Search results for "registries"

showing 10 items of 615 documents

Anticoagulant drugs in noncompaction: A mandatory therapy?

2008

BACKGROUND: Noncompaction of left ventricular myocardium is a rare congenital cardiomyopathy resulting from an incomplete myocardial morphogenesis that leads to the persistence of the embryonic myocardium. This condition is characterized by a thin compacted epicardial and an extremely thickened endocardial layer with prominent trabeculations and deep intertrabecular recesses. It is not clear, in noncompaction of myocardium, whether intertrabecular recesses could be responsible for thrombi formation and thromboembolic complications. METHODS: The prevalence of stroke and echocardiographic finding of thrombus was evaluated in a continuous series of 229 patients (men and women) affected by nonc…

MaleRegistrieTime FactorsEmbolismAdministration OralHeart VentricleRisk FactorsRegistriesStrokeIschemic strokeAnticoagulantCongenital cardiomyopathyGeneral MedicineMiddle AgedStrokeAnticoagulant drugsCardiologycardiovascular systemFemaleAnticoagulant drugs noncompactionCardiomyopathiesCardiology and Cardiovascular MedicineHumanAdultHeart Defects Congenitalmedicine.medical_specialtyStroke etiologyTime Factormedicine.drug_classIsolated left ventricular noncompactionHeart Ventriclesanticoagulant; embolism; ischemic stroke; Isolated left ventricular noncompactionInternal medicineThromboembolismmedicineHumanscardiovascular diseasesThrombusNoncompactionCardiomyopathiebusiness.industryRisk FactorAnticoagulantAnticoagulantsInfantmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareEmbolismIschemic strokeThrombuLeft ventricular myocardiumbusiness
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Identification of optimal device combinations for the chimney endovascular aneurysm repair technique within the PERICLES registry

2018

Abstract Objective The ideal stent combination for chimney endovascular aneurysm repair remains undetermined. Therefore, we sought to identify optimal aortic and chimney stent combinations that are associated with the best outcomes by analyzing the worldwide collected experience in the PERformance of chImney technique for the treatment of Complex aortic pathoLogiES (PERICLES) registry. Methods The PERICLES registry was reviewed for patients with pararenal aortic disease electively treated from 2008 to 2014. Eleven different aortic devices were identified with three distinct subgroups: group A (n = 224), nitinol/polyester; group B (n = 105), stainless steel/polyester; and group C (n = 69), n…

MaleRegistrieTime FactorsEndoleakmedicine.medical_treatmentComorbidity030204 cardiovascular system & hematology030230 surgeryEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortic aneurysm0302 clinical medicineRisk FactorsRetrospective StudieOcclusionOdds RatioStentRegistriesMultivariate AnalysiPolytetrafluoroethyleneAged 80 and overEndovascular ProceduresHazard ratioGraft Occlusion VascularEuropeBlood Vessel ProsthesiTreatment OutcomeCardiothoracic surgeryStentsFemaleCardiology and Cardiovascular MedicineSTENT GRAFT; CHIMENY GRAFT; CHIMNEY TECHINQUEHumanUnited Statemedicine.medical_specialtyHospitals Low-VolumeTime FactorPolyestersPolyesterProsthesis DesignDisease-Free Survival03 medical and health sciencesBlood Vessel Prosthesis ImplantationBlood vessel prosthesisAlloysmedicineHumansProportional Hazards ModelsRetrospective StudiesAgedEndovascular ProcedureAortic Aneurysm Thoracicbusiness.industryRisk FactorStentOdds ratiomedicine.diseaseStainless SteelUnited StatesBlood Vessel ProsthesisSurgeryMultivariate AnalysisAlloyProportional Hazards ModelSurgerybusinessHospitals High-VolumeAortic Aneurysm Abdominal
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Replacement therapy for bleeding episodes in factor VII deficiency: A prospective evaluation

