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Decagram-Scale Synthesis of Multicolor Carbon Nanodots: Self-Tracking Nanoheaters with Inherent and Selective Anticancer Properties

2022

Carbon nanodots (CDs) are a new class of carbon-based nanoparticles endowed with photoluminescence, high specific surface area, and good photothermal conversion, which have spearheaded many breakthroughs in medicine, especially in drug delivery and cancer theranostics. However, the tight control of their structural, optical, and biological properties and the synthesis scale-up have been very difficult so far. Here, we report for the first time an efficient protocol for the one-step synthesis of decagram-scale quantities of N,S-doped CDs with a narrow size distribution, along with a single nanostructure multicolor emission, high near-infrared (NIR) photothermal conversion efficiency, and sel…

theranosticsMolecular StructureCell SurvivalInfrared RaysOptical ImagingAntineoplastic AgentsBiocompatible Materialstargeted cancer therapyCarbonCell Linemulticolor emissionMaterials TestingHumansNanoparticlesGeneral Materials Sciencecarbon nanodotshigh yield synthesisDrug Screening Assays AntitumorReactive Oxygen SpeciesCell Proliferation
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