Search results for "proximal"

showing 10 items of 100 documents

Impact loading history modulates hip fracture load and location : A finite element simulation study of the proximal femur in female athletes

2018

Sideways falls impose high stress on the thin superolateral cortical bone of the femoral neck, the region regarded as a fracture-prone region of the hip. Exercise training is a natural mode of mechanical loading to make bone more robust. Exercise-induced adaptation of cortical bone along the femoral neck has been previously demonstrated. However, it is unknown whether this adaption modulates hip fracture behavior. The purpose of this study was to investigate the influence of specific exercise loading history on fall-induced hip fracture behavior by estimating fracture load and location with proximal femur finite element (FE) models created from magnetic resonance images (MRI) of 111 women w…

02 engineering and technologyFinite element simulationWeight-Bearing0302 clinical medicinemurtumatreisiluuOrthopedics and Sports MedicineFemurOrthodonticsHip fractureluustomedicine.diagnostic_testbiologyProximal femurexerciseRehabilitationfallingfemoral neckta3142lonkkamurtumatBiomechanical Phenomenamedicine.anatomical_structureFemalevahvistaminenAdultFinite Element Analysis0206 medical engineeringBiomedical EngineeringBiophysics030209 endocrinology & metabolismbone strengthYoung Adult03 medical and health sciencesmedicineHumansFemoral neckHip Fracturesbusiness.industryAthletesMagnetic resonance imagingfinite element modelingmedicine.diseasebiology.organism_classification020601 biomedical engineeringAthletesImpact loadingAccidental FallsCortical bonebusinesshuman activitiesJournal of Biomechanics
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A note on best proximity point theory using proximal contractions

2018

In this paper, a reduction technique is used to show that some recent results on the existence of best proximity points for various classes of proximal contractions can be concluded from the corresponding results in fixed point theory.

021103 operations researchApplied MathematicsMathematical analysisBest proximity point0211 other engineering and technologiesproximal contractionfood and beveragesFixed-point theorem02 engineering and technologyFixed point01 natural sciencesPoint theory010101 applied mathematicsProximal contractionReduction (complexity)fixed pointModeling and SimulationGeometry and Topology0101 mathematicsMathematics
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Best proximity point theorems for proximal cyclic contractions

2017

The purpose of this article is to compute a global minimizer of the function $$x\longrightarrow d(x, Tx)$$ , where T is a proximal cyclic contraction in the framework of a best proximally complete space, thereby ensuring the existence of an optimal approximate solution, called a best proximity point, to the equation $$Tx=x$$ when T is not necessarily a self-mapping.

021103 operations researchProximal cyclic contractionApplied Mathematics010102 general mathematicsMathematical analysisBest proximity point0211 other engineering and technologies02 engineering and technologyFunction (mathematics)Fixed pointTopology01 natural sciencesComplete metric spaceCyclic contractionSettore MAT/05 - Analisi MatematicaModeling and SimulationPoint (geometry)Global minimizationGeometry and Topology0101 mathematicsApproximate solutionMathematics
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Tetraspanin CD63 controls basolateral sorting of organic cation transporter 2 in renal proximal tubules.

2016

CD63 is a ubiquitously expressed member of the tetraspanin superfamily. Using a mating-based split-ubiquitin-yeast 2-hybrid system, pull-down experiments, total internal reflection fluorescence microscopy, Forster resonance energy transfer, and biotinylation assays, we found that CD63 interacts with human organic cation transporter 2 (hOCT2), which transports endogenous and exogenous substrates, such as neurotransmitters and drugs in several epithelial cells. CD63 overexpression affects cellular localization of hOCT2 expressed in human embryonic kidney (HEK)293 cells. Studies with CD63-knockout mice indicate that in renal proximal tubules, CD63 determines the insertion of the mouse ortholog…

0301 basic medicineOrganic Cation Transport ProteinsEndosomeEndosomesBiochemistryMadin Darby Canine Kidney CellsKidney Tubules Proximal03 medical and health sciencesMiceDogsTetraspaninGeneticsAnimalsHumansMolecular BiologyCellular localizationEpithelial polarityChemistryTetraspanin 30rab4 GTP-Binding ProteinsHEK 293 cellsCell MembraneOrganic Cation Transporter 2TransporterEpithelial CellsTransfectionCell biologyMice Inbred C57BLProtein Transport030104 developmental biologyHEK293 CellsMembrane proteinBiotechnologyProtein BindingFASEB journal : official publication of the Federation of American Societies for Experimental Biology
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SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in fem…

