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showing 10 items of 634 documents

Spectrum of congenital anomalies in pregnancies with pregestational diabetes

2012

BACKGROUND Maternal pregestational diabetes is a well-known risk factor for congenital anomalies. This study analyses the spectrum of congenital anomalies associated with maternal diabetes using data from a large European database for the population-based surveillance of congenital anomalies. METHODS: Data from 18 population-based EUROCAT registries of congenital anomalies in 1990-2005. All malformed cases occurring to mothers with pregestational diabetes (diabetes cases) were compared to all malformed cases in the same registry areas to mothers without diabetes (non-diabetes cases). RESULTS: There were 669 diabetes cases and 92,976 non diabetes cases. Odds ratios in diabetes pregnancies re…

MaleEmbryologyPediatricsPregestational DiabetesPregnancy in DiabeticsMELLITUSPregnancyRisk FactorsNeural Tube DefectsRegistriesLivebirthsRISKeducation.field_of_studyOUTCOMESlivebirthsWOMENEarGeneral MedicineASSOCIATIONCongenital AnomaliesEuropeAnotiaPopulation SurveillanceFemaleNEURAL-TUBE DEFECTSLive BirthHernia UmbilicalAdultHeart Defects Congenitalmedicine.medical_specialtyPopulationPopulation Basedpopulation basedCongenital AbnormalitiesYoung AdultDiabetes mellitusAnencephalyBIRTH-DEFECTSmedicineDiabetes MellitusHumansMALFORMATIONSRisk factoreducationTYPE-1Congenital MicrotiaOmphaloceleSpina bifidabusiness.industrycongenital anomaliesInfant NewbornOdds ratioNATIONWIDEmedicine.diseaseEstados de Saúde e de Doençapregestational diabetesPregnancy ComplicationsPediatrics Perinatology and Child HealthbusinessDevelopmental BiologyBirth Defects Research. Part A: Clinical and Molecular Teratology
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Temporal trends in prehospital management of ST-segment elevation myocardial infarction from 2002 to 2010 in Cote d’Or: Data from the RICO registry (…

2012

Summary Background Myocardial infarction with ST-segment elevation (STEMI) is a medical emergency requiring specific management, with the main aim of achieving reperfusion as quickly as possible. Guidelines from medical societies have defined optimal management, with proven efficacy on morbi-mortality. Aims Our study aimed to evaluate trends in practices between 2002 and 2010 in the emergency management of STEMI in a single French department, namely Cote d’Or. Methods All patients admitted with a first STEMI to one of the six participating coronary care units (private or public) in Cote d’Or since January 2001 were included in a prospective registry (obseRvatoire des Infarctus de Cote d’Or …

MaleEmergency Medical ServicesFirst medical contactTime delaysTime FactorsMyocardial InfarctionTemporal trendsÉvolutionSTEMIHumansST segmentMedicineProspective StudiesRegistriesMyocardial infarctionManagement practicesEmergency managementbusiness.industryGeneral MedicineMiddle AgedDélaismedicine.diseaseOptimal managementTime delaysReperfusionFemaleFranceMedical emergencyCardiology and Cardiovascular MedicinebusinessArchives of Cardiovascular Diseases
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The Full Revasc (Ffr-gUidance for compLete non-cuLprit REVASCularization) Registry-based randomized clinical trial

2021

Publisher Copyright: © 2021 Background: Complete revascularization in ST elevation myocardial infarction (STEMI) patients with multivessel disease has resulted in reduction in composite clinical endpoints in medium sized trials. Only one trial showed an effect on hard clinical endpoints, but the revascularization procedure was guided by angiographic evaluation of stenosis severity. Consequently, it is not clear how Fractional Flow Reserve (FFR)-guided percutaneous coronary intervention (PCI) affects hard clinical endpoints in STEMI. Methods and Results: The Ffr-gUidance for compLete non-cuLprit REVASCularization (FULL REVASC) – is a pragmatic, multicenter, international, registry-based rand…

