Search results for "recurso"
showing 10 items of 734 documents
Inorganic Polyphosphates: Biologically Active Biopolymers for Biomedical Applications
2013
Inorganic polyphosphate (polyP) is a widely occurring but only rarely investigated biopolymer which exists in both prokaryotic and eukaryotic organisms. Only in the last few years, this polymer has been identified to cause morphogenetic activity on cells involved in human bone formation. The calcium complex of polyP was found to display a dual effect on bone-forming osteoblasts and bone-resorbing osteoclasts. Exposure of these cells to polyP (Ca2+ complex) elicits the expression of cytokines that promote the mineralization process by osteoblasts and suppress the differentiation of osteoclast precursor cells to the functionally active mature osteoclasts dissolving bone minerals. The effect o…
Direcció de Recursos Humans
2011
L'assignatura que desenvolupa la Funció de Recursos Humans té caràcter d'obligatòria en la branca de socials i s’imparteix en el primer quadrimestre del tercer curs del Grau en Relacions Laborals i Recursos Humans. La funció de Recursos Humans és una assignatura que intenta aprofundir en el coneixement dels conceptes relacionats amb les polítiques de recursos humans i la seua relació amb l'estratègia de la empresa. Enllaça amb les assignatures d'Introducció al funcionament de l'empresa, que permet abordar en profunditat el subsistema d'administració, el qual és objecte d'estudi en l'assignatura La direcció de l'empresa; i en la segona part d'Estructura de l'Organització. En tot cas, dins l'…
El patrimonio del comercio valenciano del frío
2004
El comercio del frío natural adquirió una gran importancia en el País Valenciano entre los siglos XVII y XIX. El artículo plantea algunas claves para su interpretación histórica y cultural. Presenta la red de depósitos de nieve (neveras y ventisqueros) y las actuaciones que se han desarrollado para conservar y revalorizar este singular patrimonio. (A)
Developmental outcomes of preterm birth: Cognitive and behavioural problems in moderately preterm children at preschool age
2012
Moderately preterm birth seems to be an evolutional risk condition at cognitive, behavioural and socio-relational levels. The study is aimed to investigate the likely occurrence of precursors of Attention Deficit Hyperactivity Disorder (ADHD) in moderately preterm children at preschool age. The research involved an experimental group made up of 50 moderately preterm children (mean: 34.6 weeks’ gestational age, standard deviation [SD]: 2) without any medical and neurologic neonatal complications and low birth weight (mean:2100g., SD: 350g.) and a check group of 50 full term born children. Parents and teachers of children were administered specific questionnaires to detect ADHD. The outcomes …
Early precursors of low attention and hyperactivity in children born late and very preterm at preschool age
2013
Moderately preterm birth seems to be an evolutional risk condition at cognitive, behavioural and socio-relational levels. The study is aimed to investigate the likely occurrence of precursors of Attention Deficit Hyperactivity Disorder (ADHD) in moderately preterm children at preschool age. The research involved an experimental group made up of 50 moderately preterm children (mean: 34.6 weeks’ gestational age, standard deviation [SD]: 2) without any medical and neurologic neonatal complications and low birth weight (mean:2100g., SD: 350g.) and a check group of 50 full term born children. Parents and teachers of children were administered specific questionnaires to detect ADHD. The outcomes …
La neonatologia nel ciclo di vita del materno infantile. Un percorso futuro
2012
Demonstration of an endocrine signaling circuit for insulin in the sponge Geodia cydonium.
1989
Abstract The existence of an insulin-mediated cell-to-cell signaling in the sponge Geodia cydonium is demonstrated in this study by molecular biological and immunological techniques. The sequence of a sponge cDNA clone encoding preproinsulin was analyzed for the first time and determined to comprise a high homology to human preproinsulin (60-80% homology). The predicted polypeptide of preproinsulin from sponge contains two disulfide bridges which link the A- to the B-chain. The intra-A chain disulfide bridge is absent. Applying immunological and electron microscopical techniques it is shown that insulin is produced in specialized cells (spherulous cells). Experimental evidence is presented …
Neurodevelopmental outcomes of moderately preterm birth: precursors of attention deficit hyperactivity disorder at preschool age
2013
Moderately preterm birth seems to be an evolutional risk condition at cognitive, behavioural and socio-relational levels. The study is aimed to investigate the likely occurrence of precursors of Attention Deficit Hyperactivity Disorder (ADHD) in moderately preterm children at preschool age. The research involved an experimental group made up of 50 moderately preterm children (mean: 34.6 weeks' gestational age, standard deviation [SD]: 2) without any medical and neurologic neonatal complications and low birth weight (mean:2100g., SD: 350g.) and a check group of 50 full term born children. Parents and teachers of children were administered specific questionnaires to detect ADHD. The outcomes …
Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo.
2009
Abstract Both the cellular prion protein (PrPc) and the amyloid precursor protein (APP) are physiologically subjected to complex proteolytic processing events. While for APP the proteinases involved – alpha-, beta- and gamma-secretase – have been identified in vitro and in vivo, the cleavage of PrPc by now has been linked only to the shedding activity of the metalloproteinase ADAM10 and/or ADAM17 in cell culture. Here we show that neuronal overexpression of the alpha-secretase ADAM10 in mice reduces all PrPc species detected in the brain instead of leading to enhanced amounts of specific cleavage products of PrPc. Additionally, the incubation time of mice after scrapie infection is signific…
Sobre el procedimiento de elaboración de los reglamentos, sus vicios y su control judicial
2021
El presente trabajo analiza algunas de las cuestiones más problemáticas y relevantes, tanto desde un punto de vista teórico como práctico, que en la actualidad plantea la regulación del procedimiento de elaboración de las normas reglamentarias: (i) la de los fines que debería perseguir esta regulación; (ii) la inadecuación de este procedimiento para elaborar ciertas disposiciones administrativas atípicas; (iii) la inadecuación de las estructuras organizativas actualmente encargadas de llevar a cabo las actividades en las que consiste dicho procedimiento; (iv) la evaluación ex post de los reglamentos; y (v) las consecuencias jurídicas derivadas de sus vicios de procedimiento y su control jud…