Search results for "programme"

showing 10 items of 874 documents

A replication study on the intuitiveness of programming language syntax

2023

AbstractIn this article, we present a replication of an empirical experiment that evaluates intuitiveness and comprehensibility of keywords relating to different concepts in programming languages, originally conducted by Stefik and Gellenbeck. Novice programmers face many barriers when learning programming. One of these barriers is syntax, which for many languages is not designed based on empirical evidence. The purpose of the experiment was to provide more empirical evidence on the subject, to find out if the results of the original experiment can be replicated and if conducting the experiment in an environment where English is not the native language affects the results. The results of ou…

program comprehensionnovice programmersnative language in programmingoppiminenohjelmoijatprogramming languagesäidinkieliohjelmointiSafety Risk Reliability and QualitysyntaxohjelmointikieletSoftwarekorkeakouluopetusSoftware Quality Journal
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CD3+ and CD8+ T-Cell-Based Immune Cell Score and PD-(L)1 Expression in Pulmonary Metastases of Microsatellite Stable Colorectal Cancer

2022

Simple Summary The lung is the second most common site of metastases in colorectal cancer (CRC). The aim of our study was to evaluate the prognostic value of CD3+ and CD8+ T-cell density based immune cell score (ICS) and PD-1/PD-L1 expression in resected pulmonary metastases of microsatellite stable CRC. The T-cell infiltration was higher in the first pulmonary metastases compared to primary tumour. Pulmonary metastases with high ICS had improved survival compared to low ICS after adjusting for confounders. High tumour cell PD-L1 expression was associated with favourable prognosis. Our results might have clinical feasibility in planning future therapies. Abstract The objective of this study…

programmed death 1Cancer Research3122 Cancerscolorectal carcinoma; pulmonary metastases; tumour-infiltrating lymphocytes; programmed death 1; programmed death ligand 1karsinoomatetäpesäkkeetOncologycolorectal carcinomaprogrammed death ligand 11182 Biochemistry cell and molecular biologypulmonary metastasessyöpätaudittumour-infiltrating lymphocyteskeuhkotpaksusuolisyöpä
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Explorer les temporalités urbaines de l'agglomération de Dijon: Une approche activité-centrée de l'Enquête-Ménage-Déplacement

2007

National audience

programmes d'activitésmobilitésEnquête ménage déplacementtemporalités[SHS.GEO] Humanities and Social Sciences/GeographyDijon[SHS.GEO]Humanities and Social Sciences/GeographyComputingMilieux_MISCELLANEOUS[ SHS.GEO ] Humanities and Social Sciences/Geography
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Effects of selected pro-environmental project in the regional development of Poland

2019

Zgodnie z założeniami Strategii Europa 2020 wobec państw członkowskich wyznaczono cele w ramach prowadzonej polityki rozwoju. Równocześnie Polska, jako jeden z beneficjentów programów operacyjnych, korzysta z pomocy finansowej UE, realizując projekty na rzecz środowiska, gospodarki niskoemisyjnej, a szerzej − rozwoju zrównoważonego i trwałego. Celem artykułu jest zidentyfikowanie oddziaływania projektów o charakterze prośrodowiskowym na rozwój województw Polski. Analizie poddano inicjatywy realizowane w ramach programów operacyjnych w okresie programowania 2014-2020. Ponadto określono poziomy rozwoju województw Polski w wybranych latach. Zastosowano taksonomiczne metody badawcze Z. Hellwiga…

projekty prośrodowiskowerozwój regionalnypro-ecological programmeregional developmentprogramy operacyjneoperational programmeBiblioteka Regionalisty
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Promoción de la salud en adolescentes mediante un programa de intervención de mejora de la condición física y del estilo de vida

