Search results for "programming."

Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells

2010

Historically, our understanding of molecular genetic aspects of human germ cell development has been limited, at least in part due to inaccessibility of early stages of human development to experimentation. However, the derivation of pluripotent stem cells may provide the necessary human genetic system to study germ cell development. In this study, we compared the potential of human induced pluripotent stem cells (iPSCs), derived from adult and fetal somatic cells to form primordial and meiotic germ cells, relative to human embryonic stem cells. We found that ∼5% of human iPSCs differentiated to primordial germ cells (PGCs) following induction with bone morphogenetic proteins. Furthermore, …

Virtual lock-and-key approach: The in silico revival of Fischer model by means of molecular descriptors

2010

Abstract In the last years the application of computational methodologies in the medicinal chemistry fields has found an amazing development. All the efforts were focused on the searching of new leads featuring a close affinity on a specific biological target. Thus, different molecular modeling approaches in simulation of molecular behavior for a specific biological target were employed. In spite of the increasing reliability of computational methodologies, not always the designed lead, once synthesized and screened, are suitable for the chosen biological target. To give another chance to these compounds, this work tries to resume the old concept of Fischer lock-and-key model. The same can …

The Polynominal Approximation in Design of Rectification of the Roadway Overhead Crane

1993

In this chapter a new method for processing surveying results of the overhead crane in horizontal plane is presented.

Co-learning of recursive languages from positive data

1996

The present paper deals with the co-learnability of enumerable families L of uniformly recursive languages from positive data. This refers to the following scenario. A family L of target languages as well as hypothesis space for it are specified. The co-learner is fed eventually all positive examples of an unknown target language L chosen from L. The target language L is successfully co-learned iff the co-learner can definitely delete all but one possible hypotheses, and the remaining one has to correctly describe L.

2019

Abstract This article considers the implementation of a new learning subject ”Technology Comprehension” into lower secondary schools in Denmark, as part of an initiative by the Danish Ministry of Education. The subject consists of learning objectives related to computing, design, and societal reflection and was first introduced as an elective course in 13 schools to investigate how it could be integrated into the Danish education system. We present four key findings based on school visits, interviews, an electronical survey, two questionnaires, and workshops including theme discussions: (1) teachers did not perceive Technology Comprehension as a distinct subject, but rather as a set of skil…

Recognition, Work, Treatment

2017

The article I am going to propose is a reflection on the theme of recognition in working and social contexts, and focuses on problems and troubles people cope with in this historical moment. This is a period during which reciprocity and recognition relationships involving our education and work career seem to have no more value, because the world of work now focuses on involving people in production and does not care about involved subjects' life plans. I also wish to point out risks and sufferance affecting subjects who perceive with always greater precision that they are more and more often oppressed by labor and mind exploitation, rather than considered human resources with a working com…

Towards a Modelization of the elusive Concept of Wisdom using Fuzzy Techniques

2012

After having been a term of reflection in philosophy as well as psychology for ages, the fascination with human wisdom finally reaches the realms of computer science. In comparison to the first philosophical definition attempts, that date back to Aristotle (384 BC – 322BC), the efforts in information science during the late 1980s seem quite recent. Nevertheless have there been astonishing new insights provided by cognitive science since those first formal modelizations were designed – findings that strongly suggest a reconsideration of our current formalization of wisdom in the computer science domain. We suggest to establish a new, integrated view on the concept of wisdom, using the insigh…

Evaluación de la educación digital y digitalización de la evaluación

2021

La evaluación de la educación digital y digitalización de la evaluación son procesos por el que transita tanto la educación digital como la educación digital de emergencia. Aunque el tema de la evaluación, por sí misma, ya es complejo, esta complejidad aumenta cuando media la tecnología digital. Lejos de pensar que se trata de una acción técnica, la evaluación digital y la digitalización de la evaluación, como lo demuestra el contenido de este monográfico, no se reducen a la inserción de sistemas tecnológicos, sino a la comprensión pedagógica de su rol e impacto en los procesos educativos. Los trabajos que conforman este monográfico buscan contribuir, desde el análisis empírico y la reflexi…

Recurrence Quantification Analysis as a Methodological Innovation for School Improvement Research

2021

Contains fulltext : 240653.pdf (Publisher’s version ) (Closed access) School improvement and educational change can be facilitated by learning through reflection, as this allows teachers to discover ways to develop and adapt to change. Higher levels of engagement in reflection have been found to be beneficial, but it is unclear from which everyday routine in engagement in reflection higher levels arise, and thus whether occasions to make knowledge explicit should be organized with a certain constancy. In this study, we therefore used a conceptualization of teacher learning through reflection as a situated and dynamic process in which available environmental information, learning activities,…

Today's news — tomorrow's context: A dynamic model of news processing

1997

We are proposing a feedback model of news processing, assuming that news reception is guided by media input as well as by existing cognitive structures. However, these structures are in turn shaped by former media coverage. In our study we examine viewers’ processing of TV news, comparing objective news content (content analysis) to subjective meaning of news stories (viewer interviews). Results show that viewers interpret information about new events in the context of past events, themselves mainly a reflection of former media coverage.