Search results for "race."
showing 10 items of 4442 documents
MTOR inhibitor-based combination therapies for pancreatic cancer
2018
Background: Although the mechanistic target of rapamycin (MTOR) kinase, included in the mTORC1 and mTORC2 signalling hubs, has been demonstrated to be active in a significant fraction of patients with pancreatic ductal adenocarcinoma (PDAC), the value of the kinase as a therapeutic target needs further clarification. Methods: We used Mtor floxed mice to analyse the function of the kinase in context of the pancreas at the genetic level. Using a dual-recombinase system, which is based on the flippase-FRT (Flp-FRT) and Cre-loxP recombination technologies, we generated a novel cellular model, allowing the genetic analysis of MTOR functions in tumour maintenance. Cross-species validation and pha…
Microalgae-bacteria consortia for urban wastewater treatment
2021
Los consorcios de microalgas y bacterias surgen como una opción idónea en el marco de las tecnologías sostenibles para el tratamiento de aguas residuales. Los mecanismos de eliminación de contaminantes son el resultado de interacciones ecológicas directas y/o indirectas entre las microalgas y las bacterias autóctonas de las aguas residuales. Para diseñar sistemas eficaces que incorporen consorcios de microalgas y bacterias es necesario comprender las interacciones ecológicas entre ambas comunidades dentro de los procesos de tratamiento de aguas residuales. El objetivo principal de este trabajo de investigación es, por tanto, estudiar y explorar las interacciones ecológicas para mejorar el t…
Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise
2020
Physical exercise induces acute physiological changes leading to enhanced tissue cross-talk and a liberation of extracellular vesicles (EVs) into the circulation. EVs are cell-derived membranous entities which carry bioactive material, such as proteins and RNA species, and are important mediators of cell-cell-communication. Different types of physical exercise interventions trigger the release of diverse EV subpopulations, which are hypothesized to be involved in physiological adaptation processes leading to health benefits and longevity. Large EVs (“microvesicles” and “microparticles”) are studied frequently in the context of physical exercise using straight forward flow cytometry approach…
Productive, Commercial and Qualitative characterization of tomato sicilian landraces
2010
Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Rel…
2020
This research aimed to evaluate the effects of the inclusion of honey bee pollen (HBP) in meagre (Argyrosoumus regius) juveniles&rsquo
Dividing Responsibility for Care : Tracing the Ethics of Care in Local Care Strategies
2020
This article analyses local care policies through the lens of the feminist ethics of care. The focus is on the normative understandings regarding care that emerge in local care strategy documents and how these understandings relate with the concept of ‘responsibility’. In this article, strategies published by the municipality of Jyväskylä, Finland, between the years 2008 and 2016, are analysed using Trace analysis. The research questions are: How is the division of responsibility regarding care among different actors constructed in the strategies? How do the roles assigned to these different actors accord with the principles of ethics of care? The findings show that the documents emphasise …
The effects of heart rate variability and cardiac cycle time on learning in trace eye-blink conditioning
2017
Ärsykkeen sydämen sykkeeseen ajastamisella on huomattu olevan yhteyttä sensoriseen havainnointiin ja korkeampaan kognitiiviseen prosessointiin, kun sykevälivaihtelu (HRV)puolestaan on yhdistetty tarkkaavaisuuteen. Tässä tutkimuksessa tarkasteltiin sykevälivaihtelun sekä ärsykkeen sydämen sykkeeseen ajastamisen yhteyksiä oppimiseen. Koehenkilöt osallistuivat silmäniskuehdollistumiskokeeseen, missä ärsykkeet oli ajastettu joko sydämen sykkeen systoliseen tai diastoliseen vaiheeseen. HRV:n ja EEG:n mittaaminen aloitettiin viisi minuuttia ennen kokeen alkua ja sitä jatkettiin viisi minuuttia kokeen loppumisen jälkeen. Tutkimuksessa tarkasteltiin kuutta HRV-muuttujaa: sykevälin keskiarvo (MRR), …
The cycle of major and trace elements in a volcanic environment
2010
Atmospheric Deposition Of Volcanogenic Major And Trace Elements On Mt. Etna (Italy)
2009
There are a variety of natural and anthropogenic sources of trace elements into the environment, and human activity has drastically changed the biogeochemical cycles and balance of several elements. In the last twenty years many efforts have been spent by the scientific community to better outline the levels of pollutants in the environment on a long-term basis, and to evaluate global large-scale changes. It is generally accepted that volcanic emissions are an important source of gases and particles to the atmosphere, contributing significantly to the natural geochemical cycles of all elements (Nriagu, 1989; Hinkley et al., 1999; Oppenheimer, 2003). Many studies have been carried out on the…
Trace elements in thermomineral waters in Greece
2020
Trace elements have a fundamental role in natural and anthropogenic systems. In waters, they present a great variability of concentrations that mostly depends on the degree of gas-water-rock interactions and geochemical conditions such as pH, temperature, redox and/or exchange reactions, etc. Even though, they are present in very low contents in host-rocks, elevated concentrations in ground or surface waters may have a hazardous impact on human health and thus, it is important to both quantify and understand their behavior in natural systems. Here we present the results of about 300 cold and thermal mineral waters collected along the entire Hellenic territory. Physicochemical parameters (te…