2011

La adolescencia es una etapa clave para la promoción de estilos de vida saludables, tales como el incremento de la actividad física y la mejora de la condición física. El objetivo de este estudio ha sido conocer el nivel de práctica de actividad física habitual en adolescentes y analizar su influencia en la salud, especialmente cardiovascular. Así como, diseñar y llevar a cabo un programa de intervención de mejora de la condición física y el estilo de vida en esta misma población. Se evaluó, pre-intervención, nivel de práctica de actividad física y tiempo dedicado a actividades sedentarias; y pre- y postintervención, presión arterial, frecuencia cardiaca en reposo, composición corporal, y c…

práctica de actividad físicapracticing physical activityFacultat de Medicinaadolescentesprograma de intervencióncardiovascular healthHigiene en general. Higiene i salut personaladolescentsintervention programme613salud cardiovascular
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Estar al otro lado de la mesa. Profesionales de los servicios públicos de empleo ante los dilemas de la activación laboral

2019

Under the paradigm of activation, the Public Employment Services has been reshaped by two levels of contractualization. On one hand, the collaboration of the administration with a network of agents on the programme scheme that make up the active policies of employment. On the other hand, the unemployed person?s access to a compartmentalized offer of services and individually taking responsibility for finding work. This double contractualization reveals redefinition of lowering public responsibility faced with the problem of unemployment that this activation supposes. This paper analyses how this redesign has an impact on how professionals serve the unemployed population. This lays bare, in …

public employment servicescontractualización:SOCIOLOGÍA [UNESCO]the dilemmas that put pressure on in their daily work and exposes them to the disaffection of its public use. DesempleoBe on the other side of the desk. Public employment services professionals facing the dilemmas of labor activation.activaciónin the case of Andalusiathe collaboration of the administration with a network of agents on the programme scheme that make up the active policies of employment. On the other handUnemployment1137-7038 8537 Arxius de sociologia 558787 2019 41 7605685 Estar al otro lado de la mesa. Profesionales de los servicios públicos de empleo ante los dilemas de la activación laboral Pozo-CuevasUNESCO::SOCIOLOGÍAFederico Under the paradigm of activationthe unemployed person?s access to a compartmentalized offer of services and individually taking responsibility for finding work. This double contractualization reveals redefinition of lowering public responsibility faced with the problem of unemployment that this activation supposes. This paper analyses how this redesign has an impact on how professionals serve the unemployed population. This lays barethe Public Employment Services has been reshaped by two levels of contractualization. On one handactivationservicios públicos de empleocontractualization. 123 133
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The state-of-the-art of collaborative technologies for initial vocational education : a systematic literature review

2018


 
 
 Future workplaces require collaboration skills in which members of different work communities use technologies to solve complex problems. Vocational education and training (VET) programs need to meet the challenge to prepare students to be part of a competent workforce. Particularly initial vocational education is under pressure to develop learners’ collaboration skills and abilities. To date, however, no attempt has been made to perform a comprehensive review of the use of computer-supported collaborative learning (CSCL) technologies across different vocational education settings to account for contextual factors of VET. In this systematic review, 26 published studies …

qualification requirementsVET Vocational Education and Training; Initial Vocational Education and Training; Computer-Supported Collaborative Learning CSCL; Technology-Enhanced LearningVocational trainingSocial SciencesBerufs- und WirtschaftspädagogikReviewLearning achievementComputer based training20100Computer-Supported Collaborative LearningWirkungLiteraturberichtEmpirische BildungsforschungComputingMilieux_COMPUTERSANDEDUCATIONBerufsbildungsforschungSociologyBildung und ErziehungProfessionalisierunglcsh:LC8-6691Soziales LernenLearning environment05 social sciences050301 educationvocational educationCollaborative learningcomputer aided learningVocational Training Adult EducationComputer-assisted instructioncomputerunterstütztes LernenBerufsbildungneue TechnologieComputer-supported collaborative learningErstausbildungVocational educationInitial trainingLernumgebungnew technologyResearch methodEngineering ethicsComputer-mediated communicationlcsh:EducationInhaltsanalyseCooperative learningComputer-aided instructionLernerfolgErziehung Schul- und BildungswesenContext (language use)Cooperative learningEducationBildungswesen quartärer Bereich BerufsbildungKooperatives Lernenddc:370CSCL0502 economics and businessprofessionalizationlearning environmentVocational Education and Trainingddc:330Technology-Enhanced Learningresearch on vocational educationQualifikationsanforderungenForschungsmethodeForschungsstandLiterary reviewlcsh:Special aspects of educationComputingMilieux_THECOMPUTINGPROFESSIONSocial learningSocial learningComputerunterstützter UnterrichtProgrammed instructionBerufsausbildungVET10600Vocational education and traininglcsh:LInitial Vocational Education and Training0503 education050203 business & managementContent analysis
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Aplidin® induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 ph…