MaleEmergency Medical Servicesmedicine.medical_treatmentFractional flow reserve030204 cardiovascular system & hematologyCoronary AngiographyGUIDELINESSeverity of Illness IndexANGIOGRAPHYDISEASElaw.invention0302 clinical medicineRandomized controlled triallawFRACTIONAL FLOW RESERVEClinical endpointMedicineCardiac and Cardiovascular Systems030212 general & internal medicineRegistriesKardiologiMiddle Aged3. Good healthFractional Flow Reserve MyocardialOutcome and Process Assessment Health CareSurgery Computer-AssistedCardiologyFemaleCardiology and Cardiovascular Medicinemedicine.medical_specialtyRevascularizationCulpritLESION03 medical and health sciencesPercutaneous Coronary InterventionInternal medicineHumanscardiovascular diseasesMortalityANGIOPLASTYAgedbusiness.industryCoronary StenosisELEVATION MYOCARDIAL-INFARCTIONPercutaneous coronary interventionmedicine.disease3126 Surgery anesthesiology intensive care radiologyStenosis3121 General medicine internal medicine and other clinical medicineConventional PCIST Elevation Myocardial Infarctionbusiness
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Childhood central nervous system tumours – incidence and survival in Europe (1978–1997): Report from Automated Childhood Cancer Information System pr…

2006

Abstract This paper describes the incidence and survival of childhood central nervous system (CNS) tumours in Europe for the period 1978–1997. A total of 19,531 cases, aged 0–14 years, from the ACCIS database were analysed by five regions: the British Isles, East, North, South, and West. Overall age-standardised incidence rate (ASR) of CNS tumours in Europe (1988–1997) was 29.9 per million, with the highest rates in the North. Astrocytoma (ASR = 11.8), primitive neuroectodermal tumours (PNET) (ASR = 6.5) and ependymoma (ASR = 3.4) were the most frequent types. Incidence increased significantly during 1978–1997, on average by 1.7% per year. Diagnostic methods may partially explain incidence …

MaleEpendymomaCancer Researchmedicine.medical_specialtyAdolescentDatabases FactualChildhood cancerCentral nervous systemCentral Nervous System NeoplasmsEpidemiologymedicineHumansRegistriesChildcentral nervous system tumoursbusiness.industryIncidenceIncidence (epidemiology)Infant NewbornInfantChildhood cancers - survival - time trends; central nervous system tumoursAstrocytomaCancermedicine.diseaseSurvival AnalysisSurgeryEuropemedicine.anatomical_structureOncologyEl NiñoChild PreschoolFemalebusinessChildhood cancers - survival - time trendsDemographyEuropean Journal of Cancer
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Trends of incidence and survival in squamous-cell carcinoma of the anal canal in France: a population-based study.

2016

IF 2.415; International audience; Data on anal cancer epidemiology are rare. The aim of this study was to report on trends of incidence and survival for anal cancer in France before the implementation of the human papilloma virus vaccine. This analysis was carried out on 1150 squamous-cell carcinomas of the anal canal diagnosed from 1989 to 2004 in a population of 5.7 million people covered by eight population-based cancer registries. Time trends in incidence were modeled using an age-period-cohort model. Net survival rates were obtained using the recently validated unbiased Pohar-Perme estimator. The incidence of squamous-cell carcinoma of the anal canal increased from 0.2 to 0.5/100 000 p…

