Search results for "psychopathology."

showing 10 items of 197 documents

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

2015

Contains fulltext : 155360.pdf (Publisher’s version ) (Closed access) Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in the world and has received considerable attention regarding health risks and benefits. We conducted a genome-wide (GW) meta-analysis of predominately regular-type coffee consumption (cups per day) among up to 91,462 coffee consumers of European ancestry with top single-nucleotide polymorphisms (SNPs) followed-up in ~30 062 and 7964 coffee consumers of European and African-American ancestry, respectively. Studies from both stages were combined in a trans-ethnic meta-analysis. Confirmed loci were examined for putative functional and b…

INVOLVEMENTNetherlands Twin Register (NTR)GCKR protein humanPROTEINGenome-wide association studyVARIANTSgenetics [Brain-Derived Neurotrophic Factor]chemistry.chemical_compound0302 clinical medicinePolymorphism (computer science)genetics [Adaptor Proteins Signal Transducing]BINDINGBRAINGenetics0303 health sciencesBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDisorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]3. Good healthPsychiatry and Mental healthPhenotypegenetics [Polymorphism Single Nucleotide]/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beinggenetics [Cytochrome P-450 CYP1A2]CaffeineCAFFEINESingle-nucleotide polymorphismBiologyArticle03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingCytochrome P-450 CYP1A2/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_SNPHumansddc:610Allelegenetics [Basic Helix-Loop-Helix Leucine Zipper Transcription Factors]Molecular Biology030304 developmental biologyAdaptor Proteins Signal TransducingMLXIPL protein humanRECEPTORBrain-Derived Neurotrophic FactorCoffeata1182Feeding Behaviorbiology.organism_classificationta3124BDNFchemistryBehavioral medicineDevelopmental Psychopathology030217 neurology & neurosurgeryGLUCOKINASEmetabolism [Coffea]Genome-Wide Association StudyMolecular Psychiatry
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The role of depression and impulsivity in the psychopathology of bulimia nervosa.

2013

Introduction: The study aimed to analyze the role of depression and impulsivity in the psychopathology of bulimia nervosa (BN). Materials and methods: Seventy female patients with DSM-IV BN, purging subtype, were assessed for eating-related symptoms, body dissatisfaction, affective symptoms, impulsivity, and personality traits. Factor analysis and structural equation modeling methods were used for statistical analysis. Results: BN appeared as a condition which incorporated 5 general dimensions: a) binge eating and compensatory behaviours; b) restrictive eating; c) body dissatisfaction; d) dissocial personality traits; and e) a cluster of features which was called "emotional instability" The…

Impulsivitymedicine.medical_specialtyModels PsychologicalImpulsivityStructural equation modelingEmotional InstabilityYoung AdultmedicineHumansBig Five personality traitsPsychiatryBulimia NervosaDepression (differential diagnoses)Depressive DisorderSelf-defeating personalityBinge eatingBulimia nervosaDepressionGeneral Medicinemedicine.diseaseCross-Sectional StudiesBulimia nervosaImpulsive BehaviorFemalemedicine.symptomPsychologyBorderline personalityPsychopathologyClinical psychologyRevista de psiquiatria y salud mental
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Aprendizaje cooperativo on-line a través de foros para la resolución de casos de psicopatología

2021

[EN] Human behaviour and its diversity make it very difficult to distinguish between the abnormal and the normal human behaviour and feelings. Through the subject of Psychopathology, students must acquire theoretical knowledge and apply it in practice to identify psychopathological symptoms and signs in clinical cases. The aim of this work is to present the results of the use of a forum as a cooperative learning space for the resolution of practical cases. The sample is composed of two groups (N1=51; N2=43, both in afternoon timetable) belonging to the subject of Psychopathology of the Faculty of Psychology of the University of Valencia. The teaching material applied was the same except for…

Innovación educativaPsychopathologyCompetencias prácticasEvaluaciónForumAprendizaje colaborativoAssessmentPsicopatologíaCollaborative learningEducación superiorEnseñanza superiorPractical skillsTecnologías y educaciónForo
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The meaning of work and its context: A reinterpretation of bartleby, the scrivener by herman melville

2017

By means of a critical reinterpretation of the famous short story by Herman Melville titled “Bartleby, the Scrivener,” I propose a psycho-anthropological explanation of work behaviors, relationships in work environments, and their psychopathological repercussions. The article notably examines behaviors and work relationships connecting them as outcomes of single individuals' efforts to mentalize ideological–cultural models determining them in a given historical moment. A reductively individualistic interpretation is criticized, which is typically present in clinical and work psychology and ascribes to the single person presumed psychical deficits and exclusively looks in his/her personal hi…

