Search results for "rare"

showing 10 items of 2778 documents

The Small Size and Superficial Location Suggest That Laparoscopic Partial Nephrectomy Is the First Choice for the Treatment of Juxtaglomerular Cell T…

2021

BackgroundJuxtaglomerular cell tumor (JGCT) is a very rare disease, and surgical resection is the only possible way to cure this tumor. Open nephrectomy and partial nephrectomy have been reported to manage JGCTs with excellent results in the previous reviews. Laparoscopic surgery has been popularized in recent years, while critical issues associated with laparoscopic surgical management have been seldom reported. We summarized the JGCTs in our center to discover the optimal surgical management and its anatomic foundation.MethodsIn this retrospective study, we enrolled a total of 14 JGCT patients. All patients received surgeries and were followed up for up to 11 years. We mainly summarized t…

AdenomaAdultMaleLaparoscopic surgerymedicine.medical_specialtyAdolescentEndocrinology Diabetes and Metabolismmedicine.medical_treatmentsuperficial location030204 cardiovascular system & hematologyNephrectomyPlasma renin activityDiseases of the endocrine glands. Clinical endocrinologysmall sizeYoung Adult03 medical and health sciencesEndocrinologyPostoperative Complications0302 clinical medicinemedicineHumansCarcinoma Renal CellOriginal ResearchAgedRetrospective Studieslaparoscopic partial nephrectomybusiness.industryRetrospective cohort studyjuxtaglomerular cell tumorsMiddle AgedRC648-665medicine.diseaseMagnetic Resonance ImagingKidney NeoplasmsHypokalemiaNephrectomySurgeryBlood pressure030220 oncology & carcinogenesisFemaleLaparoscopymedicine.symptombusinessJuxtaglomerular cell tumorlaparoscopic ultrasoundRare diseaseFrontiers in Endocrinology
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CT and MR Imaging Evaluation of Hepatic Adenoma

2006

Hepatic adenoma is a rare benign epithelial tumor that is usually encountered in young women who use oral contraceptives. It is clinically significant because of the risk of hemorrhage and of its low-grade malignancy potential. Adenomas usually are mildly hypervascular at contrast-enhanced CT and MR imaging, and heterogeneous due to the presence of hemorrhage, necrosis, calcifications and fat. The objective of our study was to illustrate the CT and MR imaging findings of hepatic adenoma.

AdenomaAdultmedicine.medical_specialtyNecrosisAdenomaComputed tomographyMalignancyDiagnosis DifferentialRare DiseasesmedicineHumansRadiology Nuclear Medicine and imagingBenign epithelial tumormedicine.diagnostic_testbusiness.industryLiver NeoplasmsMagnetic resonance imagingMiddle Agedmedicine.diseaseMagnetic Resonance ImagingMr imagingstomatognathic diseasesLiverFocal Nodular HyperplasiaFemaleRadiologymedicine.symptomTomography X-Ray ComputedbusinessLiver pathologyJournal of Computer Assisted Tomography
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Coordination properties of adenosine-5'-monophosphate and related ligands towards Me2Sn(IV)2+ in aqueous solution.

2002

Abstract The coordination of Me 2 Sn(IV) 2+ to adenosine-5′-monophosphate (AMP) and the related compounds d -ribose-5-phosphate (R5P), d -glucose-1-phosphate (G1P) and d -glucose-6-phosphate (G6P) in aqueous solution was investigated by means of potentiometric titration, and 1 H-, 31 P-NMR and Mossbauer spectroscopic methods in the pH range 2–11 ( I =0.1 M NaClO 4 , 298 K). The complex of AMP and Me 2 Sn(IV) 2+ precipitated at low pH was characterised by elemental analysis, FT-IR and Mossbauer spectroscopic methods. From a comparison of the p K values obtained in the presence and absence of metal ion and the stability constants for the different systems, the coordination of {N} is excluded,…

Adenosine monophosphateDenticityMagnetic Resonance SpectroscopyPotentiometric titrationInorganic chemistryMolecular Sequence DataLigandsBiochemistryInorganic ChemistryMetalchemistry.chemical_compoundSpectroscopy MossbauerDeprotonationMössbauer spectroscopySpectroscopy Fourier Transform InfraredOrganotin CompoundsAqueous solutionMolecular StructureHydrolysisGlucosephosphatesDNAHydrogen-Ion ConcentrationPhosphateAdenosine MonophosphateSolutionsCrystallographychemistryvisual_artvisual_art.visual_art_mediumPotentiometryThermodynamicsJournal of inorganic biochemistry
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Aceruloplasminaemia: a family with a novel mutation and long-term therapy with deferasirox.

