Search results for "radionuclide"

showing 10 items of 196 documents

2017

In the context of radiopharmacy and molecular imaging, the concept of theranostics entails a therapy-accompanying diagnosis with the aim of a patient-specific treatment. Using the adequate diagnostic radiopharmaceutical, the disease and the state of the disease are verified for an individual patient. The other way around, it verifies that the radiopharmaceutical in hand represents a target-specific and selective molecule: the “best one” for that individual patient. Transforming diagnostic imaging into quantitative dosimetric information, the optimum radioactivity (expressed in maximum radiation dose to the target tissue and tolerable dose to healthy organs) of the adequate radiotherapeutica…

Radionuclidemedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentPharmaceutical ScienceNuclear dataContext (language use)010403 inorganic & nuclear chemistry01 natural sciences030218 nuclear medicine & medical imaging0104 chemical sciencesRadiation therapy03 medical and health sciences0302 clinical medicinePositron emission tomographyDrug DiscoverymedicineMedical imagingMolecular MedicineDosimetryMolecular imagingNuclear medicinebusinessPharmaceuticals
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Broad beam transmission curves for new radionuclides in brachytherapy

2007

Radionuclidemedicine.medical_specialtyOncologybusiness.industryNuclear engineeringmedicine.medical_treatmentBrachytherapyMedicineRadiology Nuclear Medicine and imagingMedical physicsBeam transmissionbusinessBrachytherapy
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68 Ga‐Labelled Tropane Analogues for the Visualization of the Dopaminergic System

2020

Abstract The development of radiometal‐labelled pharmaceuticals for neuroimaging could offer great potential due to easier handling during labelling and availability through radionuclide generator systems. Nonetheless, to date, no such tracers are available for positron emission tomography, primarily owing to the challenge of crossing the blood–brain barrier (BBB) and loss of affinity through chelator attachment. We have prepared a variety of 68Ga‐labelled phenyltropanes showing that, through a simple hydrocarbon‐linker, it is possible to introduce a chelator onto the lead structure while maintaining its high affinity for hDAT (human dopamine transporter) and simultaneously achieving adequa…

Rat modeltropane01 natural sciencesBiochemistrychemistry.chemical_compoundgallium-68Drug DiscoverylipophilicitymedicineGeneral Pharmacology Toxicology and PharmaceuticsradiopharmaceuticalsDopamine transporterPharmacologyFull Paperbiologymedicine.diagnostic_test010405 organic chemistryChemistryOrganic ChemistryDopaminergicdopamine transportersTropaneFull Papers0104 chemical sciencesimaging agents010404 medicinal & biomolecular chemistryPositron emission tomographyLipophilicityLead structurebiology.proteinBiophysicsMolecular MedicineRadionuclide GeneratorChemMedChem
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Submarine groundwater discharge investigations in Sicilian and Brazilian coastal waters using an underwater gamma-ray spectrometer

2006

Abstract Submarine groundwater discharge (SGD) in coastal zones was monitored using in situ underwater gamma-ray spectrometry of radon decay products ( 214 Bi). Several sites were visited during the IAEA'2002 expedition to south-eastern Sicily, where SGD variations were observed in the Donnalucata boat basin. The continuous monitoring carried out for 3 days at the site closest to the coast revealed an anticorrelation dependence of 222 Rn concentration with tide and salinity. The 222 Rn activity concentrations in seawater varied from 2.3 kBq m −3 (during high tides) to 4.8 kBq m −3 (during low tides). In situ gamma-ray spectrometric measurements were also carried out during the IAEA–UNESCO'2…

SalinityHydrologyRadionuclideOceanographyMediterranean seaSeawaterBaySubmarine groundwater dischargeGeologyGroundwaterSea level
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Fission Product Activity Measurements in Air Particulate Filters Collected after Fukushima Accident at Palermo, Italy

2012

In the framework of routine operation of AGN-201 COSTANZA Nuclear research reactor, measurements of radionuclide air concentration are periodically performed by filtering an high volume of air through paper filters and by using HPGe gamma-ray spectrometry. After Fukushima accident, a series of samplings was carried out with a daily frequency so to detect the possible arrival of air radioactive contamination and to follow its evolution. Particulate collection was performed by suction of atmospheric air through 45cm × 45cm Sofiltra-Poelman HYN-75 (Bleu type) cellulose filter paper using a high-volume air sampler located on the roof of our department 20 m above ground-level. The sampling time …

Settore ING-IND/20 - Misure E Strumentazione NucleariAir Particulate Fukushima accident radionuclide concentration.
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[Physiopathological significance of renal blood flow reduction in patients with essential arterial hypertension].