MaleEpidemiologyMESH : Aged[ SDV.CAN ] Life Sciences [q-bio]/CancerMESH: Anus NeoplasmsMESH: Research Papers: Gastrointestinal Cancer0302 clinical medicineMESH : ChildMESH: ChildMedicineMESH: IncidenceMESH : Carcinoma Squamous CellChildeducation.field_of_studyMESH: Middle AgedObstetricsMESH : InfantMESH: Carcinoma Squamous CellMESH: Follow-Up StudiesAnal canalAnus NeoplasmsPrognosisResearch PapersMESH: InfantMESH : Incidence3. Good healthSurvival RateOncologyMESH: Young AdultChild Preschool030220 oncology & carcinogenesisCarcinoma Squamous Cell030211 gastroenterology & hepatologymedicine.medical_specialtyMESH : Research Papers: Gastrointestinal CancerMitomycinMESH : Young AdultUnited-StatesMESH: Prognosis03 medical and health sciencesMESH : AdolescentHumansAnal cancerMESH : Middle AgedMESH : Anus NeoplasmseducationAgedGynecologyMESH: AdolescentMESH: HumansMESH : HumansMESH: Child PreschoolPublic Health Environmental and Occupational HealthInfantMESH : Follow-Up StudiesMESH: AdultEpidermoid Carcinomamedicine.diseaseCervical-cancerincidenceRandomized-trialMESH: FemaleCancer ResearchMESH: RegistriesMESH : Child PreschoolRisk FactorsMESH: Risk FactorsMESH : FemaleRegistriesCervical cancerMESH: AgedMESH : PrognosisIncidence (epidemiology)SmokingMESH: Infant NewbornMESH : AdultMiddle AgedMESH : Survival RateMESH : Risk Factorsmedicine.anatomical_structureFemaleFranceAdultHuman-PapillomavirusRiskAdolescentMESH: Survival Rateanal cancerMESH : MalePopulationHuman Papilloma Virus Vaccine[SDV.CAN]Life Sciences [q-bio]/CancerCancer IncidenceMESH : Infant NewbornsurvivalYoung Adultcancer registryMESH : FranceSurvival rateRadiotherapybusiness.industryInfant NewbornCancerMESH: MaleMESH: FrancebusinessMESH : RegistriesFollow-Up Studies
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The family-oriented Open Dialogue approach in the treatment of first-episode psychosis : nineteen–year outcomes

2018

Open Dialogue (OD) is a family-oriented early intervention approach which has demonstrated good outcomes in the treatment of first-episode psychosis (FEP). Nevertheless, more evidence is needed. In this register-based cohort study the long-term outcomes of OD were evaluated through a comparison with a control group over a period of approximately 19 years. We examined the mortality, the need for psychiatric treatment, and the granting of disability allowances. Data were obtained from Finnish national registers regarding all OD patients whose treatment for FEP commenced within the time of the original interventions (total N = 108). The control group consisted of all Finnish FEP patients who h…

MaleFamily therapyPsychological interventionlong-term follow-upwork capabilitylaw.inventionCohort Studies0302 clinical medicineRandomized controlled triallawOutcome Assessment Health CareMedicinetyökykyRegistriesFinlanddisability pensionperheterapiaMiddle AgedPsychiatry and Mental healthSchizophreniaFemalefamily therapyseurantatutkimusCohort studyAdultkuolleisuusmedicine.medical_specialtyAdolescentYoung Adult03 medical and health sciencesEarly Medical InterventionFirst episode psychosisHumansPsychiatryBiological PsychiatryAgedskitsofreniabusiness.industryDisability pensionmedicine.diseasemortalityta3124030227 psychiatryschizophreniaantipsychoticshospital admissionPsychotic DisorderstyökyvyttömyyseläkkeetObservational studybusiness030217 neurology & neurosurgeryPsychiatry Research
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Essay: Does training adversely affect long-term health?

2005

A number of philosophers and physicians living in ancient Greece thought that sport could harm both mind and body. Hippocrates, for example, acknowledged the health benefits of physical activity, but also believed that intense athletic competition had a harmful effect on the heart and other organs, and lowered resistance to disease. That athletes do not have a shorter life expectancy than the general population, however, was not appreciated until the 19th century. In 1873, J E Morgan published the results of his study of 294 British oarsmen who participated in the Oxford versus Cambridge boat races between 1829 and 1869. His findings indicated that these sportsmen lived about 2 years longer…

MaleGerontologymedicine.medical_specialtyBasketballHealth StatusPhysical ExertionPopulationResistance (psychoanalysis)Affect (psychology)Oxygen ConsumptionRisk FactorsmedicineHumansProspective StudiesRegistrieseducationTrack and field athleticsFinlandeducation.field_of_studybiologybusiness.industryAthletesVO2 maxGeneral Medicinebiology.organism_classificationDeath Sudden CardiacLife expectancyPhysical therapybusinesshuman activitiesSportsThe Lancet
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The influence of geographical access to health care and material deprivation on colorectal cancer survival: Evidence from France and England