2021

Contains fulltext : 231702.pdf (Publisher’s version ) (Closed access) Deletion 1p36 (del1p36) syndrome is the most common human disorder resulting from a terminal autosomal deletion. This condition is molecularly and clinically heterogeneous. Deletions involving two non-overlapping regions, known as the distal (telomeric) and proximal (centromeric) critical regions, are sufficient to cause the majority of the recurrent clinical features, although with different facial features and dysmorphisms. SPEN encodes a transcriptional repressor commonly deleted in proximal del1p36 syndrome and is located centromeric to the proximal 1p36 critical region. Here, we used clinical data from 34 individuals…

0301 basic medicineSHARPMaleobesitygenotype-phenotype correlationsAutism Spectrum DisorderPROTEINChromosome DisordersHaploinsufficiencyRNA-Binding ProteinPHENOTYPE CORRELATIONS1p36; distal 1p36 deletion syndrome; DNA methylome analysis; episignature; genotype-phenotype correlations; neurodevelopmental disorder; obesity; proximal 1p36 deletion syndrome; SPEN; X chromosome; Adolescent; Autism Spectrum Disorder; Child; Child Preschool; Chromosome Deletion; Chromosome Disorders; Chromosomes Human Pair 1; Chromosomes Human X; DNA Methylation; DNA-Binding Proteins; Epigenesis Genetic; Female; Haploinsufficiency; Humans; Intellectual Disability; Male; Neurodevelopmental Disorders; Phenotype; RNA-Binding Proteins; Young AdultEpigenesis GeneticX chromosome0302 clinical medicineNeurodevelopmental disorderNeurodevelopmental DisorderIntellectual disabilityMOLECULAR CHARACTERIZATIONdistal 1p36 deletion syndromeChildGenetics (clinical)X chromosomeGeneticsXDNA methylome analysiRNA-Binding ProteinsSPLIT-ENDSHypotoniaDNA-Binding ProteinsPhenotypeAutism spectrum disorderChromosomes Human Pair 1Child PreschoolDNA methylome analysisMONOSOMY 1P36Pair 1SPENFemalemedicine.symptomChromosome DeletionHaploinsufficiencyRare cancers Radboud Institute for Health Sciences [Radboudumc 9]HumanAdolescentDNA-Binding ProteinBiologygenotype-phenotype correlationChromosomes03 medical and health sciencesYoung AdultGeneticSDG 3 - Good Health and Well-beingReportIntellectual DisabilityREVEALSGeneticsmedicineHumansEpigeneticsPreschoolChromosomes Human XNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]1p361p36 deletion syndromeIDENTIFICATIONMUTATIONSproximal 1p36 deletion syndromeDNA Methylationmedicine.diseaseneurodevelopmental disorderGENEepisignature030104 developmental biologyChromosome DisorderNeurodevelopmental Disorders030217 neurology & neurosurgeryEpigenesis
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Therapist activities preceding therapy setbacks in a poor-outcome case

2017

AbstractProgress in psychotherapy is typically irregular, as advances alternate with setbacks. This study investigated the therapist’s activities prior to two main types of setbacks, one involving the client following therapist proposals and one involving the client failing to follow from therapist proposals, in the case of a poor-outcome client treated with a linguistically-oriented kind of cognitive therapy. Setbacks were defined as decreases of at least one level on an index of therapeutic progress, the 8-level Assimilation of Problematic Experiences Scale (APES), in adjacent client passages. Therapist activities were coded in 361 setback episodes that each included a client pre-setback …

050103 clinical psychologyPsychotherapistZone of proximal developmentmedicine.medical_treatment05 social sciencesOutcome (game theory)Setback050106 general psychology & cognitive sciencesPsychiatry and Mental healthClinical PsychologyBalance strategyCognitive therapymedicine0501 psychology and cognitive sciencesPsychologyApplied PsychologyCounselling Psychology Quarterly
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Compensation of Oxygen Transmittance Effects for Proximal Sensing Retrieval of Canopy–Leaving Sun–Induced Chlorophyll Fluorescence

2018

Estimates of Sun–Induced vegetation chlorophyll Fluorescence (SIF) using remote sensing techniques are commonly determined by exploiting solar and/or telluric absorption features. When SIF is retrieved in the strong oxygen (O 2 ) absorption features, atmospheric effects must always be compensated. Whereas correction of atmospheric effects is a standard airborne or satellite data processing step, there is no consensus regarding whether it is required for SIF proximal–sensing measurements nor what is the best strategy to be followed. Thus, by using simulated data, this work provides a comprehensive analysis about how atmospheric effects impact SIF estimations on proximal sensing, regarding: (…