2013

Patients with inherited factor VII (FVII) deficiency display different clinical phenotypes requiring ad hoc management. This study evaluated treatments for spontaneous and traumatic bleeding using data from the Seven Treatment Evaluation Registry (STER). One-hundred one bleeds were analysed in 75 patients (41 females; FVII coagulant activity <1-20%). Bleeds were grouped as haemarthroses (n=30), muscle/subcutaneous haematomas (n=16), epistaxis (n=12), gum bleeding (n=13), menorrhagia (n=16), central nervous system (CNS; n=9), gastrointestinal (GI; n=2) and other (n=3). Of 93 evaluable episodes, 76 were treated with recombinant, activated FVII (rFVIIa), eight with fresh frozen plasma (FFP), s…

MaleRegistrieTime FactorsFactor VII Deficiency030204 cardiovascular system & hematologyReplacement therapyProspective evaluationchemistry.chemical_compound0302 clinical medicineMedicineProspective StudiesRegistriesYoung adultProspective cohort studyFactor VII deficiencyChildHematologyFactor VIIHematologyMiddle AgedRecombinant ProteinBlood Coagulation FactorsRecombinant ProteinsTreatment OutcomeCoagulantChild PreschoolFemaleBlood Coagulation FactorHumanAdultmedicine.medical_specialtyAdolescentTime FactorHemorrhageBlood Component TransfusionFactor VIIaBleeds; Factor VII deficiency; Replacement therapy; Adolescent; Adult; Aged; Blood Coagulation Factors; Child; Child Preschool; Coagulants; Drug Administration Schedule; Factor VII Deficiency; Factor VIIa; Female; Hemorrhage; Humans; Infant; Infant Newborn; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Registries; Time Factors; Treatment Outcome; Young Adult; Blood Component Transfusion; HematologyDrug Administration Schedule03 medical and health sciencesYoung AdultInternal medicineHumansAgedBleeding episodesbusiness.industryCoagulantsInfant NewbornInfantSurgeryProspective StudieTreatment evaluationchemistryBleedbusiness030215 immunology
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Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics

2018

International audience; Importance - The natural history and the management of patients with asymptomatic aortic stenosis (AS) have not been fully examined in the current era. Objective - To determine the clinical outcomes of patients with asymptomatic AS using data from the Heart Valve Clinic International Database. Design, setting, and participants - This registry was assembled by merging data from prospectively gathered institutional databases from 10 heart valve clinics in Europe, Canada, and the United States. Asymptomatic patients with an aortic valve area of 1.5 cm2 or less and preserved left ventricular ejection fraction (LVEF) greater than 50% at entry were considered for the prese…

MaleRegistrieUnited StateCanadamedicine.medical_specialty030204 cardiovascular system & hematologyAsymptomaticSudden deathDisease-Free Survival03 medical and health sciences0302 clinical medicineAortic valve replacementRetrospective StudieInternal medicinemedicineHumansProspective StudiesRegistries030212 general & internal medicineHeart valveWatchful WaitingProspective cohort studyRetrospective StudiesAgedAged 80 and overAsymptomatic DiseaseEjection fractionbusiness.industryDisease ManagementAortic Valve StenosisMiddle Agedmedicine.diseaseAortic Valve StenosiUnited States3. Good healthEuropeProspective StudieStenosisDeath Sudden Cardiacmedicine.anatomical_structureAortic valve stenosisAsymptomatic DiseasesCardiology[SDV.IB]Life Sciences [q-bio]/BioengineeringFemalemedicine.symptombusinessCardiology and Cardiovascular MedicineHuman
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Childhood and Adolescence Cancers in the Palermo Province (Southern Italy): Ten Years (2003-2012) of Epidemiological Surveillance

2018

Italy has one of the highest paediatric cancer incidence rates in Europe. We compared cancer incidence and survival rates in children (0&ndash