1990

a group of 120 patients suffering from E.A.H. divided into three age Plasma renal flow was reduced on average in all three groups. It is t this fact could support the hypothesis that the change in renal per y a pathogenic role in E.A.H. ss F1/hlp F2/que F3/ext F4/can F5/nxt F6/ins F7/up F8/dwn F9/fin

Settore MED/14 - NefrologiaAdultMaleSettore MED/09 - Medicina InternaAge FactorsMiddle AgedKidneySettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheSettore MED/11 - Malattie Dell'Apparato CardiovascolareRenal CirculationAdult Age Factors Female Humans Hypertension/etiology Hypertension/physiopathology* Kidney/radionuclide imaging Male Middle Aged Renal Circulation*HypertensionHumansFemaleRadionuclide ImagingMinerva medica
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Observation of a $\gamma$-decaying millisecond isomeric state in $^{128}$Cd$_{80}$

2017

A. Jungclaus et al. -- 6 pags., 5 figs., 2 tabs. -- Open Access funded by Creative Commons Atribution Licence 4.0

Shell model calculationNuclear and High Energy PhysicsFissionSHELL modelNuclear TheoryShell model calculationsTransition strengths[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciences7. Clean energy0103 physical sciencesmedicineddc:530010306 general physicsNuclear ExperimentPhysicsMillisecondRadionuclideIsomeric decay010308 nuclear & particles physicsProjectileParity (physics)lcsh:QC1-999medicine.anatomical_structureIsomeric decaysPhysics::Accelerator PhysicsTransition strengthAtomic physicsNucleuslcsh:Physics
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Effect of soil management on its radioisotopic composition

2015

Radioactive isotopes, both natural and artificial, present in the environment may be convenient indicators that can be used to study a number of physical and chemical processes and transport of pollutants in the ecosystem.The main aim of the study was to evaluate the impact of the type of soil use on the radioisotopic composition in its surface layers. The radioisotopic compositions of surface soil samples collected in the area of a cement plant abandoned for over 20 years and in the area of the nearby allotments were examined and compared. Calculations were performed using methods designed to study compositional variables.The results confirmed a significant impact of usage on the radioisot…

Soil managementPollutantRadionuclideIsotopeSoil testChemistryEnvironmental chemistrySoil horizonComposition (visual arts)Geology, Geophysics & Environment
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Robustness of PET Radiomics Features: Impact of Co-Registration with MRI

2021

Radiomics holds great promise in the field of cancer management. However, the clinical application of radiomics has been hampered by uncertainty about the robustness of the features extracted from the images. Previous studies have reported that radiomics features are sensitive to changes in voxel size resampling and interpolation, image perturbation, or slice thickness. This study aims to observe the variability of positron emission tomography (PET) radiomics features under the impact of co-registration with magnetic resonance imaging (MRI) using the difference percentage coefficient, and the Spearman’s correlation coefficient for three groups of images: (i) original PET, (ii) PET after co-…

TechnologyTomografía de emisión de positronesNeoplasias encefálicasCorrelation coefficientImagen por resonancia magnética:Phenomena and Processes::Mathematical Concepts::Probability::Uncertainty [Medical Subject Headings]QH301-705.5Computer scienceQC1-999:Diseases::Neoplasms::Neoplasms by Site::Nervous System Neoplasms::Central Nervous System Neoplasms::Brain Neoplasms [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging [Medical Subject Headings]Co registrationFluid-attenuated inversion recovery:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Magnetic resonance imagingRadiomicsRobustness (computer science):Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques Radioisotope::Radionuclide Imaging::Tomography Emission-Computed::Positron-Emission Tomography [Medical Subject Headings]Resamplingradiomics feature robustness; imaging quantification; [11C]-methionine positron emission tomography; PET/MRI co-registration Appl.medicineGeneral Materials ScienceBiology (General)QD1-999InstrumentationSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniFluid Flow and Transfer Processesmedicine.diagnostic_testbusiness.industryTPhysicsProcess Chemistry and TechnologyRadiomics feature robustnessGeneral EngineeringPET/MRI co-registrationMagnetic resonance imagingPattern recognitionEngineering (General). Civil engineering (General)Imaging quantificationComputer Science ApplicationsChemistry:Chemicals and Drugs::Amino Acids Peptides and Proteins::Amino Acids::Amino Acids Essential::Methionine [Medical Subject Headings]Positron emission tomography[11C]-methionine positron emission tomography:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings]Artificial intelligenceTA1-2040businessApplied Sciences
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Impacts of oak deforestation and rainfed cultivation on soil redistribution processes across hillslopes using 137Cs techniques

2021

Abstract Background As one of the main components of land-use change, deforestation is considered the greatest threat to global environmental diversity with possible irreversible environmental consequences. Specifically, one example could be the impacts of land-use changes from oak forests into agricultural ecosystems, which may have detrimental impacts on soil mobilization across hillslopes. However, to date, scarce studies are assessing these impacts at different slope positions and soil depths, shedding light on key geomorphological processes. Methods In this research, the Caesium-137 (137Cs) technique was applied to evaluate soil redistribution and soil erosion rates due to the effects …

Topographical changes010504 meteorology & atmospheric sciencesSoil testLand managementLand-use change01 natural sciencesSoil redistributionDeforestationEcosystemDeforestationTransectEcology Evolution Behavior and SystematicsQH540-549.50105 earth and related environmental sciencesNature and Landscape ConservationHydrologygeographygeography.geographical_feature_categoryEcologyLandformForestry04 agricultural and veterinary sciencesSoil water040103 agronomy & agricultureErosionRadionuclide0401 agriculture forestry and fisheriesEnvironmental scienceRainfed farmingForest Ecosystems
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