LiteratureReinterpretationwork psychopathologyIdeological cultural models of work relationshipbusiness.industryPhilosophy05 social sciencesContext (language use)Meaning (non-linguistic)030227 psychiatryEpistemology03 medical and health sciencesPhilosophy0302 clinical medicineliterary text psychology0502 economics and businessScrivenerIdeological “cultural models of work relationships; literary text psychology; work psychopathology;Settore M-PSI/06 - Psicologia Del Lavoro E Delle Organizzazionibusiness050203 business & management
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Validation of the German Version of the Power of Food Scale in a General Population Sample

2019

<b><i>Objective:</i></b> The Power of Food Scale (PFS) is a self-report instrument for assessing appetitive motivation in the absence of caloric needs. The study aim was to validate the German PFS version in a large population sample. <b><i>Methods:</i></b> Complete information on all PFS items was available from 2,421 respondents (age ≥14) of a nationally representative sample of the German population. We examined the psychometric properties of the German PFS version and provided population-based normative data. <b><i>Results:</i></b> The 3-factor structure of the original scale was replicated in confirmatory factor an…

Male0301 basic medicineHealth (social science)AnxietyGerman0302 clinical medicineHedonic hungerGermanySurveys and QuestionnairesValidationMedicinelcsh:RC620-627Aged 80 and overeducation.field_of_studyPower of Food ScaleDepressionMiddle AgedConfirmatory factor analysislcsh:Nutritional diseases. Deficiency diseaseslanguageAnxietyFemalemedicine.symptomlcsh:Nutrition. Foods and food supplyResearch ArticlePsychopathologyAdultAdolescentPsychometricsPopulation030209 endocrinology & metabolismSample (statistics)lcsh:TX341-641Feeding and Eating DisordersYoung Adult03 medical and health sciencesPhysiology (medical)HumansTranslationseducationAgedMotivation030109 nutrition & dieteticsbusiness.industryReproducibility of ResultsFeeding Behaviorlanguage.human_languagePatient Health QuestionnaireCross-Sectional StudiesFoodSelf ReportbusinessDemographyGerman versionObesity Facts
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Metabolic, Affective and Neurocognitive Characterization of Metabolic Syndrome Patients with and without Food Addiction. Implications for Weight Prog…

2021

According to the food addiction (FA) model, the consumption of certain types of food could be potentially addictive and can lead to changes in intake regulation. We aimed to describe metabolic parameters, dietary characteristics, and affective and neurocognitive vulnerabilities of individuals with and without FA, and to explore its influences on weight loss progression. The sample included 448 adults (55-75 years) with overweight/obesity and metabolic syndrome from the PREDIMED-Plus cognition sub-study. Cognitive and psychopathological assessments, as well as dietary, biochemical, and metabolic measurements, were assessed at baseline. Weight progression was evaluated after a 3-year follow u…

Male030309 nutrition & dieteticsNeurocognitive statePhysiologyOverweightFood addictionBody Mass IndexFatty Acids Monounsaturated0302 clinical medicineCognitionWeight lossSurveys and QuestionnairesTX341-641media_common2. Zero hunger0303 health sciencesNutrition and DieteticsHàbits alimentarisDepressionfood addictionFatty AcidsMiddle AgedMetabolic syndrome3. Good healthCompulsive behaviorCardiovascular Diseasesneurocognitive stateObesitatFemalemedicine.symptomConducta compulsivaPsychopathologyQuality of lifePsychometricsFood addictionFood habitsmedia_common.quotation_subjectArticlemetabolic syndrome03 medical and health sciencesWeight LossmedicineHumansObesityAgedbusiness.industryNutrition. Foods and food supplyAddictionOverweightmedicine.diseaseObesityDietquality of lifeMetabolic syndromebusinessNeurocognitive030217 neurology & neurosurgeryFood ScienceNutrients
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Differential Change of Borderline Personality Disorder Traits During Dialectical Behavior Therapy for Adolescents

2019

Despite the expansion of treatment options for adults with borderline personality disorder (BPD), research on treatment options for adolescent BPD is scarce. The aim of this study was to investigate the impact of dialectical behavior therapy for adolescents (DBT-A) on the individual trait level as primary outcome; and the frequency of suicide attempts and nonsuicidal self-injury, self-reported BPD core pathology, and general psychopathology as secondary outcomes. Seventy-two adolescents (aged 12–17 years) with full- or subsyndromal BPD were treated with DBT-A (25 single sessions, 20 sessions of skills training), and 13 patients (18.1%) withdrew during treatment. From baseline to post-treat…

MaleAdolescentmedicine.medical_treatmentUncontrolled StudyDialectical Behavior Therapybehavioral disciplines and activities03 medical and health sciencesSkills training0302 clinical medicinePrimary outcomeBorderline Personality Disordermental disordersmedicineHumans0501 psychology and cognitive sciencesChildBorderline personality disorder05 social sciencesTreatment optionsmedicine.diseaseDialectical behavior therapy030227 psychiatryPsychiatry and Mental healthClinical PsychologyGeneral psychopathologyTreatment OutcomeTraitFemalePsychology050104 developmental & child psychologyClinical psychologyJournal of Personality Disorders
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Work careers in adults separated temporarily from their parents in childhood during World War II.

