Search results for "proteoliposomes"

showing 2 items of 2 documents

Immuno-toxicological Evaluation of the Adjuvant Formulations for Experimental Anti-meningococcal Vaccines without Aluminium Hydroxide

2019

International audience; The proteoliposomes and cochleates are used as adjuvants for vaccines since they are potent immune stimulators. However, the hyper stimulation of the immune system provoked by adjuvants can cause immunetoxicological side effects. The present study was carried out to evaluate the toxic and immuno-toxicological effects of new adjuvants for anti-meningococci vaccines based on neo-proteoliposomes (nPL) and neocochleates (nCh), in Balb/c mice that were administered doses of 15 µg each, over periods of 14 days through intramuscular route and three inoculations with the same doses through intranasal route, every 7 days. The Scanning and Transmission Electron Microscopy show…

Materials Science (miscellaneous)medicine.medical_treatmentcochleatesSpleenStimulationMeningococcal vaccineImmunotoxicologyPharmacology010402 general chemistry01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyImmune systemproteoliposomesMaterials ChemistryMedicineGeneral Pharmacology Toxicology and Pharmaceuticsbusiness.industryProcess Chemistry and TechnologyGeneral EngineeringGeneral ChemistryGeneral Medicine0104 chemical sciences3. Good healthimmunotoxicologymedicine.anatomical_structureadjuvantsToxicity[SDE]Environmental SciencesNasal administrationnanoparticlesbusinessAdjuvant

researchProduct

Characterization Of Casein-Loaded Proteoliposomes, Potential Inhibitors In Amyloid Fibrillogenesis

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoCasein liposomes proteoliposomes alzheimer's C elegans in vivo model

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