MaleRegistriecancer incidencejointpoint regressionHealth Toxicology and Mutagenesislcsh:MedicineSettore MED/42 - Igiene Generale E Applicata0302 clinical medicineNeoplasmsMedicine030212 general & internal medicineRegistriesYoung adultcancer survivalChildeducation.field_of_studyIncidence (epidemiology)Incidenceepidemiological surveillancepopulation-based cancer registrieSurvival RateItaly030220 oncology & carcinogenesisChild PreschoolFemaleHumanpopulation-based cancer registriesAdolescentPopulationDisease clusterArticle03 medical and health sciencesYoung AdultHumanseducationSurvival rateSurvival analysistime trendsbusiness.industrylcsh:RPublic Health Environmental and Occupational HealthCancerInfantmedicine.diseaseCancer registrytime trendNeoplasmbusinesscancer in childhood and adolescenceDemography
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The first report of the Italian Migraine Registry (I-GRAINE).

2022

Italian Migraine Registry (I-GRAINE) is a multicenter (n = 38), prospective, observational, non-interventional study aimed at providing big data on migraine to ensure proper clinical disease management, according to scientific, and sustainability criteria. We enrolled consecutive patients affected by episodic or chronic migraine according to the systematic random method. Information on sociodemographic characteristics, lifestyle, migraine features, patient's journey, and healthcare resource use were gathered using face-to-face interviews.On the date of 31 December 2021, we enrolled 231 patients at 12 headache centers. Most of them were women (84.4%), with high migraine frequency (9.6 +/- 6.…

MaleRegistryHealthcare resource useMigraine DisordersHeadacheHealthcare resource use; Migraine; Patient’s journey; Registry; TreatmentDermatologyGeneral MedicineTryptaminesTreatmentPsychiatry and Mental healthHumansSettore MED/26 - NeurologiaFemaleNeurology (clinical)Prospective StudiesRegistriesPatient’s journeyMigraineNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
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The Use of Computer Navigation in Total Hip Arthroplasty Is Associated with a Reduced Rate of Revision for Dislocation

2021

BACKGROUND: The use of computer navigation has been shown to produce more accurate cup positioning when compared with non-navigated total hip arthroplasty (THA), but so far there is only limited evidence to show its effect on clinical outcomes. The present study analyzed data from the Australian Orthopaedic Association National Joint Replacement Registry to assess the impact of computer navigation on the rates of all-cause revision and revision for dislocation following THA. METHODS: Data for all non-navigated and navigated primary THAs performed for osteoarthritis in Australia from January 1, 2009, to December 31, 2019, were examined to assess the rate of revision. We analyzed the effects …

MaleReoperationmedicine.medical_specialtyArthroplasty Replacement HipOsteoarthritisProsthesis DesignOsteoarthritis Hip03 medical and health sciencesPostoperative Complications0302 clinical medicineHip DislocationHumansMedicineOrthopedics and Sports MedicineComputer navigationRegistriesAged030222 orthopedicsbusiness.industryHazard ratioGeneral MedicineMiddle Agedmedicine.diseaseConfidence intervalProsthesis FailureSurgerySurgery Computer-AssistedJoint replacement registry030220 oncology & carcinogenesisOrthopedic surgeryCohortFemaleSurgerybusinessTotal hip arthroplastyJournal of Bone and Joint Surgery
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Procedural, Functional and Prognostic Outcomes Following Recanalization of Coronary Chronic Total Occlusions. Results of the Iberian Registry.

2019

Introduction and objectives: There is current controversy regarding the benefits of percutaneous recanalization (PCI) of chronic total coronary occlusions (CTO). Our aim was to determine acute and follow-up outcomes in our setting. Methods: Two-year prospective registry of consecutive patients undergoing PCI of CTO in 24 centers. Results: A total of 1000 PCIs of CTO were performed in 952 patients. Most were symptomatic (81.5%), with chronic ischemic heart disease (59.2%). Previous recanalization attempts had been made in 15%. The mean SYNTAX score was 19.5 +/- 10.6 and J-score was > 2 in 17.3%. A retrograde procedure was performed in 92 patients (9.2%). The success rate was 74.9% and was hi…