2019

Introduction: Traumatic experiences, such as separation from parents in childhood causing early life stress (ELS) may increase the risk of adverse long-term health outcomes and biological age-related changes. This may have an impact on work career. Our aim was to examine long term consequences of ELS due to temporary separation from parents during World War II (WWII) in relation to work career. - Material and methods: The Helsinki Birth Cohort Study comprises 13,345 individuals born in Helsinki, Finland, between the years 1934–1944. From the original cohort, 1781 individuals were identified as being separated temporarily from their parents due to World War II. Information on date and type o…

MaleAgingTime FactorsWorld War IILabor forcePsychological interventionCHILDREN3124 Neurology and psychiatrySocial insuranceCohort Studies0302 clinical medicinelife cycleMedicine030212 general & internal medicinekrooniset tauditmedia_commonlabor forceRISKCareer ChoicePSYCHOPATHOLOGYta3142Middle AgedEXPERIENCESPREVALENCEPsychiatry and Mental healthClinical PsychologyEARLY-LIFE STRESS8. Economic growthWorkforceCohortFemaleHEALTHLife stresserottelu515 Psychologymedia_common.quotation_subjectLife cycleelämänkaariChronic diseaseSeparation03 medical and health sciencesMENTAL-DISORDERSADVERSITYtyöuraHumansPensionbusiness.industryDISABILITYaginglife stressstressilapsuusDisability pensionikääntyminenUnemploymentsotalapsetbusinesschronic disease030217 neurology & neurosurgeryRetirement ageStress PsychologicalDemographyJournal of psychosomatic research
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Current understandings of the trajectory and emerging correlates of cognitive impairment in bipolar disorder: An overview of evidence.

2019

Objectives Cognitive dysfunction affects a significant proportion of people with bipolar disorder (BD), but the cause, trajectory and correlates of such dysfunction remains unclear. Increased understanding of these factors is required to progress treatment development for this symptom dimension. Methods This paper provides a critical overview of the literature concerning the trajectories and emerging correlates of cognitive functioning in BD. It is a narrative review in which we provide a qualitative synthesis of current evidence concerning clinical, molecular, neural and lifestyle correlates of cognitive impairment in BD across the lifespan (in premorbid, prodromal, early onset, post-onset…

MaleBipolar DisorderMEDLINE03 medical and health sciences0302 clinical medicineCognitionmedicineHumansCognitive DysfunctionCognitive skillBipolar disorderCognitive impairmentBiological PsychiatryAgedPsychopathologyCognitionPrecision medicinemedicine.disease030227 psychiatryPsychiatry and Mental healthLifestyle factorsFemaleSymptom AssessmentPsychology030217 neurology & neurosurgeryClinical psychologyPsychopathologyBipolar disordersREFERENCES
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Classification of patients with bipolar disorder using k-means clustering.

2019

Introduction Bipolar disorder (BD) is a heterogeneous disorder needing personalized and shared decisions. We aimed to empirically develop a cluster-based classification that allocates patients according to their severity for helping clinicians in these processes. Methods Naturalistic, cross-sectional, multicenter study. We included 224 subjects with BD (DSM-IV-TR) under outpatient treatment from 4 sites in Spain. We obtained information on sociodemography, clinical course, psychopathology, cognition, functioning, vital signs, anthropometry and lab analysis. Statistical analysis: k-means clustering, comparisons of between group variables, and expert criteria. Results and discussion We obtain…

MaleBipolar DisorderPsychometricsSocial SciencesSeverity of Illness IndexMedicine and Health SciencesMedicinePsychologyCluster AnalysisPrecision MedicineCognitive ImpairmentMetabolic SyndromeMultidisciplinaryCognitive NeurologyQRCognitionMiddle AgedNeurologyMedicineFemalePsychopathologyClinical psychologyResearch ArticleAdultPsychometricsScienceCognitive NeuroscienceQuality of life (healthcare)NeuropsychologySeverity of illnessMental Health and PsychiatryHumansCognitive skillBipolar disorderNeuropsychological Testingbusiness.industryMood DisordersCognitive PsychologyConstruct validityBiology and Life SciencesReproducibility of Resultsmedicine.diseaseHealth CareCross-Sectional StudiesSpainMetabolic DisordersQuality of LifeCognitive SciencebusinessNeuroscience
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