Search results for "reduction"

Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs

2004

Ischemia-reperfusion injury, a clinical problem during cardiac surgery, involves worsened adenosine trisphosphate (ATP) generation and damage to the heart. We studied carbon monoxide ( CO) pretreatment, proven valuable in rodents but not previously tested in large animals, for its effects on pig hearts subjected to cardiopulmonary bypass with cardioplegic arrest. Hearts of CO-treated pigs showed significantly higher ATP and phosphocreatine levels, less interstitial edema, and apoptosis of cardiomyocytes and required fewer defibrillations after bypass. We conclude that treatment with CO improves the energy status, prevents edema formation and apoptosis, and facilitates recovery in a clinical…

2016

Climate change is a major challenge for sustainable development, impacting human health, wellbeing, security, and livelihoods. While the post-2015 development agenda sets out action on climate change as one of the Sustainable Development Goals, there is little provision on how this can be achieved in tandem with the desired economic progress and the required improvements in health and wellbeing. This paper examines synergies and tensions between the goals addressing climate change and economic progress. We identify reductionist approaches in economics, such as ‘externalities’, reliance on the metric of the Gross Domestic Product, positive discount rates, and short-term profit targets as som…

PPGIS applied to environmental communication and hazards for a community-based approach: a dualism in the Southern Italy "calanchi" landscape

2021

<abstract> <p>The need of protection of the territory is a priority for the society, which is an integral part of it (unfortunately, this coincidence is often forgotten): the new environmental issues require the development of innovative management strategies and of appropriate knowledge and models. The balanced use of resources, essential for the survival and well-being of society, can be optimised through the promotion of the territory. The identification and the sustainable development of local resources can only be achieved by directing development policies towards a path of integration between ecological needs, protection of the landscape and socio-economic and cultural nee…

Sustainable Development: E-teaching (now) for Lifelong E-Learning

2011

Abstract To attain knowledge, add things every day. To attain wisdom, remove things every day. LAO TZU , “Tao Te Ching” The paper aims at convincing psychologist to cooperate in permanent education, by giving them a general idea about the first objectives of the PhD thesis titled “Nondeterministic e-Teaching for Sustainable Development in Rapidly Changing Environments”: a) Validating the role of e-teaching for sustainable development in Eastern Europe in line with the Europe 2020 strategy. (Europe 2020 is a 10-year strategy proposed by the European Commission on 3 March 2010 for reviving the economy of the European Union. It aims at “smart, sustainable, inclusive growth” with greater coordi…

Total Syntheses of Four Stereoisomers of 4α-Hydroxy-1β,7β-peroxy- 10βH-guaia-5-ene

2005

[reaction: see text]. The first total syntheses of four stereoisomers of 4alpha-hydroxy-1beta,7beta-peroxy-10betaH-guaia-5-ene are reported starting from the readily available (+)-dihydrocarvone. These compounds have been synthesized from dienes (-)-isoguaiene and (-)-10-epi-isoguaiene by tandem ene hydroperoxylation-[4 + 2] cycloaddition with O(2) followed by selective reduction. The structure of the natural 4alpha-hydroxy-1beta,7beta-peroxy-10betaH-guaia-5-ene isolated from Liabum floribundum has been confirmed.

Enhancing salty taste through odour–taste–taste interactions: Influence of odour intensity and salty tastants’ nature

2013

WOS:000315557500017 ; www.elsevier.com/locate/foodqual; International audience; Decreasing the sodium content in food products without changing consumer acceptability has become an important challenge for the food industry, and several strategies are currently under investigation to reach this goal. This study investigated the effectiveness of saltiness enhancement by an odour to maintain the perception of saltiness in reduced salt content solutions. In the first experiment, we tested the hypothesis that odour intensity drives the level of saltiness enhancement. The results showed that odour can increase the salty intensity by 25%, while no clear influence of odour intensity either in taste…

Improving the Performance of Steel Machining Processes through Cutting by Vibration Control

2021

Machining processes through cutting are accompanied by dynamic phenomena that influence the quality of the processed surfaces. Thus, this research aimed to design, make, and use a tool with optimal functional geometry, which allowed a reduction of the dynamic phenomena that occur in the cutting process. In order to carry out the research, the process of cutting by front turning with transversal advance was taken into account. Additionally, semi-finished products with a diameter of Ø = 150 mm made of C45 steel were chosen for processing (1.0503). The manufacturing processes were performed with the help of two tools: a cutting tool, the classic construction version, and another that was the i…

In Situ Regeneration of Copper-Coated Gas Diffusion Electrodes for Electroreduction of CO2 to Ethylene

2021

This research was funded by the European Union’s Horizon 2020 research and innovation program under grant agreement No 768789 as well as by the Polish National Centre of Science under grant no 2017/26/D/ST8/00508. The Institute of Solid State Physics, University of Latvia, as a center of excellence, has received funding from the European Union’s Horizon 2020 Framework Programme H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under grant agreement no. 739508, project CAMART2.

Glutathione regulates telomerase activity in 3T3 fibroblasts.

2004

Changes in telomerase activity have been associated either with cancer, when activity is increased, or with cell cycle arrest when it is decreased. We report that glutathione, a physiological antioxidant present at high intracellular concentrations, regulates telomerase activity in cells in culture. Telomerase activity increases in 3T3 fibroblasts before exponential cell growth. The peak of telomerase activity takes place 24 h after plating and coincides with the maximum levels of glutathione in the cells. When cells are treated with buthionine sulfoximine, which decreases glutathione levels in cells, telomerase activity decreases by 60%, and cell growth is delayed. Glutathione depletion in…

Interior Permanent Magnet Synchronous Machine Drive Powered by Fuel Cell for Automotive Applications

2020

Electric vehicles represent an optimal solution for the reduction of pollution in urban areas. In particular, the Fuel Cell (FC) technology is a promising solution especially for its charging times and zero CO2 direct emissions. The paper addresses the design and performance study of an Interior Permanent Magnet Synchronous Machine (IPMSM) drive powered by fuel cell for automotive applications. The IPMSM drive is powered by the use of 5,5 kW FC unit and it is composed of two DC-DC power converters and one inverter. In detail, a test bench has been carried out for the evaluation of the performances of each IPMSM drive conversion stage. Moreover, in order to simulate automotive working condit…