2006

Aplidin® is an antitumor agent in phase II clinical trials that induces apoptosis through the sustained activation of Jun N-terminal kinase (JNK). We report that Aplidin® alters glutathione homeostasis increasing the ratio of oxidized to reduced forms (GSSG/GSH). Aplidin® generates reactive oxygen species and disrupts the mitochondrial membrane potential. Exogenous GSH inhibits these effects and also JNK activation and cell death. We found two mechanisms by which Aplidin® activates JNK: rapid activation of Rac1 small GTPase and downregulation of MKP-1 phosphatase. Rac1 activation was diminished by GSH and enhanced by L-buthionine (SR)-sulfoximine, which inhibits GSH synthesis. Downregulatio…

rac1 GTP-Binding ProteinProgrammed cell deathSmall interfering RNAGlutathione reductaseDown-RegulationAntineoplastic AgentsApoptosisBreast NeoplasmsCell Cycle ProteinsBiologyPeptides CyclicImmediate-Early ProteinsMembrane Potentialschemistry.chemical_compoundMiceDownregulation and upregulationDepsipeptidesProtein Phosphatase 1Phosphoprotein PhosphatasesAnimalsHomeostasisHumansMolecular Biologychemistry.chemical_classificationReactive oxygen speciesGlutathione PeroxidaseGlutathione DisulfideJNK Mitogen-Activated Protein KinasesProtein phosphatase 1Dual Specificity Phosphatase 1Cell BiologyGlutathioneCell biologyEnzyme ActivationOxidative StressGlutathione ReductasechemistryMitochondrial MembranesGlutathione disulfideCalciumProtein Tyrosine PhosphatasesReactive Oxygen SpeciesCopperHeLa CellsCell Death and Differentiation
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Human, Technologies and Quality of Education: Proceedings of Scientific Papers, 2020

2020

reading literacy for 6 to 7 year old childrenchaplaincyEnglish language teachersacquisition of the English languageTeacher Training Programme for Character Educationinclusive education (inclusion)higher education internationalizationeducation lawmobile learning gameseducational attainmentFitnessnational identityself-regulated learning skillsphysical culturelearning disabilities:SOCIAL SCIENCES::Social sciences::Education [Research Subject Categories]a child with a hearing impairmentcultural aspect of education
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ES Kosmosa politikas un likumdošanas attīstība: drošības aspekti

2017

Maģistra darbā „Eiropas kosmosa likumdošanas un politikas attīstība: drošības sfērā” tiek aplūkota Eiropas kosmosa politikas un likumdošanas ietvara attīstība drošības rīku nodrošīnājumā ES dalībvalstīm ar ES kosmosa programmu palīdzību. Par tēmas aktualitāti liecina fakts, ka mūsdienu pasaule, kurā dzīvojam ir ļoti mainīga un ir nepieciešams rast tehnoloģiskus risinājumus ārpus ierastās vides, lai uzlabotu Eiropas Savienības iedzīvotāju drošību un aizsardzību. Daudzas no ikdienas norisēm balstās un ir atkarīgas no kosmiskajām sistēmām, kosmosa tehnoloģijām un to attīstības. Arī Eiropas Savienība, kā starptaustiski zināms aktieris globālajā vidē, cenšas apvienot Eiropas valstu juridiskos, t…

sattelite technologiesSecurityEkonomikaSpace programmesSpaceEuropean Union
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