Search results for "pump"
showing 10 items of 471 documents
Comparison of the impact of Helicobacter pylori eradication treatment with bismuth and non-bismuth quadruple regimens on the gut microbiota
2019
Background: Helicobacter pylori eradication requires a combination of antibiotics. The short and long-term effect of different H. pylori eradication regimens on the gut microbiota has received little attention. Aims: To evaluate and compare the impact of the two most frequently recommended first-line H. pylori eradication regimens — bismuth and non-bismuth quadruple regimens — on the gut microbiota. Patients and Methods: Two 14-day quadruple treatments were evaluated and compared: bismuth-based quadruple therapy (proton pump inhibitor, bismuth, tetracycline, and metronidazole) and non-bismuth quadruple “concomitant” therapy (proton pump inhibitor, amoxicillin, clarithromycin and metronidazo…
Hybridilämmitysjärjestelmän tiedonkeruu ja -analysointi omakotitalokohteelle
2013
Opinnäytetyössä suunniteltiin ja toteutettiin tiedonkeruujärjestelmä omakotitalon lämmitysjärjestelmälle, jonka muodostavat maalämpöpumppu, aurinkokeräimistö ja vesikiertoinen kamina. Lämminvesivaraajan ja tilojen lämmityksen lisäksi aurinkokeräimistö ja kamina pystyvät esilämmittämään maalämpöpumpun keruunestettä ja lämmittämään lämpöpumpun maapiiriä. Tiedonkeruun avulla saadun datan ja lähdekirjallisuuden avulla järjestelmän toimivuutta ja optimaalista käyttöä arvioitiin. Työn tarkoituksena oli myös selvittää vastasivatko aurinkokeräimelle ja kaminalle ilmoitetut hyötysuhteet mitattuja. Työn pohjaksi käytiin läpi suomalaisen pientalon lämmöntarvetta. Toteutettu tiedonkeruujärjetelmä on ka…
Uusiutuvaan energiaan perustuvan hybridilämmitysjärjestelmän toteutettavuus maatilakohteissa
2012
Tässä Pro gradu –tutkielmassa selvitettiin uusiutuviin energialähteisiin perustuvien lämmitysjärjestelmien ja myös piensähköntuotannon toimivuutta maatilakohteissa. Työssä käytiin läpi yleisimmät pientaloissa käytettävät kaupalliseen kehitysvaiheeseen päässeet teknologiat, kuten biopolttokattilat, maa- ja ilmalämpöpumput, biokaasulaitteet, pientuuliturbiinit, aurinkosähköpaneelit ja aurinkolämpökeräimet. Työn kokeellisessa osuudessa selvitettiin kolmen keskisuomalaisen maatilan nykyinen energiankulutus ja kustannukset. Kohteille suunniteltiin konseptitasolla soveltuvia lämmitysjärjestelmiä. Lisäksi selvitettiin aurinkolämpökeräimien soveltuvuutta lämpimän käyttöveden lämmitykseen ja oman sä…
The effect of off-pump coronary artery bypass on mortality after acute coronary syndrome: A meta-analysis
2012
Background Patients requiring surgical revascularisation for acute coronary syndrome (ACS) form a clinically heterogeneous group ranging from haemodynamic stability to cardiogenic shock. Whilst 'off-pump' revascularisation (OPCAB) is often considered, patient selection and operative timing remain controversial. This study aims to identify whether OPCAB may confer a mortality benefit over ONCAB in revascularisation for ACS. Secondly, we review the impact of OPCAB on completeness of revascularisation (CR) and long-term re-intervention. Methods A systematic literature review identified 9 studies (1 randomised controlled trial) of which 8 fulfilled criteria for meta-analysis. Outcomes for a tot…
Helicobacter pylori first-line and rescue treatments in patients allergic to penicillin: Experience from the European Registry on H pylori management…
2020
Background Experience in Helicobacter pylori eradication treatment of patients allergic to penicillin is very scarce. A triple combination with a PPI, clarithromycin (C), and metronidazole (M) is often prescribed as the first option, although more recently the use of a quadruple therapy with PPI, bismuth (B), tetracycline (T), and M has been recommended. Aim To evaluate the efficacy and safety of first-line and rescue treatments in patients allergic to penicillin in the "European Registry of H pylori management" (Hp-EuReg). Methods A systematic prospective registry of the clinical practice of European gastroenterologists (27 countries, 300 investigators) on the management of H pylori infect…
Is Helicobacter pylori status relevant in the management of GORD?
2000
Summary There is growing interest in the relationship between H. pylori infection and gastro-oesophageal reflux disease (GORD). However, this relationship is complex, as yet not fully elucidated, and probably based on a multiplicity of factors. The prevalence of H. pylori infection in patients with GORD is similar, more often lower than in matched controls. There is a negative correlation between H. pylori infection and the severity of GORD. There are many hypothetical mechanisms by which H. pylori infection may protect from the development of GORD. Conversely, there are many possible mechanisms by which H. pylori infection could theoretically foster the GORD. Patients after H. pylori eradi…
Analysis of the hyperpolarizing effects of forskolin in guinea-pig atrial heart muscle.
1988
The effects of forskolin on action potential configuration and on both uptake and efflux of 86Rb+ were studied in guinea-pig left atria. The action potential was prolonged by forskolin in the plateau range but shortened at the end of repolarization; maximal upstroke velocity and amplitude of slow response potentials were enhanced. In partially depolarized preparations, the resting potential was increased by forskolin; this effect was not prevented by atropine 1 μmol/1. Forskolin augmented the rate constant of 86Rb+ efflux in beating and in resting preparations. The uptake of 86Rbs+ was enhanced by forskolin in resting preparations. It is concluded that forskolin stimulates the Na+, K+ -pump…
Improving opportunities for effective management of gastro-oesophageal reflux disease
2002
The recent introduction of proton pump inhibitors has extraordinarily improved the therapeutic approach to gastro-oesophageal reflux disease. The concept of decreasing gastric acid secretion and increasing the pH in the lower oesophagus has been demonstrated to be therapeutically effective and the higher the level of pH achieved, the better the results. In spite of the evident efficacy of these molecules, there are still many patients who will continue to have symptoms despite medical treatment. Proton pump inhibitors suppress gastric acidity, but this effect shows a remarkable interindividual variation depending on different reasons. Thus, it is still possible to optimise medical therapy f…
A Nonlinear Circulatory Model for Artificial Heart Studies
1983
Animals with total artificial heart replacement (TAH) have survived for up to 9 months with manually controlled driving systems. A certain physiological control is provided by the animals intact peripheral regulation resulting in pathological venous hemodynamics, expressing the needs for a technical automatic control system, replacing the natural sympathetic stimulation and Starlings Law of the heart. A nonlinear dynamic mathematical model of the human cardiovascular system (CVSM) containing the systemic and pulmonary components was outlined and verified, which is employable to analyse the hemodynamic behaviour under normal and abnormal states. By modifying this model, assuming that cardiac…
2020
There is evidence that intake of proton pump inhibitors (PPI) increases the risk for spontaneous bacterial peritonitis (SBP) in patients with liver cirrhosis. However, data regarding the impact of PPI intake on occurrence of infections other than SBP are still lacking.We hypothesized that PPI use is associated with a higher rate of infections other than SBP in patients with liver cirrhosis.The current case-control study sample included patients with liver cirrhosis from the Disease Analyzer database (IQVIA), which compiles data such as risk factors, drug prescriptions and diagnoses obtained from general practitioners and specialists in Germany. In total, 2,823 patients with infections were …