2014

Ceruloplasmin is a member of the multicopper oxidase family that plays a major role in the transport of iron in the body. Aceruloplasminaemia (ACP) is a rare disease and is clinically identified by iron overload in liver, pancreas, brain, and other organs, and by microcytic anaemia. So far, the iron chelator deferasirox was given for therapy only up to 6 months due to side effects. Here, we describe a novel mutation leading to ACP and report for the first time a long-term therapy, that is, 2 years with deferasirox. ACP was diagnosed in 3 siblings using clinical and biochemical characteristics, HFE and ceruloplasmin mutational analysis, liver biopsy, brain-, liver-, and heart-MRI. For iron d…

AdultBlood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and MetabolismIronClinical BiochemistryCarbohydrate metabolismBiochemistryBenzoatesEndocrinologyInsulin resistanceHepcidinInternal medicineGermanyMedicineHumansChelating Agentsbiologymedicine.diagnostic_testbusiness.industryBiochemistry (medical)DeferasiroxCeruloplasminNeurodegenerative DiseasesGeneral MedicineTriazolesmedicine.diseaseIron Metabolism DisordersMagnetic Resonance ImagingPedigreeDeferasiroxEndocrinologymedicine.anatomical_structureTreatment OutcomeLiverLiver biopsyMutationbiology.proteinFemaleChromosomes Human Pair 3businessCeruloplasminPancreasmedicine.drugRare diseaseHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
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Unravelling the heterogeneity of soft tissue and bone sarcoma patients’ health-related quality of life: a systematic literature review with focus on …

2020

Contains fulltext : 229532.pdf (Publisher’s version ) (Open Access) Patients with sarcoma experience many physical and psychological symptoms, adversely affecting their health-related quality of life (HRQoL). HRQoL assessment is challenging due to the diversity of the disease. This review aims to unravel the heterogeneity of HRQoL of patients with sarcoma with regard to tumour location and to summarise the used measures in research. English-language literature from four databases published between January 2000 and April 2019 was reviewed. Studies that described adult sarcoma HRQoL outcomes were included and classified according to primary sarcoma location. Eighty-seven articles met the incl…

AdultCancer Researchmedicine.medical_specialtyConstitutional symptomsPopulationbone sarcomaSoft Tissue NeoplasmsReviewBone Sarcomalcsh:RC254-282Quality of lifeInternal medicineSurveys and QuestionnairesMedicineHumans1506educationeducation.field_of_studyOsteosarcomabusiness.industrySoft tissue sarcomaSarcomamedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogenshumanitieshealth-related quality of lifeSystematic reviewOncologypatient-reported outcomessoft tissue sarcomaQuality of LifeSarcomabusinessPsychosocialRare cancers Radboud Institute for Health Sciences [Radboudumc 9]ESMO Open
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Inflammatory Pseudotumor of Mediastinum Treated with Tomotherapy and Monitored with FDG-PET/CT: Case Report and Literature Review

2010

Mediastinal inflammatory pseudotumor is a rare disease with reactive pseudoneoplastic features and a proven capacity for local invasion. The radiographic appearance of inflammatory pseudotumor is quite non-specific and the definitive diagnosis is based on the histological evaluation of tissue specimens. Resection of the lesion is the treatment of choice. However, nonsurgical treatments such as radiotherapy and steroids have been employed in the setting of incomplete surgical resection, tumor recurrence, and patients being unfit for surgery. The case described here is being reported because of the rare mediastinal location and atypical treatment approach including salvage irradiation and mon…

AdultCancer Researchmedicine.medical_specialtyPET/CTRadiographymedicine.medical_treatmenttomotherapyAdult; Granuloma Plasma Cell; Humans; Mediastinal Neoplasms; Positron-Emission Tomography; Tomography X-Ray Computed; Fluorodeoxyglucose F18; RadiopharmaceuticalsMediastinal NeoplasmsGranuloma Plasma CellTomotherapy030218 nuclear medicine & medical imagingInflammatory pseudotumorLesion03 medical and health sciences0302 clinical medicineFluorodeoxyglucose F18HumansMedicineTomographyPET-CTGranulomabusiness.industryMediastinumGeneral MedicinemediastinumX-Ray ComputedRadiation therapymedicine.anatomical_structureOncologyPositron-Emission TomographyPlasma CellInflammatory pseudotumorRadiologyRadiopharmaceuticalsmedicine.symptomTomography X-Ray Computedbusiness030217 neurology & neurosurgeryRare diseaseTumori Journal
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Quality-of-Life Priorities in Patients with Thyroid Cancer : a Multinational European Organisation for Research and Treatment of Cancer Phase I Study

2016

Item does not contain fulltext BACKGROUND: The objectives of this study were to determine quality of life (QoL) issues that are relevant to thyroid cancer patients cross-culturally, and to identify those with highest relevance to them in addition to the more general issues covered by the core European Organisation for Research and Treatment of Cancer QoL questionnaire (EORTC QLQ-C30). METHODS: A systematic literature search provided a list of potentially relevant QoL issues to supplement the core questionnaire EORTC QLQ-C30, which is widely used in research and in care and addresses QoL issues relevant to all groups of cancer patients. A panel of experts revised this list, and thyroid cance…

