Search results for "randomized-trials"

showing 3 items of 3 documents

Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA.IT study

2017

Background: The role of polyphenol intake on cardiovascular risk factors is little explored, particularly in people with diabetes. Aim: To evaluate the association between the intake of total polyphenols and polyphenol classes with the major cardiovascular risk factors in a population with type 2 diabetes. Methods: Dietary habits were investigated in 2573 males and females participants of the TOSCA.IT study. The European Prospective Investigation on Cancer and Nutrition (EPIC) questionnaire was used to assess dietary habits. In all participants, among others, we assessed anthropometry, plasma lipids, blood pressure, C-reactive protein and HbA1c following a standard protocol. The USDA and Ph…

Male0301 basic medicinePhysiologyType 2 diabetes030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineSettore MED/13 - Endocrinologiachemistry.chemical_compound0302 clinical medicineDietary polyphenolsFlavonoidsPhenolic acidsCardiovascular riskType 2 diabetesLOW-GRADE INFLAMMATIONBLOOD-PRESSUREDIETARY POLYPHENOLSDARK CHOCOLATEINSULIN SENSITIVITYRANDOMIZED-TRIALSDISEASEMETAANALYSISMETABOLISMCHOLESTEROLRisk FactorsSurveys and QuestionnairesHydroxybenzoatesProspective StudiesFood scienceCardiovascular risk; Dietary polyphenols; Flavonoids; Phenolic acids; Type 2 diabeteseducation.field_of_studyPhenolic acidNutrition and Dieteticsbiologyfood and beveragesType 2 diabetesDietary polyphenolMiddle AgedDietary polyphenols; Flavonoids; Phenolic acids; Cardiovascular risk; Type 2 diabetesEuropean Prospective Investigation into Cancer and NutritionDietary polyphenolsCardiovascular DiseasesFemalePhenolic acidsPopulationCardiovascular risk Dietary polyphenols Flavonoids Phenolic acids Type 2 diabetes03 medical and health sciencesDiabetes mellitusmedicineHumanseducationTriglyceridesAgedFlavonoids030109 nutrition & dieteticsDose-Response Relationship Drugbusiness.industryCholesterol HDLC-reactive proteinPolyphenolsCholesterol LDLAnthropometrymedicine.diseaseCardiovascular riskCardiovascular risk; Dietary polyphenols; Flavonoids; Phenolic acids; Type 2 diabetes; Nutrition and Dietetics; Critical Care and Intensive Care MedicineDietCross-Sectional StudiesNutrition AssessmentDiabetes Mellitus Type 2chemistryFlavonoidbiology.proteinGlycated hemoglobinbusinessBody mass index
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Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysi…

2022

ABSTRACTIntroductionBehavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted an increase in very early childhood obesity prevention trials worldwide. Combining the individual participant data (IPD) from these trials will enhance statistical power to determine overall effectiveness and enable examination of intervention-covariate interactions. We present a protocol for a systematic review with IPD meta-analysis to evaluate the effectiveness of obesity prevention interventions commen…

GerontologyobesityPediatric ObesityMEDLINEPsychological interventionCINAHLPsycINFOpreventive medicineChildhood obesityBody Mass IndexpaediatricsMeta-Analysis as TopicBehavior TherapyMedicine and Health SciencesmedicineHumansEarly childhoodProspective Studies1506ChildExerciseASSOCIATIONSResearch ethicsOVERWEIGHTbusiness.industrypublic healthRInfantGeneral Medicinemedicine.diseaseRANDOMIZED-TRIALSBODY-MASS INDEX000 DAYSPHYSICAL-ACTIVITYMeta-analysisChild PreschoolRISK-FACTORS1114 Paediatrics and Reproductive MedicineMedicineWEIGHTHEALTHTRAJECTORIESbusiness1ST 1Developmental Psychopathology1719community child healthSystematic Reviews as Topic
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Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospect…

2014

Summary Background Body-mass index (BMI) and diabetes have increased worldwide, whereas global average blood pressure and cholesterol have decreased or remained unchanged in the past three decades. We quantified how much of the effects of BMI on coronary heart disease and stroke are mediated through blood pressure, cholesterol, and glucose, and how much is independent of these factors. Methods We pooled data from 97 prospective cohort studies that collectively enrolled 1·8 million participants between 1948 and 2005, and that included 57 161 coronary heart disease and 31 093 stroke events. For each cohort we excluded participants who were younger than 18 years, had a BMI of lower than 20 kg/…

medicine.medical_specialtySettore MED/09 - Medicina InternaNutrition and Diseasenoncommunicable diseasesbariatric surgeryscientific statementcardiovascular-diseaseCoronary DiseaseOverweightsystematic analysisBody Mass Indexblood-pressureInternal medicineDiabetes mellitusVoeding en ZiektemedicineHumansProspective cohort studyrisk-factorsStrokeVLAGHuman Nutrition & HealthGlobal NutritionWereldvoedingFramingham Risk Scorebusiness.industryHumane Voeding & GezondheidArticlesGeneral MedicineOverweightmedicine.diseaseObesityStrokeBlood pressurerandomized-trialsPhysical therapyCardiologyall-cause mortalitymedicine.symptombusinessBody mass indexbody-mass index obesity coronary heart disease strokeweight-loss
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