Search results for "real-time"
showing 10 items of 881 documents
A hybrid algorithm for planning public charging stations
2014
International audience; Green mobility solutions are receiving currently an enormous attention. Indeed, during last years, electric vehicles, being part of the field of the smart-grid, entered the automobile market of the whole world. This technology requires an effective deployment of charging stations of electric refill since the main problem in this system remains over the duration of refill of the batteries. In this work, we propose an optimized algorithm to locate electric charging stations. The main task of the algorithm is to find the best site of charging stations locations so as to minimize loss on the way to the charging station, as well as minimize investment cost, we take into a…
AN OBJECT ORIENTED MODEL FOR SCHEDULING IN AGILE MANUFACTURING
2002
Agility represents a key factor in industry to handle the continuous market changes. Companies must re-organize their activities to be agile and competitive in such a dynamic environment. In particular, production planning and control tools are very important to optimize the manufacturing process responsiveness to sudden changes in customer demand. In this paper, an attempt has been made to develop an object-oriented software architecture that allows the optimal line organization to be determined once a set of parts to be produced has been ordered. An optimization module represented by a simulated annealing algorithm has been interfaced with an object oriented architecture to build up a fr…
Improved Performance in Quadrotor Trajectory Tracking Using MIMO PIλ-D Control
2022
This paper aims to develop a fractional control approach for quadrotor trajectory tracking. A fractional-order integrator (PIλ) with a feedback derivative scheme is designed to control each state of the MIMO system. The designed feedback controller stabilizes the initially unstable decoupled states and widens the stability, while PIλ provides precise trajectory tracking capabilities. After a successful simulation study, the new PIλ-D controller is implemented in the hardware environment. The various performance and load disturbance analyses reveal the effectiveness of the proposed scheme compared with the classical PD/PID controllers. The real-time study also shows that this scheme is a sim…
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis
2011
Heat shock proteins (HSPs) are necessary for cancer cell survival. We identified a mutant of HSP110 (HSP110ΔE9) in colorectal cancer showing microsatellite instability (MSI CRC), generated from an aberrantly spliced mRNA and lacking the HSP110 substrate-binding domain. This mutant was expressed at variable levels in almost all MSI CRC cell lines and primary tumors tested. HSP110ΔE9 impaired both the normal cellular localization of HSP110 and its interaction with other HSPs, thus abrogating the chaperone activity and antiapoptotic function of HSP110 in a dominant-negative manner. HSP110ΔE9 overexpression caused the sensitization of cells to anticancer agents such as oxaliplatin and 5-fluorou…
Gliadin activates arginase pathway in RAW264.7 cells and in human monocytes
2014
AbstractCeliac disease (CD) is an autoimmune enteropathy triggered in susceptible individuals by the ingestion of gliadin-containing grains. Recent studies have demonstrated that macrophages play a key role in the pathogenesis of CD through the release of inflammatory mediators such as cytokines and nitric oxide (NO). Since arginine is the obliged substrate of iNOS (inducible nitric oxide synthase), the enzyme that produces large amount of NO, the aim of this work is to investigate arginine metabolic pathways in RAW264.7 murine macrophages after treatment with PT-gliadin (PTG) in the absence and in the presence of IFNγ. Our results demonstrate that, besides strengthening the IFNγ-dependent …
A 16QAM super-orthogonal space-frequency code for broadband mobile communication systems with two transmit antennas
2010
We combine our previously designed 32-state super-orthogonal space-time trellis code (SOSTTC) with orthogonal frequency division multiplexing (OFDM) to build a broadband mobile communication system having a spectral efficiency that amounts to 4 bits/s/Hz depending on the length of the cyclic prefix used to avoid interframe interference. The transmitter is equipped with two antennas, where the OFDM frames they transmit are not independent, as they carry the same information in an orthogonal form. The 2N OFDM tones are grouped in N pairs of tones. Each group of two tones transmits the entries of a 2×2 orthogonal matrix. In our case, the entries are symbols taken from the rectangular 16-point …
Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy.
2009
Background Asthma pathogenesis involves gene and environmental interactions. A disintegrin and metalloprotease 33 (ADAM33)/Adam33 is a susceptibility gene for asthma and bronchial hyperresponsiveness in human beings and mice. ADAM33 is almost exclusively expressed in mesenchymal cells, including mesenchymal progenitors in developing lungs. Objective Because maternal allergy is a risk factor for asthma, we hypothesized that an allergic environment affects ADAM33/Adam33 expression during human and mouse lung development. Methods Human embryonic/fetal lung (HEL) tissues were collected from first-trimester terminations of pregnancy. These were processed immediately or used for explant culture ±…
High-Resolution Fluorescence Spectra of Airborne Biogenic Secondary Organic Aerosols: Comparisons to Primary Biological Aerosol Particles and Implica…
2021
Aqueous extracts of biogenic secondary organic aerosols (BSOAs) have been found to exhibit fluorescence that may interfere with the laser/light-induced fluorescence (LIF) detection of primary biological aerosol particles (PBAPs). In this study, we quantified the interference of BSOAs to PBAPs by directly measuring airborne BSOA particles, rather than aqueous extracts. BSOAs were generated by the reaction of d-limonene (LIM) or α-pinene (PIN) and ozone (O3) with or without ammonia in a chamber under controlled conditions. With an excitation wavelength of 355 nm, BSOAs exhibited peak emissions at 464–475 nm, while fungal spores exhibited peak emissions at 460–483 nm; the fluorescence intensit…
Identification of miR-187 and miR-182 as biomarkers of early diagnosis and prognosis in patients with prostate cancer treated with radical prostatect…
2014
Purpose: miRNAs are noncoding RNAs that negatively regulate target mRNA gene expression. Aberrant miRNA expression is associated with prostate cancer pathogenesis. We identified miRNAs as potential biomarkers for prostate cancer diagnosis and prognosis. Materials and Methods: Total RNA was obtained from 10 normal prostate and 50 prostate cancer samples, and analyzed using the GeneChip (R) miRNA 2.0 Array. At a median followup of 92 months (range 2 to 189) an independent cohort of 273 paraffin embedded prostate cancer samples was used for validation by quantitative reverse transcriptase-polymerase chain reaction. Another 92 urine samples from patients undergoing prostate biopsy were evaluate…
UWSim-NET: An Open-Source Framework for Experimentation in Communications for Underwater Robotics
2019
The communication with the remotely operated vehicles (ROV) in underwater applications are usually based on umbilical cables. The increase in the number of ROVs in cooperative interventions motivates the interest in underwater wireless communications. They have a high impact in robotic applications because of their limited performance in underwater scenarios. In this work we present UWSim-NET, an extension of the simulator for underwater robotics UWSim, which is based on the Robot Operating System (ROS). UWSim-NET integrates a communications module based on Network Simulator 3 (NS3) that allows to model the physical and data link layers. Experiments demonstrating the capabilities of UWSim-N…