AdultCross-Cultural ComparisonMalemedicine.medical_specialtyPathologyInternationalityEndocrinology Diabetes and MetabolismAlternative medicine030209 endocrinology & metabolism03 medical and health sciences0302 clinical medicineEndocrinologyQuality of lifeAdenocarcinoma FollicularMedicineHumansIn patientThyroid NeoplasmsVoluntary Health AgenciesThyroid cancerFatigueAgedNeoplasm StagingAged 80 and overbusiness.industryCancerRehabilitation VocationalMiddle Agedmedicine.diseaseCross-cultural studiesCombined Modality TherapyCarcinoma PapillaryhumanitiesPhase i studyCarcinoma NeuroendocrineEuropeMultinational corporationThyroid Cancer Papillary030220 oncology & carcinogenesisFamily medicineCarcinoma MedullaryQuality of LifeFemaleSelf ReportbusinessRare cancers Radboud Institute for Health Sciences [Radboudumc 9]
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A very rare cause of retroperitoneal bleeding in young patients: do not forget the occurrence of a ruptured left gastroepiploic artery aneurysm!

2019

Visceral artery aneurysms represent a very rare condition. The affected patients usually present as emergency secondary to the sudden rupture of the aneurysm or as an incidental finding on imaging. In this setting, gastric and gastroepiploic aneurysms account for only about 4% of all the splancnic aneurysms. Since ruptured visceral aneurysms present a high mortality, a prompt and adequate (surgical or radiological interventional) treatment is mandatory. Due to the difficulty in achieving an adequate transcatheter access in some cases the emergency laparotomy may represent the only chance for the recover of the affected patients. We report two cases of ruptured left gastroepiploic aneurysms …

AdultEmergencieMaleLaparotomyRupture SpontaneousRupture SpontaneouHemorrhageAneurysm RupturedYoung AdultSettore MED/18 - Chirurgia GeneraleRare DiseasesRare DiseaseHumansLaparoscopyRetroperitoneal SpaceEmergenciesGastroepiploic ArteryHuman
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Systematic review of the health-related quality of life issues facing adolescents and young adults with cancer

2017

Contains fulltext : 174665.pdf (Publisher’s version ) (Open Access) PURPOSE: For adolescents and young adults (AYAs), the impact of a cancer diagnosis and subsequent treatment is likely to be distinct from other age groups given the unique and complex psychosocial challenges of this developmental phase. In this review of the literature, we report the health-related quality of life (HRQoL) issues experienced by AYAs diagnosed with cancer and undergoing treatment. METHODS: MEDLINE, EMBASE, CINAHL, PsychINFO and the Cochrane Library Databases were searched for publications reporting HRQoL of AYAs. Issues generated from interviews with AYAs or from responses to patient reported outcome measures…

AdultGerontologymedicine.medical_specialtyAdolescentReviewYoung Adult03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Age groupsNeoplasmsmedicinecancerHumansPatient reported outcome measures (PROMs)Patient Reported Outcome Measures030212 general & internal medicineYoung adultPsychiatryCancerQuality of Life ResearchHealth related quality of lifebusiness.industryPublic healthPublic Health Environmental and Occupational HealthCancermedicine.diseaseHealth-related quality of life (HRQoL)humanitiesadolescents and young adults (AYAs)030220 oncology & carcinogenesisQuality of LifeAdolescents and young adults (AYAs)health-related quality of life (HRQoL)businessPsychosocialpatient reported outcome measures (PROMs)Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
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The Influence of Music on Prefrontal Cortex during Episodic Encoding and Retrieval of Verbal Information: A Multichannel fNIRS Study.

2015

Music can be thought of as a complex stimulus able to enrich the encoding of an event thus boosting its subsequent retrieval. However, several findings suggest that music can also interfere with memory performance. A better understanding of the behavioral and neural processes involved can substantially improve knowledge and shed new light on the most efficient music-based interventions. Based on fNIRS studies on music, episodic encoding, and the dorsolateral prefrontal cortex (PFC), this work aims to extend previous findings by monitoring the entire lateral PFC during both encoding and retrieval of verbal material. Nineteen participants were asked to encode lists of words presented with eit…

AdultMaleBrain MappingSpectroscopy Near-InfraredArticle SubjectAdolescentFunctional NeuroimagingPrefrontal CortexNeurosciences. Biological psychiatry. Neuropsychiatrybehavioral disciplines and activitieshumanitiesYoung AdultAcoustic StimulationMental RecallHumansFemalehuman activitiesMusicRC321-571Research ArticleBehavioural neurology
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