Search results for "range"

A Nomogram-Based Prognostic Model for Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib: A Multicenter Study

2021

Simple Summary Accurate prognostic systems capable of predicting the survival of patients with advanced hepatocellular carcinoma undergoing Sorafenib therapy are still lacking. The search for the ideal predictive tool for survival and drug response is justified by the recent availability of several other drugs effective for these patients, licensed as first- and second-line treatment, other than reducing adverse events and costs. In this study, we aimed to identify simple demographic and clinical parameters able to predict survival and Sorafenib response in a large multicenter cohort. In this study, we showed that patient’s general status, liver function and damage laboratory parameters and…

Rotational diffusion of colloid spheres in concentrated suspensions studied by deuteron NMR

1997

We present a study of the application of deuteron-nuclear magnetic resonance spectroscopy (NMR) to the investigation of the rotational diffusion of spherical colloidal particles. We performed NMR pulse experiments on colloidal suspensions of polystyrene latex spheres in water-glycerol mixtures in a wide range of particle volume fractions \ensuremath{\varphi} from the dilute suspension up to \ensuremath{\varphi}=0.504. We have analyzed the stimulated echo NMR signal in the time domain. The full shape of the orientational correlation function deviates from an exponential behavior in the whole \ensuremath{\varphi} range examined. We evaluate the rotational diffusion coefficient and calculate i…

Factored arrangements of hyperplanes

1994

On bijections vs. unary functions

1996

A set of finite structures is in Binary NP if it can be characterized by existential second order formulas in which second order quantification is over relations of arity 2. In [DLS95] subclasses of Binary NP were considered, in which the second order quantifiers range only over certain classes of relations. It was shown that many of these subclasses coincide and that all of them can be ordered in a three-level linear hierarchy, the levels of which are represented by bijections, successor relations and unary functions respectively.

Nearly tight bounds on the learnability of evolution

2002

Evolution is often modeled as a stochastic process which modifies DNA. One of the most popular and successful such processes are the Cavender-Farris (CF) trees, which are represented as edge weighted trees. The Phylogeny Construction Problem is that of, given /spl kappa/ samples drawn from a CF tree, output a CF tree which is close to the original. Each CF tree naturally defines a random variable, and the gold standard for reconstructing such trees is the maximum likelihood estimator of this variable. This approach is notoriously computationally expensive. We show that a very simple algorithm, which is a variant on one of the most popular algorithms used by practitioners, converges on the t…

The Adequate Stimulus

2008

The term adequate stimulus describes that class of environmental phenomena that requires the least amount of energy to elicit a percept mediated by a particular sensory system, implying that the receptive organs of that sensory system are specialized to detect those phenomena. It was difficult to transfer this concept to the perception of pain and to the nociceptive system. Many different stimuli may cause pain (pin prick, burn injury, freeze injury, inflammation, etc.), none of which needs particularly low amounts of energy. The common denominator of those stimuli is that they threaten to cause tissue damage (in Greek: νoξη Noxe). Hence the adequate stimulus to elicit pain is traditionally…

Recognition of familiarity on the basis of howls: a playback experiment in a captive group of wolves

2015

Playback experiments were conducted with a pack of captive Iberian wolves. We used a habituation–discrimination paradigm to test wolves’ ability to discriminate howls based on: (1) artificial manipulation of acoustic parameters of howls and (2) the identity of howling individuals. Manipulations in fundamental frequency and frequency modulation within the natural range of intra-individual howl variation did not elicit dishabituation, while manipulation of modulation pattern did produce dishabituation. With respect to identity, across trials wolves habituated to unfamiliar howls by a familiar wolf (i.e., no direct contact, but previous exposure to howls by this wolf), but not to unfamiliar ho…

A Lebesgue-type decomposition for non-positive sesquilinear forms

2018

A Lebesgue-type decomposition of a (non necessarily non-negative) sesquilinear form with respect to a non-negative one is studied. This decomposition consists of a sum of three parts: two are dominated by an absolutely continuous form and a singular non-negative one, respectively, and the latter is majorized by the product of an absolutely continuous and a singular non-negative forms. The Lebesgue decomposition of a complex measure is given as application.

Minimality as vacuous distinctness: Evidence from cross-linguistic sentence comprehension

2009

Abstract Psycholinguistic theorising has long been shaped by the assumption that the processing system endeavours to minimise structures/relations during online comprehension. Within the scope of a recent cross-linguistic, neurocognitive model of sentence comprehension (Bornkessel and Schlesewsky, 2006), we also proposed that the assumption of a very general ‘Minimality’ principle can account for a variety of psycholinguistic findings from a range of languages. In the present paper, we review empirical evidence for this notion of Minimality, before going on to discuss its limitations. On the basis of this discussion, we propose that, rather than constituting an independent processing princi…

Using the visualization tool SimReal to orchestrate mathematical teaching for engineering students

2018

Visualization tools provide a potentially powerful support for the learning of abstract mathematical topics in engineering courses. SimReal is a visualization tool for teaching mathematics for a wide range of engineering topics. It provides video lessons, interactive simulations and animations to enhance comprehension and engagement in abstract mathematics subjects. The aim of this paper is to explore the role of SimReal to orchestrate mathematical teaching for engineering students. It uses the framework of instrumental orchestration to configure and exploit various artefacts with the intention of performing a didactical purpose.