2014

International audience; This article investigates the influence of distance to health care and material deprivation on cancer survival for patients diagnosed with a colorectal cancer between 1997 and 2004 in France and England. This population-based study included all cases of colorectal cancer diagnosed between 1997 and 2004 in 3 cancer registries in France and 1 cancer registry in England (N=40,613). After adjustment for material deprivation, travel times in England were no longer significantly associated with survival. In France patients living between 20 and 90min from the nearest cancer unit tended to have a poorer survival, although this was not statistically significant. In England, …

MaleHealth (social science)Colorectal cancerGeography Planning and DevelopmentPopulationcolorectal cancer[SDV.CAN]Life Sciences [q-bio]/CancersurvivalHealth Services AccessibilityHealth services[SDV.CAN] Life Sciences [q-bio]/CancerHealth caremedicineHumansRegistrieseducationmaterial deprivationAgedTraveleducation.field_of_studyGeographybusiness.industrytravel timesPublic Health Environmental and Occupational HealthCancerCancer survivalMiddle Agedmedicine.diseaseHealth care accessibility3. Good healthCancer registryEnglandFemaleFranceColorectal NeoplasmsbusinessDemographyHealth & Place
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Accelerometer-determined physical activity and self-reported health in a population of older adults (65-85 years): a cross-sectional study.

2013

Background The link between physical activity (PA) and prevention of disease, maintenance of independence, and improved quality of life in older adults is supported by strong evidence. However, there is a lack of data on population levels in this regard, where PA level has been measured objectively. The main aims were therefore to assess the level of accelerometer-determined PA and to examine its associations with self-reported health in a population of Norwegian older adults (65–85 years). Methods This was a part of a national multicenter study. Participants for the initial study were randomly selected from the national population registry, and the current study included those of the initi…

MaleHealth StatusPersonal SatisfactionPhysical activity levelSurveys and QuestionnairesAccelerometryActivities of Daily LivingHumansRegistriesExerciseLife StyleAgedAged 80 and overNorwayAge FactorsMiddle AgedAccelerometerCross-Sectional StudiesQuality of LifeRegression AnalysisFemaleGuideline AdherenceSelf ReportSedentary BehaviorSelf-reported healthOlder peopleResearch ArticleBMC public health
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Prognostic Value of Initial Left Ventricular Remodeling in Patients With Reperfused STEMI

2019

Abstract Objectives This study sought to establish the best definition of left ventricular adverse remodeling (LVAR) to predict outcomes and determine whether its assessment adds prognostic information to that obtained by early cardiac magnetic resonance (CMR). Background LVAR, usually defined as an increase in left ventricular end-diastolic volume (LVEDV) is the main cause of heart failure after an ST-segment elevated myocardial infarction; however, the role of assessment of LVAR in predicting cardiovascular events remains controversial. Methods Patients with ST-segment elevated myocardial infarction who received percutaneous coronary intervention within 6 h of symptom onset were included …

MaleLeft ventricular ejection fractionTime FactorsDatabases FactualCardiac magnetic resonancemedicine.medical_treatment030204 cardiovascular system & hematologyLeft ventricular end-diastolic volumeInfarct sizeVentricular Function Left030218 nuclear medicine & medical imaging0302 clinical medicineRisk FactorsCause of DeathClinical endpointMyocardial infarctionRegistriesRandomized Controlled Trials as TopicEjection fractionVentricular RemodelingHazard ratioMiddle AgedMicrovascular obstructionPrognosisMagnetic Resonance ImagingHospitalizationTreatment OutcomeCardiologyEnd-diastolic volumeFemaleCardiology and Cardiovascular Medicinemedicine.medical_specialtyLeft ventricular end-systolic volume03 medical and health sciencesPercutaneous Coronary InterventionPredictive Value of TestsInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingVentricular remodelingAgedHeart Failurebusiness.industryLeft ventricular remodelingPercutaneous coronary interventionArrhythmias CardiacStroke VolumeRecovery of Functionmedicine.diseaseST-segment elevation myocardial infarctionHeart failureST Elevation Myocardial Infarctionbusiness
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