1171 GeosciencesFLUXspectral fitting method (SFM)AIRBORNE010504 meteorology & atmospheric sciencesScience0211 other engineering and technologiesFlux02 engineering and technologyfraunhofer line discriminator (FLD)Surface pressure01 natural sciencesO2 transmittanceAtmospheric radiative transfer codesatmospheric pressureFIELD SPECTROSCOPYTransmittanceAstrophysics::Solar and Stellar AstrophysicsSPACESpectral resolutionAbsorption (electromagnetic radiation)021101 geological & geomatics engineering0105 earth and related environmental sciencesRemote sensingproximal sensing4112 Forestrysun-induced chlorophyll fluorescence (SIF)Atmospheric pressureSTRESS DETECTIONPHOTOSYNTHESISQAtmospheric correctionO-2 transmittanceair temperatureREFLECTANCEsun–induced chlorophyll fluorescence (SIF)Physics::Space Physicssun–induced chlorophyll fluorescence (SIF); proximal sensing; O<sub>2</sub> transmittance; fraunhofer line discriminator (FLD); spectral fitting method (SFM); air temperature; atmospheric pressureLUMINESCENCEGeneral Earth and Planetary SciencesEnvironmental scienceABSORPTION-BANDSAstrophysics::Earth and Planetary AstrophysicsVEGETATIONRemote Sensing
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Accélération de la convergence et algorithme proximal

1995

Nous faisons une première étude de la question de savoir s'il est possible d'accélérer des suites issues de l'algorithme proximal ou de la méthode de l'inverse partiel par des méthodes d'extrapolation.

Accélération de la convergenceInverse partielMéthodes d'extrapolation[ MATH.MATH-NA ] Mathematics [math]/Numerical Analysis [math.NA][MATH.MATH-NA] Mathematics [math]/Numerical Analysis [math.NA][MATH.MATH-NA]Mathematics [math]/Numerical Analysis [math.NA]Algorithme proximalApplication pseudo-contractante
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Dermatomyositis induced by the secretion of Phyllomedusa bicolor or Kambô frog - A case report

2020

The Amazonian Kambô frog, Phyllomedusa bicolor, is commonly known for the potential benefits of its secretion. The Kambô ritual consists in applying the toxin directly to a freshly burnt skin area, since it is believed by natives and shamans to purify and strengthen the body and mind of the user. We describe a 33-year old female with a history of periodic use of Kambô toxin who presented with a 3-week course of asthenia, malaise, myalgia, and proximal muscle weakness predominantly in the lower limbs. She had elevated muscle enzymes and an abnormal electromyography. We used the 2017 European League Against Rheumatism and American College of Rheumatology classification criteria to establish t…

Adult0106 biological sciencesmyalgiamedicine.medical_specialtyProximal muscle weaknessRanidaePhyllomedusa bicolorToxicology01 natural sciencesDermatomyositisMalaise03 medical and health sciencesPrednisoneInternal medicineAnimalsHumansMedicine0303 health sciencesbiologybusiness.industry010604 marine biology & hydrobiology030302 biochemistry & molecular biologyDermatomyositismedicine.diseasebiology.organism_classificationDermatologyRheumatologyFemalemedicine.symptombusinessRheumatismmedicine.drugToxicon
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Setbacks in the process of assimilation of problematic experiences in two cases of emotion-focused therapy for depression

2016

Research on the assimilation model has suggested that psychological change takes place in a sequence of stages punctuated by setbacks, that is, by transient reversals in the developmental course. This study analyzed such setbacks in one good outcome case and one poor outcome case of Emotion-focused therapy (EFT) for depression.Intensive analyses of five transcribed sessions from each case identified 26 setbacks in the good outcome case and 27 in the poor outcome case. The reason for each setback was classified into one of four categories: balance strategy, exceeding the therapeutic zone of proximal development either induced by the therapist (ZPD-T) or induced by the client (ZPD-C), or spon…

Adult050103 clinical psychologyEmotion-Focused TherapyPsychotherapistZone of proximal developmentAssimilation modelSetbacks in psychotherapyOutcome (game theory)Psychological sciences Psychology03 medical and health sciences0302 clinical medicine:Psychology [Social sciences]:Psicologia [Ciências sociais]APESHumans0501 psychology and cognitive sciencesGood outcomeDepression (differential diagnoses)DepressionEmotion focused05 social sciences030227 psychiatrySetbackClinical PsychologyBalance strategyOutcome and Process Assessment Health CareCiências psicológicas PsicologiaFemalePsychologyEmotion-focused therapyProcess research
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