MaleReoperationmedicine.medical_specialtyPercutaneousmedicine.medical_treatmentPerforation (oil well)Myocardial Ischemia030204 cardiovascular system & hematology03 medical and health sciencesPercutaneous Coronary InterventionPostoperative Complications0302 clinical medicineInternal medicineMyocardial RevascularizationmedicineHumansProspective StudiesRegistriesMyocardial infarctionProspective cohort studyUltrasonography InterventionalAgedPortugalbusiness.industryMortality ratePercutaneous coronary interventionGeneral Medicinemedicine.diseaseTreatment OutcomeCoronary OcclusionSurgery Computer-AssistedSpainCoronary occlusionChronic DiseaseConventional PCICardiologyFemaleCTO Cardiopatía isquémica crónica Chronic ischemic cardiomyopathy Chronic total occlusions IVUS OCT Oclusiones crónicasbusiness
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Epidemiological studies of cancer in aircrew.

2009

Exposure to cosmic ionising radiation, in addition to other specific occupational risks, is of concern to aircrew members. Epidemiological studies provide an objective way to assess the health of this occupational group. We systematically reviewed the epidemiological literature on health of aircrew members since 1990, focusing on cancer as the endpoint of interest. Sixty-five relevant publications were identified and reviewed. Whereas overall cancer incidence and mortality was generally lower than in the comparison population, consistently elevated risks were reported for breast cancer incidence in female aircrew members and for melanoma in both male and female aircrew members. Brain cancer…

MaleRiskmedicine.medical_specialtyOccupational groupNeoplasms Radiation-InducedAircraftUltraviolet RaysPopulationBreast cancerEnvironmental healthNeoplasmsOccupational ExposureEpidemiologymedicineHumansRadiology Nuclear Medicine and imagingRegistrieseducationeducation.field_of_studyRadiationRadiological and Ultrasound Technologybusiness.industryBrain NeoplasmsIncidence (epidemiology)IncidencePublic Health Environmental and Occupational HealthCancerGeneral Medicinemedicine.diseaseOccupational DiseasesCancer incidenceAircrewFemalebusinessCosmic RadiationRadiation protection dosimetry
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Ejection Fraction by Echocardiography for a Selective Use of Magnetic Resonance After Infarction

2020

[EN] Background Cardiac magnetic resonance (CMR) permits robust risk stratification of discharged ST-segment-elevation myocardial infarction patients, but its indiscriminate use in all cases is not feasible. We evaluated the utility of left ventricular ejection fraction (LVEF) by echocardiography for a selective use of CMR after ST-segment-elevation myocardial infarction. Methods Echocardiography and CMR were performed in 1119 patients discharged for ST-segment-elevation myocardial infarction included in a multicenter registry. The prognostic power of CMR beyond echocardiography-LVEF was assessed using adjusted C statistic, net reclassification improvement index, and integrated discriminati…

MaleRiskmedicine.medical_specialtyVentricular Ejection FractionTime FactorsInfarctionMagnetic Resonance Imaging CineHeart failurePatient ReadmissionVentricular Function LeftTECNOLOGIA ELECTRONICAVentricular Dysfunction LeftPercutaneous Coronary InterventionPredictive Value of TestsInternal medicinemedicineHumansVentricular ejection fractionRadiology Nuclear Medicine and imagingcardiovascular diseasesMyocardial infarctionProspective StudiesRegistriesAgedEjection fractionmedicine.diagnostic_testbusiness.industryReproducibility of ResultsMagnetic resonance imagingStroke VolumeMiddle Agedmedicine.diseasePrognosisNet reclassification improvementMyocardial infarctionTreatment OutcomeEchocardiographyMagnetic resonanceHeart failurecardiovascular systemCardiologyST Elevation Myocardial InfarctionFemaleCardiology and Cardiovascular MedicinebusinessMacecirculatory and respiratory physiology
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