Although some of these libraries force the programmer to somewhat change the programming style and may be difficult to learn, the benefits usually pay off the extra effort. The second part of the paper describes one of these libraries in some detail, namely SLEPc, the Scalable Library for Eige…

Numerical linear algebraTheoretical computer sciencebusiness.industryComputer sciencemedia_common.quotation_subjectSolverCondensed Matter Physicscomputer.software_genreProgramming styleSoftwareLinear algebraScalabilityKey (cryptography)Electrical and Electronic EngineeringSoftware engineeringbusinessProgrammercomputermedia_commonIEEE Antennas and Propagation Magazine
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Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer

2020

Abstract Background Immune response against cancer has prognostic impact but its role in gastric cancer is poorly known. The aim of the study was to assess the prognostic significance of immune cell score (CD3+, CD8+), tumour immune escape (PD-L1, PD-1) and immune tolerance (Clever-1). Methods After exclusion of Epstein-Barr virus positive (n = 4) and microsatellite instable (n = 6) tumours, the study included 122 patients with GC undergoing D2 gastrectomy. CD3+ and CD8+ based ICS, PD-L1, PD-1 and Clever-1 expressions were evaluated. Differences in survival were examined using Cox regression adjusted for confounders. The primary outcome was 5-year survival. Results The 5-year overall surviv…

OncologyAdultMaleCancer Researchmedicine.medical_specialtyProgrammed Cell Death 1 ReceptorAdenocarcinomaArticleB7-H1 AntigenImmune toleranceImmunophenotyping03 medical and health sciences0302 clinical medicineImmunophenotypingImmune systemStomach NeoplasmsInternal medicinePD-L1medicineImmune ToleranceHumansAgedbiologyMolecular medicinebusiness.industryProportional hazards modelMacrophagesConfoundingImmunosurveillancemahasyöpäCancerennusteetMiddle Agedmedicine.diseaseOncologyimmuunivaste030220 oncology & carcinogenesisbiology.proteinsyöpätauditfenotyyppiFemaleTumor EscapebusinessCD8Signal TransductionBritish Journal of Cancer
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Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast canc…

2021

Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast cancer (TNBC). We compared the analytical concordance and reproducibility of four clinically relevant PD-L1 assays assessing immune cell (IC) score, tumor proportion score (TPS), and combined positive score (CPS) in TNBC. Primary TNBC resection specimens (n = 104) were stained for PD-L1 using VENTANA SP142, VENTANA SP263, DAKO 22C3, and DAKO 28–8. PD-L1 expression was scored according to guidelines on virtual whole slide images by four trained readers. The mean PD-L1 positivity at IC-score ≥1% and CPS ≥1 ranged between 53% and 75% with th…

OncologyCPS combined positive scoreTC tumor cellsICI immune checkpoint inhibitorTriple Negative Breast NeoplasmsB7-H1 AntigenMedicineHER2 human epidermal growth factor receptor 2Triple-negative breast cancerRC254-282ICC intraclass correlation coefficientbiologyNeoplasms. Tumors. Oncology. Including cancer and carcinogensGeneral MedicineMSI microsatellite instabilityImmunohistochemistrypCR pathological complete responsePFS progression-free survivalImmunohistochemistryOriginal ArticleIC-ScoreIC immune cellsIHC immunohistochemistryProgrammed deathPD-L1medicine.medical_specialtyConcordanceTNBC triple-negative breast cancerOS overall survivalBreast cancerTriple-negative breast cancerPD-L1Internal medicineTPS tumor proportion scoreBiomarkers TumorHumansProgrammed death-ligand 1Reproducibilitybusiness.industryReproducibility of Resultsmedicine.diseaseITT intention to treatCI confidence intervalPD-L1 programmed death-ligand 1biology.proteinSurgeryCPSbusinessKappaTMB tumor mutational burdenBreast
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The combined role of biomarkers and interim PET scan in prediction of treatment outcome in classical Hodgkin's lymphoma: a retrospective, European, m…

2016

BACKGROUND: Early-interim fluorodeoxyglucose (FDG)-PET scan after two ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy courses (PET-2) represents the most effective predictor of treatment outcome in classical Hodgkin's lymphoma. We aimed to assess the predictive value of PET-2 combined with tissue biomarkers in neoplastic and microenvironmental cells for this disease.METHODS: We enrolled 208 patients with classical Hodgkin's lymphoma and treated with ABVD (training set), from Jan 1, 2002, to Dec 31, 2009, and validated the results in a fully matched independent cohort of 102 patients with classical Hodgkin's lymphoma (validation set), enrolled from Jan 1, 2008, to De…

OncologyMaleDenmarkProgrammed Cell Death 1 ReceptorCohort Studies0302 clinical medicineRecurrenceAntineoplastic Combined Chemotherapy ProtocolsTumor MicroenvironmentMedicineTreatment FailureReed-Sternberg CellsHazard ratioHematologyHodgkin DiseaseVinblastineDacarbazineSTAT1 Transcription FactorItalylymphoma PET Hodgkin030220 oncology & carcinogenesisDisease ProgressionbiomarkerFemalemedicine.drugAdultmedicine.medical_specialtyDacarbazineAntigens Differentiation MyelomonocyticSettore MED/08 - Anatomia PatologicaVinblastineDisease-Free Survival03 medical and health sciencesBleomycinAntigens CDInternal medicineHumansRetrospective StudiesFluorodeoxyglucosebusiness.industryRetrospective cohort studyPET scanmedicine.diseaseLymphomaSurgeryABVDReed–Sternberg cellDoxorubicinPositron-Emission TomographyMultivariate Analysisclassical Hodgkin's lymphoma:PolandbusinessBiomarkers030215 immunology
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